Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 945004-44-4 | MDL No. : | MFCD18791599 |
Formula : | C8H6F2O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | - |
M.W : | 156.13 | Pubchem ID : | - |
Synonyms : |
|
Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | |
Hazard Statements: | H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
74% | A. 3-(Difluoromethyl)benzaldehyde.; 3-(Difluoromethyl)-l-bromobenzene(1.0 g, 4.83 mmol) was dissolved in anhydrous tetrahydrofuran (20 mL) and cooled to -78 0C. n-Butyl lithium (1.6M, 3.2 mL, 5.07 mmol) was added and the reaction stirred for 30 min. Dimethylformamide (1 mL) was added and the solution was allowed to warm to room temperature. The reaction was quenched with saturated sodium bicarbonate, extracted with diethyl ether (2x75 mL), and dried with sodium sulfate. Purification by flash chromatography (20% EtOAc in Hex) afforded a yellow oil (560 mg, 3.58 mmol, 74%). MS (ESI) m/z 157.1 [M+ 1]+. |