*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Chromone is a natural compound with various biological activities, including antioxidant, anti-inflammatory, and antibacterial properties. It is studied as a potential drug scaffold in drug development.
4.5
*For Research Use Only !
Change View
Size | Price | VIP Price | US Stock |
Global Stock |
In Stock | ||
{[ item.pr_size ]} |
Inquiry
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.discount_usd) ]} {[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} |
Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]} | Inquiry {[ item.pr_usastock ]} In Stock Inquiry - | {[ item.pr_chinastock ]} {[ item.pr_remark ]} In Stock 1-2 weeks - Inquiry - | Login | - + | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
1-2weeks
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price, item.pr_usd) ]}
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
In Stock
- +
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 491-38-3 |
Formula : | C9H6O2 |
M.W : | 146.14 |
SMILES Code : | O=C1C=COC2=CC=CC=C12 |
MDL No. : | MFCD00024064 |
InChI Key : | OTAFHZMPRISVEM-UHFFFAOYSA-N |
Pubchem ID : | 10286 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319 |
Precautionary Statements: | P261-P305+P351+P338 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
89% | With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; benzoic acid; silver(I) triflimide; In neat (no solvent); at 80℃; for 6.5h; | At room temperature, chromone (0.2 mmol), N-ethylmaleimide (0.5 mmol), [Ru (p-cymene) Cl2] 2 (2.5mol%), AgNTf2 ( 10mol%), benzoic acid (0.8equiv.). Warm to 80 C and stir. TLC tracking detection reaction. After 6.5 hours, the reaction was stopped. Water and ethyl acetate were added to the reaction system, the organic layer was separated, and the aqueous layer was washed three times with ethyl acetate. All organic layers were combined, dried over anhydrous sodium sulfate, concentrated, and separated by column chromatography (40% ethyl acetate petroleum ether solution) to obtain the product 70.8mg, yield 89% |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | With 1,4-dihydropyridine; diphenyl hydrogen phosphate; 5,6-bis(5-methoxythiophen-2-yl)pyrazine-2,3-dicarbonitrile; In acetonitrile; at -78 - 25℃; for 8.0h;Schlenk technique; Inert atmosphere; Irradiation; Green chemistry; | General procedure: Take a dry 25 mL schlenk tube and add 87.6 mg (0.6 mmol) chromone I-1, 42.0 mg (0.4 mmol) vinylpyridine II-1, DPZ (2.8 mg, 0.008 mmol), diphenyl phosphate (20 mg, 0.08 mmol), 1,4-dihydropyridine (HZE, 182 mg, 0.72 mmol), then add 8 mL of toluene, cap the bottle, and degas with a vacuum pump at no higher than -78C 2-3 times, 5-10 minutes each time, pass in argon gas for protection, then place it at 25, irradiate it with a 3 W blue light with a wavelength of 410-510 nm at a distance of about 3 cm from the schlenk tube, and react for 8 hours. After the reaction is over, column chromatography (petroleum ether/ethyl acetate = 10~2:1, volume ratio), rotary evaporation and concentration, vacuum drying (drying at 25C for 1 hour) to obtain 83.0 mg of yellow oil 2- The yield of (2-(pyridin-2-yl)ethyl)chroman-4-one III-1 was 82%. |