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Chemical Structure| 5617-32-3 Chemical Structure| 5617-32-3
Chemical Structure| 5617-32-3

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Heptaethylene glycol is a PEG-based PROTAC linker employed in the synthesis of PROTAC molecules.

Synonyms: HO-PEG7-OH

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Product Citations

Product Citations

Olutobi Daniel Ogunbiyi ; Luciana Teresa Dias Cappelini ; Mymuna Monem ; Emily Mejias ; Florence George ; Piero Gardinali , et al.

Abstract: Environmental contamination through direct contact, ingestion and inhalation are common routes of children’s exposure to chemicals, in which through indoor and outdoor activities associated with common hand-to-mouth, touching objects, and behavioral tendencies, children can be susceptible and vulnerable to organic contaminants in the environment. The objectives of this study were the screening and identification of a wide range of organic contaminants in indoor dust, soil, food, drinking water, and urine matrices (N = 439), prioritizing chemicals to assess children’s environmental exposure, and selection of unique tracers of soil and dust ingestion in young children by non-targeted analysis (NTA) using Q-Exactive Orbitrap followed data processing by the Compound Discoverer (v3.3, SP2). Chemical features were first prioritized based on their predominant abundance (peak area>500,000), detection frequency (in >50% of the samples), available information on their uses and potential toxicological effects. Specific tracers of soil and dust exposure in children were selected in this study including Tripropyl and . The criteria for selection of the tracers were based on their higher abundance, detection frequency, unique functional uses, measurable amounts in urine (suitable biomarker), and with information on gastrointestinal absorption, metabolism, and excretion, and were further confirmed by authentic standards. We are proposing for the first time suitable unique tracers for dust ingestion by children.

Keywords: NTA ; Chemical prioritization ; Soil and dust ingestion ; Environmental exposure ; Florida

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Product Details of Heptaethylene glycol

CAS No. :5617-32-3
Formula : C14H30O8
M.W : 326.38
SMILES Code : OCCOCCOCCOCCOCCOCCOCCO
Synonyms :
HO-PEG7-OH
MDL No. :MFCD00002876
InChI Key :XPJRQAIZZQMSCM-UHFFFAOYSA-N
Pubchem ID :79718

Safety of Heptaethylene glycol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Heptaethylene glycol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5617-32-3 ]
 

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