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Chemical Structure| 955979-09-6 Chemical Structure| 955979-09-6

Structure of 955979-09-6

Chemical Structure| 955979-09-6

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Product Details of [ 955979-09-6 ]

CAS No. :955979-09-6
Formula : C15H20BNO2
M.W : 257.14
SMILES Code : CC1(C)C(C)(C)OB(C2=CC=C(C)C3=C2C=CN3)O1

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 955979-09-6 ]

[ 955979-09-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 936092-87-4 ]
  • [ 73183-34-3 ]
  • [ 955979-09-6 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate;(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 80℃; for 8h; To a suspension of 4-bromo-7-methylindole (349 mg, 1.66 mmol), bispinacolatodiboron (2.66 mmol, 674 mg) and potassium acetate (4.98 mmol, 489 mg) in DMSO (12 mL) was added Pd(dppf)2Cl2 (0.05 mmol, 41 mg). The mixture25 was degassed with argon and heated at 80 0C for 8 hours. The mixture was allowed to cool and partitioned between ether and water and the aqueous later extracted with ether. The combined organic layers were washed with brine, separated and dried. The crude product was purified by chromatography to yield 7-methyl-4-(4,4,5,5- tetramethyl-[l, 3,2]dioxaborolan-2-yl)-lH-indole as a' solid which was triturated in30 petrol giving a white crystalline solid (117 mg).
 

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