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Chemical Structure| 951122-32-0 Chemical Structure| 951122-32-0

Structure of 951122-32-0

Chemical Structure| 951122-32-0

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Product Details of [ 951122-32-0 ]

CAS No. :951122-32-0
Formula : C7H6FNO2
M.W : 155.13
SMILES Code : O=C(N)C1=CC(O)=CC=C1F

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Application In Synthesis of [ 951122-32-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 951122-32-0 ]

[ 951122-32-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 400-92-0 ]
  • [ 951122-32-0 ]
YieldReaction ConditionsOperation in experiment
82% With boron tribromide; In dichloromethane; at 20.0℃; for 48.0h; (Method H) Boron tribromide solution (1.0 M in CH2CI2, 23.6 ml, 23.6 mmol, 2 equiv.) was added slowly, dropwise to stirred solution of 2-fluoro-5- methoxybenzenecarboxamide (2.0 g, 11.8 mmol, 1 equiv.) in CH2CI2 (60 ml), at r.t., under N2. The reaction mixture was stirred at r.t. for 48 h. The solvent was removed under reduced pressure, the residue was dissolved in water (120 ml) and extracted with EtOAc (4x100 ml). The combined organic extracts were washed with water (2x100 ml), dried (Na2SO4) and filtered through a pad of silica gel. The filtrate was evaporated to dryness under reduced pressure, to give the desired compound as a grey solid (1.5O g, 82%).
 

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