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[ CAS No. 96-20-8 ] {[proInfo.proName]}

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Chemical Structure| 96-20-8
Chemical Structure| 96-20-8
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Product Details of [ 96-20-8 ]

CAS No. :96-20-8 MDL No. :MFCD00008095
Formula : C4H11NO Boiling Point : -
Linear Structure Formula :- InChI Key :JCBPETKZIGVZRE-UHFFFAOYSA-N
M.W : 89.14 Pubchem ID :22129
Synonyms :

Safety of [ 96-20-8 ]

Signal Word:Danger Class:8
Precautionary Statements:P501-P280-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310 UN#:3267
Hazard Statements:H314 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 96-20-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 96-20-8 ]
  • Downstream synthetic route of [ 96-20-8 ]

[ 96-20-8 ] Synthesis Path-Upstream   1~16

  • 1
  • [ 2835-81-6 ]
  • [ 96-20-8 ]
  • [ 22621-37-0 ]
YieldReaction ConditionsOperation in experiment
90% With ammonium hydroxide In ethanol Production of (+)-2-Amino-1-butanol
EXAMPLE 9
1.8 g of L-2-aminobutyric acid as obtained in Example 5 was dispersed in 30 ml of ethanol and dry hydrogen chloride gas was bubbled through the dispersion until the L-2-aminobutyric acid was completely dissolved to form a homogeneous solution, and then the solution was refluxed for 4 hours.
After cooling, the ethanol was removed under reduced pressure.
The crystals obtained were dissolved by adding aqueous ammonia while cooling and then extracted with diethyl ether.
The extract was dried with magnesium sulfate and distilled under reduced pressure, and thus 2.0 g of a L-2-aminobutyric acid ethyl ester fraction (b.p. 66°-67°C/18 mm Hg) was obtained.
The yield was 90percent. (α)D27 = +17.8° +- 1° (C = 5.6, ethanol).
Reference: [1] Patent: US3979457, 1976, A,
  • 2
  • [ 609-31-4 ]
  • [ 96-20-8 ]
Reference: [1] Patent: US4924029, 1990, A,
[2] Patent: US4924029, 1990, A,
[3] Journal of Organic Chemistry, 1943, vol. 8, p. 11
[4] Journal of Organic Chemistry, 1943, vol. 8, p. 11
[5] Chem. Zentralbl., 1902, vol. 73, # I, p. 717
[6] Industrial and Engineering Chemistry, 1948, vol. 40, p. 507
[7] Tetrahedron, 1990, vol. 46, # 21, p. 7403 - 7412
[8] Tetrahedron, 1990, vol. 46, # 21, p. 7403 - 7412
  • 3
  • [ 193086-15-6 ]
  • [ 96-20-8 ]
Reference: [1] Tetrahedron Letters, 2010, vol. 51, # 39, p. 5131 - 5133
  • 4
  • [ 5339-83-3 ]
  • [ 96-20-8 ]
Reference: [1] Synthesis, 2003, # 13, p. 1965 - 1967
  • 5
  • [ 72784-43-1 ]
  • [ 96-20-8 ]
Reference: [1] Patent: EP3424928, 2019, A1,
  • 6
  • [ 2835-81-6 ]
  • [ 96-20-8 ]
Reference: [1] Monatshefte fuer Chemie, 1953, vol. 84, p. 1097
[2] Doklady Chemistry, 1972, vol. 203, p. 200 - 203[3] Dokl. Akad. Nauk SSSR Ser. Khim., 1972, vol. 203, p. 106 - 109
[4] Doklady Chemistry, 1972, vol. 203, p. 240 - 243[5] Dokl. Akad. Nauk SSSR Ser. Khim., 1972, vol. 203, p. 354 - 357
  • 7
  • [ 91028-76-1 ]
  • [ 96-20-8 ]
Reference: [1] Journal of the American Chemical Society, 1954, vol. 76, p. 1231,1233
  • 8
  • [ 860763-66-2 ]
  • [ 96-20-8 ]
Reference: [1] Annales de Chimie (Cachan, France), 1912, vol. <8>26, p. 270
  • 9
  • [ 7682-18-0 ]
  • [ 96-20-8 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979, p. 1230 - 1236
  • 10
  • [ 106-88-7 ]
  • [ 96-20-8 ]
  • [ 13552-21-1 ]
  • [ 584-03-2 ]
Reference: [1] Physical Chemistry Chemical Physics, 2018, vol. 20, # 3, p. 1583 - 1590
  • 11
  • [ 7062-04-6 ]
  • [ 96-20-8 ]
Reference: [1] Pharmaceutical Chemistry Journal, 1978, vol. 12, # 4, p. 491 - 493[2] Khimiko-Farmatsevticheskii Zhurnal, 1978, vol. 12, # 4, p. 77 - 79
  • 12
  • [ 153363-52-1 ]
  • [ 96-20-8 ]
Reference: [1] Gazzetta Chimica Italiana, 1993, vol. 123, # 10, p. 549 - 552
  • 13
  • [ 7647-01-0 ]
  • [ 860763-66-2 ]
  • [ 96-20-8 ]
Reference: [1] Annales de Chimie (Cachan, France), 1912, vol. <8>26, p. 270
  • 14
  • [ 96-20-8 ]
  • [ 5856-63-3 ]
Reference: [1] Synthesis, 2003, # 13, p. 1965 - 1967
[2] Journal of the American Chemical Society, 1954, vol. 76, p. 2801
[3] Acta Chemica Scandinavica (1947-1973), 1962, vol. 16, p. 71 - 77
[4] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1961, vol. 253, p. 2704 - 2705
[5] Journal of Heterocyclic Chemistry, 1970, vol. 7, p. 1407 - 1411
  • 15
  • [ 96-20-8 ]
  • [ 5856-63-3 ]
  • [ 5856-62-2 ]
Reference: [1] Patent: WO2010/148191, 2010, A2, . Location in patent: Page/Page column 45-49; 59
[2] New Journal of Chemistry, 2013, vol. 37, # 12, p. 4018 - 4024
  • 16
  • [ 96-20-8 ]
  • [ 18162-48-6 ]
  • [ 811841-81-3 ]
Reference: [1] Journal of the American Chemical Society, 2018, vol. 140, # 16, p. 5322 - 5325
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