Purity | Size | Price | VIP Price | USA Stock *1-2 Days | Global Stock *3-4 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
*Storage: {[proInfo.prStorage]}
CAS No. : | 953039-63-9 | MDL No. : | MFCD18382554 |
Formula : | C8H3BrClFN2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | - |
M.W : | 261.48 | Pubchem ID : | 59199299 |
Synonyms : |
|
TPSA :Topological Polar Surface Area | 25.8 | H-Bond Acceptor Count : | 3 |
XLogP3 : | 3.3 | H-Bond Donor Count : | 0 |
SP3 : | 0.00 | Rotatable Bond Count : | 0 |
Signal Word: | Warning | Class | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
![]() |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
89% | at 110℃; for 1.00 h; | Step 5. 8-Bromo-2-chloro-6-fluoroquinazolineA 0.5M suspension of 8-bromo-6-fluoroquinazolin-2-ol in phosphorus oxychloride was heated to 110 0C in an oil bath. The suspension was turned to a brown color solution in 20min. LCMS data showed that the reaction was complete after 1 h. The phosphorus oxychloride was removed by concentration. The residue was mixed with ice water, and adjusted pH to 7 by adding sodium bicarbonate. Reaction mixture was extracted with ethyl acetate. Combined organic phase was washed with water, brine, dried over sodium sulfate and concentrated to give desired product in 89percent yield. ES/MS m/z 261/263 (MH+). |
[ 174566-15-5 ]
2,4-Dichloro-7-fluoroquinazoline
Similarity: 0.71
[ 791602-75-0 ]
4-Chloro-5,7-difluoroquinazoline
Similarity: 0.61
[ 956100-62-2 ]
8-Bromo-2-chloroquinazolin-4-amine
Similarity: 0.79
[ 174566-15-5 ]
2,4-Dichloro-7-fluoroquinazoline
Similarity: 0.71
[ 956100-62-2 ]
8-Bromo-2-chloroquinazolin-4-amine
Similarity: 0.79
[ 956100-62-2 ]
8-Bromo-2-chloroquinazolin-4-amine
Similarity: 0.79
[ 174566-15-5 ]
2,4-Dichloro-7-fluoroquinazoline
Similarity: 0.71