Gamma-glutamylcysteine is a dipeptide containing cysteine and glutamic acid, serving as a precursor to glutathione (GSH). It acts as a cofactor for glutathione peroxidase (GPx) to increase GSH levels.

Synonyms: γ-Glu-Cys

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Quality Control of Gamma-glutamylcysteine Purity: 95% SDS Specification

COA

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Batch number can be found on the product's label following the word 'Batch'.

NMR

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CNMR

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HPLC

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LC-MS

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Product Details of Gamma-glutamylcysteine

CAS No. :	636-58-8
Formula :	C₈H₁₄N₂O₅S
M.W :	250.27
SMILES Code :	O=C(O)[C@@H](N)CCC(N[C@H](C(O)=O)CS)=O
Synonyms :	γ-Glu-Cys
MDL No. :	MFCD00237863

Safety of Gamma-glutamylcysteine

GHS Pictogram:
Signal Word:	Danger
Hazard Statements:	H302-H319-H332-H372-H400
Precautionary Statements:	P260-P264-P270-P273-P280-P301+P312+P330-P304+P312-P305+P351+P338-P314-P337+P313-P391-P501
Class:	9
UN#:	3077
Packing Group:	Ⅲ

Application In Synthesis of Gamma-glutamylcysteine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 636-58-8 ]

[ 636-58-8 ] Synthesis Path-Downstream 1~47

1
[ 636-58-8 ]
[ 23052-19-9 ]

References: [1]Biochemical Journal,1935,vol. 29,p. 1602,1605.
[2]Journal of Mass Spectrometry,2006,vol. 41,p. 1578 - 1593.
[3]Inorganic Chemistry,2011,vol. 50,p. 72 - 85.

2
[ 23052-19-9 ]
[ 636-58-8 ]

References: [1]Glutathione Symp. 1953 S.82,.

3
[ 4510-09-2 ]
[ 953-18-4 ]
[ 636-58-8 ]

References: [1]Journal of Biological Chemistry,1952,vol. 199,p. 407 - 414.

4
[ 100051-89-6 ]
[ 636-58-8 ]

References: [1]Journal of the American Chemical Society,1958,vol. 80,p. 1158,1162.

5
[ 636-58-8 ]
[ 56-40-6 ]
[ 70-18-8 ]

References: [1]D.M.Greenberg, Metabolic Pathways,Bd.2 <New York 1961>S.253,.
[2]Journal of labelled compounds and radiopharmaceuticals,2010,vol. 53,p. 110 - 112.
[3]Journal of the American Chemical Society,2014,vol. 136,p. 11566 - 11569.

6
[ 52-90-4 ]
[ 142-47-2 ]
[ 636-58-8 ]

References: [1]Agricultural and Biological Chemistry,1981,vol. 45,p. 2839 - 2846.
[2]Biochemical Journal,2013,vol. 449,p. 783 - 794.

7
[ 95014-75-8 ]
[ 636-58-8 ]

References: [1]Tetrahedron Letters,1984,vol. 25,p. 3869 - 3872.

8
[ 636-58-8 ]
[ 108-24-7 ]
N,S-bis-acetyl-γ-L-glutamyl-L-cysteine [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 1676 - 1681.

9
[ 190063-00-4 ]
[ 636-58-8 ]

References: [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 1676 - 1681.

10
[ 636-58-8 ]
[ 507-09-5 ]
N,S-bis-acetyl-γ-L-glutamyl-L-cysteine [ No CAS ]
(S)-4-((R)-2-Acetylsulfanyl-1-carboxy-ethylcarbamoyl)-2-amino-butyric acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 1676 - 1681.

11
[ 70-18-8 ]
[ 636-58-8 ]
[ 86220-45-3 ]
[ 95014-75-8 ]
[ 100922-53-0 ]
[ 118433-03-7 ]

References: [1]Bioscience, Biotechnology and Biochemistry,1996,vol. 60,p. 1193 - 1194.

14
[ 52-90-4 ]
L-glutamate [ No CAS ]
[ 636-58-8 ]

References: [1]Agricultural and Biological Chemistry,1988,vol. 52,p. 2633 - 2634.

15
N-<L-4-benzyloxycarbonylamino-4-methoxycarbonyl-butyryl->-L-cysteine ethyl ester [ No CAS ]
[ 636-58-8 ]

References: [1]Biochemical Journal,1935,vol. 29,p. 1602,1605.

16
[ 56-41-7 ]
[ 70-18-8 ]
[ 636-58-8 ]
[ 34286-34-5 ]

References: [1]Bioscience, Biotechnology and Biochemistry,2003,vol. 67,p. 434 - 437.

17
[ 56-45-1 ]
[ 70-18-8 ]
[ 636-58-8 ]
γ-L-glutamyl-L-cysteinyl-L-serine [ No CAS ]

References: [1]Bioscience, Biotechnology and Biochemistry,2003,vol. 67,p. 434 - 437.

18
[ 636-58-8 ]
[ 50700-49-7 ]
3-(γ-L-glutamyl-L-cystein-S-yl)acetaminophen [ No CAS ]

References: [1]Journal of Pharmacology and Experimental Therapeutics,2000,vol. 294,p. 735 - 745.

19
[ 636-58-8 ]
[ 556-50-3 ]
[ 52-90-4 ]

References: [1]Bioscience, Biotechnology and Biochemistry,2006,vol. 70,p. 369 - 376.

20
(R)-3-[(S)-4-Carboxy-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyryl]-2-methyl-thiazolidine-4-carboxylic acid [ No CAS ]
[ 636-58-8 ]

References: [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 1676 - 1681.

21
[ 25830-77-7 ]
[ 636-58-8 ]

References: [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 1676 - 1681.
[2]Journal of the American Chemical Society,1958,vol. 80,p. 1158,1162.

22
[ 27025-41-8 ]
[ 636-58-8 ]

References: [1]Biochemical Preparations,1962,vol. 9,p. 53.

23
[ 52-90-4 ]
[ 142-47-2 ]
[ 636-58-8 ]

References: [1]Bioscience, Biotechnology and Biochemistry,2009,vol. 73,p. 2677 - 2683.

24
[ 636-58-8 ]
[ 70-18-8 ]
N,N'-bis-γ-glutamylcystinylglycine [ No CAS ]

References: [1]Inorganic Chemistry,2011,vol. 50,p. 72 - 85.

25
[ 52-90-4 ]
glutamate [ No CAS ]
[ 636-58-8 ]

References: [1]Journal of Biological Chemistry,2010,vol. 285,p. 14459 - 14466.

26
[ 636-58-8 ]
[ 56-39-3 ]
[ 1234937-76-8 ]

References: [1]Journal of labelled compounds and radiopharmaceuticals,2010,vol. 53,p. 110 - 112.

27
[ 636-58-8 ]
[ 56-39-3 ]
[ 1234937-73-5 ]
[ 1234937-76-8 ]

References: [1]Journal of labelled compounds and radiopharmaceuticals,2010,vol. 53,p. 110 - 112.

28
[ 636-58-8 ]
[ 56-39-3 ]
[ 1234937-73-5 ]

References: [1]Journal of labelled compounds and radiopharmaceuticals,2010,vol. 53,p. 110 - 112.

29
[ 636-58-8 ]
[ 7149-49-7 ]
[ 169136-26-9 ]

References: [1]Journal of Inclusion Phenomena and Macrocyclic Chemistry,2010,vol. 66,p. 409 - 416.

30
[ 636-58-8 ]
[ 643-79-8 ]
[ 1282511-37-8 ]

References: [1]Journal of Inclusion Phenomena and Macrocyclic Chemistry,2010,vol. 66,p. 409 - 416.

31
[ 636-58-8 ]
[ 71-00-1 ]
C₁₄H₂₁N₅O₈S [ No CAS ]

References: [1]Organic Letters,2013,vol. 15,p. 4854 - 4857.

32
[ 636-58-8 ]
[ 534-30-5 ]
C₁₇H₂₇N₅O₈S [ No CAS ]