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Chemical Structure| 173606-50-3 Chemical Structure| 173606-50-3
Chemical Structure| 173606-50-3

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Boc-10-Aminodecanoic acid is an amino acid derivative with a decanoic acid backbone and a Boc-protected amine group, used in peptide synthesis.

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Product Details of Boc-10-Aminodecanoic acid

CAS No. :173606-50-3
Formula : C15H29NO4
M.W : 287.40
SMILES Code : O=C(O)CCCCCCCCCNC(OC(C)(C)C)=O
MDL No. :MFCD00270351
InChI Key :DUNPXMOBBKBKHK-UHFFFAOYSA-N
Pubchem ID :4321832

Safety of Boc-10-Aminodecanoic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of Boc-10-Aminodecanoic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 173606-50-3 ]

[ 173606-50-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13108-19-5 ]
  • [ 24424-99-5 ]
  • [ 173606-50-3 ]
YieldReaction ConditionsOperation in experiment
2.42 g With sodium hydroxide; In water; tert-butyl alcohol; at 20℃; for 24h; The crude product from the previous step was placed in a 100-mL round-bottom flask with a magnetic stirbar, and NaOH (505 mg, 12.6 mmol) and Boc anhydride (2.31 g, 10.6 mmol) were added. Water (11 mL) and t-butanol (5 mL) were added to the flask to dissolve the solids, and the mixture was stirred at rt for 24 h. The crude product was diluted with water (20 mL) and 1 M HCl (20 mL). The resulting mixture was extracted with ethyl acetate (30 mL, 2x) and brine (30 mL). The organic layer was isolated, dried over MgSO4, and concentrated in vacuo to yield 2.42 g of 2 as a white solid (84percent isolated yield). The 1H NMR and 13C NMR spectra for acid 2 were identical to those that were previously reported.
 

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