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Chemical Structure| 617-68-5 Chemical Structure| 617-68-5
Chemical Structure| 617-68-5

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H-DL-Lys-OH·2HCl is a lysine derivative, commonly used in protein synthesis and amino acid metabolism studies, involved in regulating amino acid metabolism and supporting cell growth.

4.5 *For Research Use Only !

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Product Details of H-DL-Lys-OH·2HCl

CAS No. :617-68-5
Formula : C6H16Cl2N2O2
M.W : 219.11
SMILES Code : NC(CCCCN)C(O)=O.[H]Cl.[H]Cl
MDL No. :MFCD00037587
InChI Key :JBBURJFZIMRPCZ-UHFFFAOYSA-N
Pubchem ID :517175

Safety of H-DL-Lys-OH·2HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of H-DL-Lys-OH·2HCl

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 617-68-5 ]

[ 617-68-5 ] Synthesis Path-Downstream   1~11

  • 1
  • [ 67-56-1 ]
  • [ 617-68-5 ]
  • DL-lysine methyl ester [ No CAS ]
  • 2
  • [ 85235-51-4 ]
  • [ 617-68-5 ]
  • 3
  • [ 77300-38-0 ]
  • [ 617-68-5 ]
  • 4
  • [ 29512-97-8 ]
  • [ 617-68-5 ]
  • 5
  • [ 17687-54-6 ]
  • [ 617-68-5 ]
  • 7
  • [ 4254-76-6 ]
  • [ 617-68-5 ]
  • 8
  • [ 77300-44-8 ]
  • [ 617-68-5 ]
  • 9
  • [ 64-17-5 ]
  • [ 617-68-5 ]
  • ethyl 2,6-diaminohexanoate dihydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
11.9 g of thionyl chloride are added in the cold to L-<strong>[617-68-5]lysine hydrochloride</strong> (11 g) in 100 ml of ethanol and the mixture is refluxed for 3 h. After evaporation of the excess thionyl chloride and ethanol, the product is washed with heptane and then dried under vacuum to give 14.8 g of <strong>[617-68-5]lysine bishydrochloride</strong> in which the acid group is esterified with ethanol. This product (4.9 g) is reacted with 7 g of the N-hydroxysuccinimide derivative of palmitic acid (Rn Cas 14464-31-4, available from Sigma) in an acetone/water mixture (80+40 ml respectively), in the presence of 7 g of triethylamine. After one night at room temperature, the product is precipitated by adding 1 N hydrochloric acid. After purification by passage over a silica column, 3.3 g of the desired product are recovered. Its structure is confirmed by NMR spectroscopy.
  • 10
  • [ 10098-89-2 ]
  • [ 617-68-5 ]
YieldReaction ConditionsOperation in experiment
With thionyl chloride; In ethanol; for 3.0h;Heating / reflux; 11.9 g of thionyl chloride are added in the cold to L-lysine hydrochloride (11 g) in 100 ml of ethanol and the mixture is refluxed for 3 h. After evaporation of the excess thionyl chloride and ethanol, the product is washed with heptane and then dried under vacuum to give 14.8 g of lysine bishydrochloride in which the acid group is esterified with ethanol. This product (4.9 g) is reacted with 7 g of the N-hydroxysuccinimide derivative of palmitic acid (Rn Cas 14464-31-4, available from Sigma) in an acetone/water mixture (80+40 ml respectively), in the presence of 7 g of triethylamine. After one night at room temperature, the product is precipitated by adding 1 N hydrochloric acid. After purification by passage over a silica column, 3.3 g of the desired product are recovered. Its structure is confirmed by NMR spectroscopy.
  • 11
  • Reinecke salt [ No CAS ]
  • [ 617-68-5 ]
  • lysiniumtetrathiocyanatodiamminechromate(III) * 4 H2O [ No CAS ]
 

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