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Chemical Structure| 16741-80-3 Chemical Structure| 16741-80-3
Chemical Structure| 16741-80-3

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Synonyms: H-Cys(Bzl)-OMe.HCl

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Product Details of H-Cys(Bzl)-OMe·HCl

CAS No. :16741-80-3
Formula : C11H16ClNO2S
M.W : 261.77
SMILES Code : O=C(OC)[C@@H](N)CSCC1=CC=CC=C1.[H]Cl
Synonyms :
H-Cys(Bzl)-OMe.HCl
MDL No. :MFCD00034845
InChI Key :QVJDVOZRQMIIHP-PPHPATTJSA-N
Pubchem ID :45073222

Safety of H-Cys(Bzl)-OMe·HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of H-Cys(Bzl)-OMe·HCl

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 16741-80-3 ]

[ 16741-80-3 ] Synthesis Path-Downstream   1~39

  • 1
  • [ 103-82-2 ]
  • [ 16741-80-3 ]
  • <i>S</i>-benzyl-<i>N</i>-phenylacetyl-L-cysteine methyl ester [ No CAS ]
  • 3
  • [ 35726-62-6 ]
  • [ 16741-80-3 ]
  • <i>N</i>-(<i>O</i>-ethyl-<i>N</i>-benzyloxycarbonyl-L-α-glutamyl)-<i>S</i>-benzyl-L-cysteine methyl ester [ No CAS ]
  • 5
  • [ 75-44-5 ]
  • [ 16741-80-3 ]
  • N-Carbonyl-S-benzyl-L-cystein-methylester [ No CAS ]
  • 8
  • [ 6398-06-7 ]
  • [ 16741-80-3 ]
  • [ 105091-47-2 ]
  • 9
  • [ 2304-98-5 ]
  • [ 16741-80-3 ]
  • [ 106506-91-6 ]
  • 10
  • [ 4703-32-6 ]
  • [ 16741-80-3 ]
  • [ 96113-81-4 ]
  • 11
  • [ 94430-73-6 ]
  • [ 16741-80-3 ]
  • [ 105002-40-2 ]
  • 12
  • [ 16741-80-3 ]
  • [ 2592-18-9 ]
  • Boc-D-Thr-Cys(S-Bzl)-OCH3 [ No CAS ]
  • 13
  • [ 16741-80-3 ]
  • (S)-4-Benzyloxycarbonylamino-4-ethylsulfanylcarbonyl-butyric acid; compound with dicyclohexyl-amine [ No CAS ]
  • Carbobenzoxy-L-glutamyl-1-thioethylester-5-(S-benzyl)-L-cystein-methylester [ No CAS ]
  • 14
  • [ 16741-80-3 ]
  • [ 98-88-4 ]
  • [ 16359-17-4 ]
  • 15
  • [ 16741-80-3 ]
  • [ 141-75-3 ]
  • [ 62309-95-9 ]
  • 16
  • [ 17360-25-7 ]
  • [ 16741-80-3 ]
  • Tos-L-Val-L-Cys(Bzl)-OMe [ No CAS ]
  • 17
  • [ 1220-80-0 ]
  • [ 16741-80-3 ]
  • Tos-L-Leu-L-Cys(Bzl)-OMe [ No CAS ]
  • 19
  • [ 4703-34-8 ]
  • [ 16741-80-3 ]
  • Tos-Gly-Gly-L-Cys(Bzl)-OMe [ No CAS ]
  • 20
  • [ 4703-36-0 ]
  • [ 16741-80-3 ]
  • Tos-L-Cys(Bzl)-L-Cys(Bzl)-OMe [ No CAS ]
  • 21
  • [ 1465-10-7 ]
  • [ 16741-80-3 ]
  • N,N'-bis(Tos)-L-(Cys)2-<L-Cys(Bzl)-OMe>2 [ No CAS ]
  • 22
  • [ 16741-80-3 ]
  • [ 84015-44-1 ]
  • Tos-Gly-Gly-Gly-L-Cys(Bzl)-OMe [ No CAS ]
  • 23
  • [ 16741-80-3 ]
  • [ 91889-77-9 ]
  • [ 113756-86-8 ]
  • 24
  • [ 16741-80-3 ]
  • [ 1080-44-0 ]
  • Tos-Gly-L-Cys(Bzl)-OMe [ No CAS ]
  • 25
  • [ 16741-80-3 ]
  • [ 100-52-7 ]
  • [ 67628-14-2 ]
  • 26
  • [ 16741-80-3 ]
  • [ 1138-80-3 ]
  • [ 5908-08-7 ]
  • 27
  • [ 2018-66-8 ]
  • [ 16741-80-3 ]
  • [ 18791-59-8 ]
  • 28
  • [ 5105-78-2 ]
  • [ 16741-80-3 ]
  • (R)-2-(4-Benzyloxycarbonylamino-butyrylamino)-3-benzylsulfanyl-propionic acid [ No CAS ]
  • 29
  • [ 26607-51-2 ]
  • [ 16741-80-3 ]
  • (R)-2-((R)-2-Benzyloxycarbonylamino-propionylamino)-3-benzylsulfanyl-propionic acid [ No CAS ]
  • 30
  • [ 1685-33-2 ]
  • [ 16741-80-3 ]
  • (R)-2-((R)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-benzylsulfanyl-propionic acid methyl ester [ No CAS ]
  • 31
  • [ 1149-26-4 ]
  • [ 16741-80-3 ]
  • [ 16088-40-7 ]
  • 32
  • [ 28862-79-5 ]
  • [ 16741-80-3 ]
  • (R)-2-((R)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-3-benzylsulfanyl-propionic acid [ No CAS ]
  • 34
  • [ 2448-45-5 ]
  • [ 16741-80-3 ]
  • [ 17563-27-8 ]
  • 35
  • [ 16741-80-3 ]
  • [ 501-53-1 ]
  • [ 94311-65-6 ]
  • 36
  • [ 67-56-1 ]
  • [ 3054-01-1 ]
  • [ 16741-80-3 ]
YieldReaction ConditionsOperation in experiment
100% With hydrogenchloride; at 0 - 20℃; Example 1 Synthesis OFN (L-CYANOCYCLOPROPYL)-3-PHENYLMETHANESULFONYL-2 (R)- (2, 2, 2-TRIFLUORO-1 (RS)- thiophen-2-yl-ethylamino) propionamide STEP 1 To a COLD (0 C), stirred solution of 2 (R)-amino-3-phenylmethanesulfanylpropionic acid (commercially available) (4. 01 g, 19.0 mmol) in methanol (100 mL) was introduced HCL gas for 15 min and the reaction mixture was sealed and stirring was continued at rt overnight. The solvent was then evaporated under vacuum to give methyl 2 (R)-amino-3-phenylmethane- sulfanylpropionate HCL in quantitative yield (4.98 g).
85% With thionyl chloride; at 0 - 20℃; for 6h; To a solution of compound 7 (1 g, 5 mmol) in methanol (30 mL) at 0 C was dropped SOCl2 (1.5 mL, 7 mmol) and then the mixture was stirred at room temperature for 6 h. Methanol was evaporated to give 8 as a white solid (1.3 g, 85%), mp 148-150 C (lit [37].: 160-162 C; lit. [38].: 151-152 C). 1H NMR (400 MHz, CDCl3) delta 7.23-7.32 (m, 5H, Ar-H), 3.73 (s, 2H, -CH2Ph), 3.72 (s, 3H, -COOCH3), 3.58-3.61 (m, 1H, H-2), 2.80-2.85 (m, 1H, H-3), 2.64-2.69 (m, 1H, H-3).
  • 39
  • [ 16741-80-3 ]
  • [ 170787-77-6 ]
  • [ 328236-07-3 ]
 

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