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Chemical Structure| 98581-86-3 Chemical Structure| 98581-86-3

Structure of 98581-86-3

Chemical Structure| 98581-86-3

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Product Details of [ 98581-86-3 ]

CAS No. :98581-86-3
Formula : C8H7N3O
M.W : 161.16
SMILES Code : OC1=CC=C(N2C=NN=C2)C=C1
MDL No. :MFCD11855617

Safety of [ 98581-86-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 98581-86-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 98581-86-3 ]

[ 98581-86-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 628-36-4 ]
  • [ 123-30-8 ]
  • [ 98581-86-3 ]
YieldReaction ConditionsOperation in experiment
With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; toluene; for 3h;Reflux; 4-amnophenol (1 g, 9.16 mmol) and bisformyl hydrazine (888 mg, 10.08 mmol) were dissolved in a mixture of toluene (30 niL) and DMF (3 mL), followed by addition of pTSA (1.92 g, 10.08 mmol). The mixture was heated under reflux for 3 hours. Upon cooling, the mixture separated to two layers. The upper toluene layer was discarded. The lower dark DMF layer was directly purified by column chromatography using a 115 gram biotage siica gel cartridge eluting with 20-40 ethyl acetate / hexanes (gradient) to give the product as pale yellow solid. LRMS calc: 161.1; obs: 162.4 (M+ 1).
 

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