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Chemical Structure| 102767-28-2 Chemical Structure| 102767-28-2

Structure of Levetiracetam
CAS No.: 102767-28-2

Chemical Structure| 102767-28-2

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Levetiracetam is an anticonvulsant with antihyperalgesic efficacy in inflammatory pain. It binds the synaptic vesicle protein SV2A (pIC50 = 5.7), presumably altering vesicle exocytosis.

Synonyms: UCB L059; SIB-S1; Levetiracetam, Keppra, Etiracetam, UCB 6474

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Product Details of Levetiracetam

CAS No. :102767-28-2
Formula : C8H14N2O2
M.W : 170.21
SMILES Code : CC[C@H](N1CCCC1=O)C(N)=O
Synonyms :
UCB L059; SIB-S1; Levetiracetam, Keppra, Etiracetam, UCB 6474
MDL No. :MFCD03265610
InChI Key :HPHUVLMMVZITSG-LURJTMIESA-N
Pubchem ID :5284583

Safety of Levetiracetam

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338

Related Pathways of Levetiracetam

RTK

Isoform Comparison

Biological Activity

Target
  • Calcium Channel

In Vitro:

Cell Line
Concentration Treated Time Description References
Spinal cord neurons 100 μM 25 seconds At 100 μM, LEV had no effect on the amplitude or desensitization time constant of glycine-induced currents. Br J Pharmacol. 2002 Jul;136(5):659-72.
Hippocampal neurons 100 μM 25 seconds At 100 μM, LEV significantly reduced the peak amplitude of GABA-induced currents (78.2% of control) but had a lesser effect on the desensitization of GABA currents (134.2% of control). Br J Pharmacol. 2002 Jul;136(5):659-72.
Cerebellar granule neurons 100 μM 25 seconds At 100 μM, LEV marginally but significantly affected the peak amplitude of the current induced by 50 μM GABA and slowed the decay phase (desensitization). Br J Pharmacol. 2002 Jul;136(5):659-72.

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Mice Alzheimer's disease model mice Subcutaneous injection 75 mg/kg/d Continuous for 28 days LEV effectively reduced abnormal spike activity in hAPP mice, reversed hippocampal remodeling, behavioral abnormalities, synaptic dysfunction, and deficits in learning and memory. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2895-903
Mice Sound-induced clonic convulsions model Intraperitoneal injection 17 mg/kg Single dose, 30 minutes before testing LEV significantly suppressed sound-induced clonic convulsions. This protective effect was significantly abolished by co-administration of the β-carboline FG 7142 (10 mg/kg), while the benzodiazepine receptor antagonist flumazenil (5 mg/kg) had no effect. Br J Pharmacol. 2002 Jul;136(5):659-72.
ICR mice Not specified Intraperitoneal injection 1, 3, 10, 30, 100 and 300 mg kg-1 Twice daily for 5 days Investigated the effects of Levetiracetam on glutamine synthetase activity in mouse brain, showing no significant effect after single or repeated administration. Br J Pharmacol. 1999 Apr;126(7):1634-8
Mice Sepsis model (CLP) Intraperitoneal injection 300 mg/kg Every 12 hours for 48 hours Prevention of post-sepsis anxiety and PTSD-like fear expression Brain. 2022 May 24;145(4):1391-1409
Mice STXBP1-encephalopathy model Intraperitoneal injection 50 mg/kg Once daily for 5 days To evaluate the effect of the antiepileptic drug levetiracetam on epileptic-like activity and EEG abnormalities in STXBP1-encephalopathy model mice. Results showed that levetiracetam significantly reduced spike-wave discharges. Brain. 2018 May 1;141(5):1350-1374
Mice IL18KO/APP/PS1 mouse model Oral 1.8 mg/mL Daily for 8 weeks Levetiracetam almost completely prevented death in IL18KO/APP/PS1 mice Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):9002-9007
Transgenic APP mice (line J20) Alzheimer's disease model Intraperitoneal injection and subcutaneous micro-osmotic pump 75 mg/kg 3 times per day for 2 weeks; or continuously for 4 weeks via micro-osmotic pumps To evaluate the effects of Levetiracetam on neurogenesis and spatial discrimination, showing that treatment restored neurogenesis dynamics and improved spatial discrimination Cell Rep. 2019 Jun 25;27(13):3741-3751.e4

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01392768 Epilepsy Part... More >>ial Seizures Less << Phase 3 Completed - -
NCT00413296 Post-Traumatic Stress Disorder Phase 2 Phase 3 Completed - United States, North Carolina ... More >> Duke University Medical Center Durham, North Carolina, United States, 27705 Less <<
NCT00826865 Seizures COMPLETED 2025-08-05 MDS Pharma Services, Phoenix, ... More >>Arizona, 85044, United States Less <<
NCT00827320 Seizures COMPLETED 2025-06-07 Novum Pharmaceutical Research ... More >>Services, Houston, Texas, 77042, United States Less <<
NCT01150331 Status; Epilepticus, Tonic-clo... More >>nic Less << Phase 3 Completed - France ... More >> Necker Hospital Paris, France, 75015 Less <<
NCT00150787 Epilepsy, Tonic-clonic Phase 3 Completed - -
NCT00620165 Essential Tremor Phase 1 Phase 2 Completed - United States, California ... More >> VA Long Beach Healthcare System Long Beach, California, United States, 90822 Less <<
NCT00826722 Seizures COMPLETED 2025-06-07 Novum Pharmaceutical Research ... More >>Services, Houston, Texas, 77042, United States Less <<
NCT00629889 Brain and Central Nervous Syst... More >>em Tumors Seizure Less << Phase 2 Completed - Switzerland ... More >> Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland, CH-1011 USZ Zürich, Switzerland, CH-8091 Less <<
NCT01954121 Epilepsy Part... More >>ial Seizures Less << Phase 3 Completed - China ... More >> 13 Beijing, China 16 Changchun City, China 10 Chengdu, China 5 Chengdu, China 4 Chongqing, China 26 Guangzhou City, China 11 Guangzhou, China 1 Guangzhou, China 20 Guangzhou, China 24 Hangzhou, China 22 Harbin, China 29 Kunming, China 23 Nanjing City, China 6 Nanjing City, China 8 Nanjing City, China 21 Nanjing, China 27 Qingdao, China 14 Shanghai, China 15 Shanghai, China 18 Shanghai, China 2 Shanghai, China 19 Shijiazhuang, China 3 Suzhou, China 9 Taiyuan, China 25 Tianjin, China 12 Wuhan, China 7 Xi'an, China 17 Xian, China Less <<
NCT00160576 Idiopathic Parkinson Disease PHASE2 COMPLETED 2025-11-04 -
NCT00150735 Generalized Epilepsy Phase 3 Completed - -
NCT03048084 Glioma Phase 4 Recruiting February 1, 2022 Netherlands ... More >> VU University Medical Center Not yet recruiting Amsterdam, Netherlands, 1007 MB Contact: Jaap C Reijneveld, MD, PhD    0031204442834    jc.reijneveld@vumc.nl    Leiden University Medical Center Recruiting Leiden, Netherlands, 2333 ZA Contact: Johan AF Koekkoek, MD, PhD    0031715269111    j.a.f.koekkoek@lumc.nl    Erasmus Medical Center Not yet recruiting Rotterdam, Netherlands, 3008 AE Contact: Martin J van den Bent, MD, PhD    0031107040704    m.vandenbent@erasmusmc.nl    Haaglanden Medical Center Recruiting The Hague, Netherlands, 2501 CK Contact: Martin JB Taphoorn, MD, PhD    0031703302000    m.taphoorn@haaglandenmc.nl Less <<
NCT00826787 Seizures COMPLETED 2025-08-05 MDS Pharma Services, Phoenix, ... More >>Arizona, 85044, United States Less <<
NCT00849485 - Completed - -
NCT00849862 Healthy Phase 1 Completed - Canada, Quebec ... More >> SFBC-Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Less <<
NCT00859430 Healthy Phase 1 Completed - United States, Texas ... More >> CEDRA Clinical Research, LLC San Antonio, Texas, United States, 78217 Less <<
NCT01954121 - Completed - -
NCT00849862 - Completed - -
NCT00160654 Epilepsy, Partial PHASE4 COMPLETED 2006-12-12 N01036 808, Hong Kong, Hong Ko... More >>ng|N01036 842, Hong Kong, Hong Kong|N01036 815, Kwun Tong, Hong Kong|N01036 811, Kuala Lumpur, Malaysia|N01036 812, Kuala Lumpur, Malaysia|N01036 813, Kuala Lumpur, Malaysia|N01036 830, Manila, Philippines|N01036 831, Manila, Philippines|N01036 829, Quezon, Philippines|N01036 804, Singapore, Singapore|N01036 806, Singapore, Singapore|N01036 807, Singapore, Singapore|N01036 828, Changhua, Taiwan|N01036 827, Hualien City, Taiwan|N01036 825, Kaohsiung City, Taiwan|N01036 834, Kaohsiung, Taiwan|N01036 835, Kaohsiung, Taiwan|N01036 823, Taichung city, Taiwan|N01036 817, Taichung, Taiwan|N01036 818, Tainan, Taiwan|N01036 819, Taipei, Taiwan|N01036 820, Taipei, Taiwan|N01036 821, Taipei, Taiwan|N01036 822, Taoyuan, Taiwan|N01036 809, Bangkok, Thailand|N01036 840, Bangkok, Thailand|N01036 841, Bangkok, Thailand|N01036 839, Chiang Mai, Thailand|N01036 810, Khon Kaen, Thailand Less <<
NCT00849485 Healthy Phase 1 Completed - Canada, Quebec ... More >> SFBC Anapharm Sainte-Foy, Quebec, Canada, G1V 2K8 Less <<
NCT00859430 - Completed - -
NCT00324454 Motor Neuron Disease ... More >> Amyotrophic Lateral Sclerosis Primary Lateral Sclerosis Progressive Muscular Atrophy Less << Phase 2 Completed - United States, North Carolina ... More >> Duke University ALS Clinic - 932 Morreene Road Durham, North Carolina, United States, 27705 Less <<
NCT00280696 Epilepsies, Partial Phase 3 Completed - Japan ... More >> Aichi-gun, Aichi, Japan Nagoya, Aichi, Japan Nayoga, Aichi, Japan Hirosaki, Aomori, Japan Kitakyusyu, Fukuoka, Japan Kurume, Fukuoka, Japan Fukuyama, Hiroshima, Japan Asahikawa, Hokkaido, Japan Hakodate, Hokkaido, Japan Sapporo, Hokkaido, Japan Kobe, Hyogo, Japan Kahoku-gun, Ishikawa, Japan Kikuchi-gun, Kumamoto, Japan Sendai, Miyagi, Japan Omura, Nagasaki, Japan Izumi, Osaka, Japan Neyagawa, Osaka, Japan Suita, Osaka, Japan Kawachi-gun, Tochigi, Japan Kodaira, Tokyo, Japan Ube, Yamaguchi, Japan Chiba, Japan Fukuoka, Japan Gihu, Japan Hiroshima, Japan Kagoshima, Japan Kobe, Japan Kyoto, Japan Miyazaki, Japan Nagaoka, Japan Niigata, Japan Okayama, Japan Osaka, Japan Shizuoka, Japan Tokyo, Japan Toyama, Japan Yamagata, Japan Less <<
NCT00175890 Epilepsy, Partial Phase 3 Completed - -
NCT00859521 Healthy Phase 1 Completed - United States, Texas ... More >> CEDRA Clinical Research, LLC San Antonio, Texas, United States, 78217 Less <<
NCT01491113 Healthy Subjects ... More >> Renal Impairments Less << Phase 4 Completed - Japan ... More >> 1 Fukuoka, Japan 2 Ibaraki, Japan Less <<
NCT00859521 - Completed - -
NCT00566046 Epilepsy, Post-Traumatic Phase 3 Terminated(Sponsor decision be... More >>cause of to small enrollment) Less << - France ... More >> Neurologie - CHU Angers Angers, France Neurology - CHU Bordeaux Bordeaux, France Neurologie - CHU Caen Caen, France Neurochirurgie-CHU Grenoble Grenoble, France Neurology - CHU Rennes Grenoble, France Neurophysiologie Clinique - CHU Lille Lille, France Neurophysiologie clinique - CHU Lyon (Hôpital neurologique) Lyon, France Beurophysiologie clinique - CHU Marseille Marseille, France Epileptologie - CHU Montpellier Montpellier, France Neurologie - CHU Nancy Nancy, France Neurochirurgie-Paris Saint Anne Paris, France, 75674 Neurologie - CHU Rennes Rennes, France, 35000 Explorations Fonctionnelles Neurologiques - CHU Nantes Rennes, France Neurologie - CHU Rouen Rouen, France Neurologie - CHU Tours Hopital Trousseau Tours, France Less <<
NCT01491113 - Completed - -
NCT00325182 Alcoholism Phase 4 Completed - United States, Massachusetts ... More >> Boston University Dept of Psychiatry Clinical Studies Unit Boston, Massachusetts, United States, 02118 Less <<
NCT02098941 - Unknown December 2014 Korea, Republic of ... More >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Sang kun Lee, MD,PhD       sangkun2923@gmail.com    Contact: Jung-won Shin, MD       limitsum@gmail.com    Principal Investigator: Sang kun Lee, MD, PhD Less <<
NCT00262262 Postoperative Pain Not Applicable Completed - Denmark ... More >> Department of neurology, Odense Universityhospital Odense, Fyn, Denmark, 5000 Less <<
NCT02334722 Brain Neoplasms|Brain Cancer|B... More >>rain Tumors|Cancer of the Brain|Cancer of Brain|Seizure Less << PHASE4 COMPLETED 2020-10-07 University of Florida, Gainesv... More >>ille, Florida, 32610, United States Less <<
NCT00254657 Fibromyalgia Not Applicable Completed - United States, California ... More >> UCSF San Francisco, California, United States, 94115 Less <<
NCT00286260 Painful Polyneuropathy Phase 4 Completed - Denmark ... More >> Department of Neurology, Odense University Hospital Odense C, Denmark, DK-5000 Less <<
NCT00160628 Epilepsy, Partial PHASE3 COMPLETED 2025-10-04 -
NCT02866877 - Recruiting December 2018 United States, Colorado ... More >> University of Colorado Hospital Recruiting Aurora, Colorado, United States, 80045 Contact: Gerard Barber    720-848-6964    gerard.barber@uchealth.org Less <<
NCT00227461 Aphasia Strok... More >>e Less << Phase 1 Active, not recruiting December 2019 United States, New Jersey ... More >> Kessler Foundation West Orange, New Jersey, United States, 07052 Less <<
NCT00603135 Status Epilepticus, Non-Convul... More >>sive Less << Phase 2 Withdrawn March 2010 Switzerland ... More >> University Hospital Basel Basel, Switzerland, 4031 Less <<
NCT00423527 Multiple Sclerosis Phase 4 Completed - Denmark ... More >> Department of Neurology, Odense University Hospital Odense C, Denmark, DK-5000 Less <<
NCT00160511 Neuralgia, Postherpetic PHASE2 COMPLETED 2025-09-05 -
NCT00566150 Bipolar Depression Not Applicable Completed - United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06519 Less <<
NCT00545012 Absence Seizures PHASE2 COMPLETED 2025-05-03 -
NCT00370838 - Completed - -
NCT00544050 Epilepsy PHASE2 COMPLETED 2025-05-03 -
NCT00265109 Body Dysmorphic Disorder PHASE4 COMPLETED 2025-01-08 Rhode Island Hospital Body Dys... More >>morphic Disorder Program, Providence, Rhode Island, 02903, United States Less <<
NCT00566150 - Completed - -
NCT00265109 Body Dysmorphic Disorder PHASE4 COMPLETED 2025-01-08 Rhode Island Hospital Body Dys... More >>morphic Disorder Program, Providence, Rhode Island, 02903, United States Less <<
NCT00291655 Epilepsy PHASE3 COMPLETED 2025-04-08 Brugge, Belgium|Edegem, Belgiu... More >>m|Gent, Belgium|Haine St Paul, Belgium|Jette, Belgium|Kortrijk, Belgium|Leuven, Belgium|Oostende, Belgium|Sofia, Bulgaria|Varna, Bulgaria|Hus (helsinki), Finland|Kuopio, Finland|Tampere, Finland|Blaye, France|Bordeaux, France|Brest, France|Carcassonne, France|Cherbourg, France|Lille, France|Lyon Cedex, France|Nancy, France|Rennes, France|Saint Brieuc, France|Saint Quentin, France|TOULOUSE Cedex 04, France|Valenciennes, France|Czestochowa, Poland|Krakow, Poland|Olstyn, Poland|Poznan, Poland|Warszawa, Poland|Biel, Switzerland|Lausanne, Switzerland|St Gallen, Switzerland|Zurich, Switzerland Less <<
NCT02602860 Healthy Volunteers Phase 1 Completed - United States, Connecticut ... More >> Ep0074 001 New Haven, Connecticut, United States Less <<
NCT00961441 Epilepsy Phase 2 Completed - United States, Alabama ... More >> Mobile, Alabama, United States United States, Arizona Phoenix, Arizona, United States United States, Arkansas Little Rock, Arkansas, United States United States, Connecticut Fairfield, Connecticut, United States United States, Maryland Bethesda, Maryland, United States United States, Texas Dallas, Texas, United States Less <<
NCT00961441 - Completed - -
NCT01498822 Epilepsy Phase 4 Completed - Korea, Republic of ... More >> 05 Busan, Korea, Republic of 10 Busan, Korea, Republic of 16 Busan, Korea, Republic of 06 Daejeon, Korea, Republic of 18 Daejeon, Korea, Republic of 23 Gangwon-Do, Korea, Republic of 08 Goyang-si, Korea, Republic of 09 Goyang-si, Korea, Republic of 07 Gwangju, Korea, Republic of 22 Jung-Gu, Korea, Republic of 14 Seongnam-si, Korea, Republic of 01 Seoul, Korea, Republic of 02 Seoul, Korea, Republic of 03 Seoul, Korea, Republic of 04 Seoul, Korea, Republic of 11 Seoul, Korea, Republic of 12 Seoul, Korea, Republic of 13 Seoul, Korea, Republic of 15 Seoul, Korea, Republic of 17 Seoul, Korea, Republic of 20 Seoul, Korea, Republic of 21 Seoul, Korea, Republic of 19 Ulsan, Korea, Republic of Less <<
NCT00370838 Tic Disorders ... More >> Tourette Syndrome Less << Phase 4 Completed - United States, Maryland ... More >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Less <<
NCT01498822 - Completed - -
NCT02920060 Grand Mal Status Epilepticus Phase 2 Completed - -
NCT00291655 Epilepsy PHASE3 COMPLETED 2025-04-08 Brugge, Belgium|Edegem, Belgiu... More >>m|Gent, Belgium|Haine St Paul, Belgium|Jette, Belgium|Kortrijk, Belgium|Leuven, Belgium|Oostende, Belgium|Sofia, Bulgaria|Varna, Bulgaria|Hus (helsinki), Finland|Kuopio, Finland|Tampere, Finland|Blaye, France|Bordeaux, France|Brest, France|Carcassonne, France|Cherbourg, France|Lille, France|Lyon Cedex, France|Nancy, France|Rennes, France|Saint Brieuc, France|Saint Quentin, France|TOULOUSE Cedex 04, France|Valenciennes, France|Czestochowa, Poland|Krakow, Poland|Olstyn, Poland|Poznan, Poland|Warszawa, Poland|Biel, Switzerland|Lausanne, Switzerland|St Gallen, Switzerland|Zurich, Switzerland Less <<
NCT00152516 Epilepsy, Partial Phase 3 Completed - -
NCT02208492 Focal Epilepsy Phase 4 Completed - Korea, Republic of ... More >> Severance hospital Seoul, Korea, Republic of, 120-752 Less <<
NCT02201251 Epilepsy Phase 3 Recruiting November 30, 2021 -
NCT00150813 Epilepsy, Tonic-clonic PHASE3 COMPLETED 2007-05-29 Beroun, Czechia|Brno, Czechia|... More >>Ceske Budejovice, Czechia|Praha 1, Czechia|Praha 5, Czechia|Rychnov nad Kneznou, Czechia|Budapest, Hungary|Debrecen, Hungary|Pécs, Hungary|Szeged, Hungary|Bia?ystok, Poland|Gdańsk, Poland|Katowice, Poland|Lublin, Poland|Szczecin, Poland|Warszawa, Poland|?ód?, Poland|G?teborg, Sweden|Helsingborg, Sweden|Huddinge, Sweden|Karlstad, Sweden|Uppsala, Sweden Less <<
NCT00150748 Generalized Epilepsy Phase 3 Completed - -
NCT00571155 Primary Brain Tumor ... More >> Epilepsy Less << Phase 4 Completed - Germany ... More >> University Hospital Tuebingen, Department of General Neurology Tuebingen, Baden-Wuerttemberg, Germany, 72076 Less <<
NCT01239212 Seizures Phase 1 Phase 2 Completed - United States, Ohio ... More >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Less <<
NCT01239212 - Completed - -
NCT00152516 - Completed - -
NCT01063764 Epilepsy|Partial Seizures PHASE3 COMPLETED 2025-10-13 21, Chuo, Japan|12, Hakodate, ... More >>Japan|22, Hamamatsu, Japan|28, Hiroshima, Japan|7, Izumi, Japan|9, Kobe, Japan|3, Kodaira, Japan|30, Koga, Japan|10, Koushi, Japan|31, Kurume, Japan|23, Kyoto, Japan|2, Nagaoka, Japan|5, Nagoya, Japan|6, Nagoya, Japan|8, Neyagawa, Japan|1, Niigata, Japan|27, Okayama, Japan|24, Osaka, Japan|25, Osaka, Japan|11, Sapporo, Japan|13, Sendai, Japan|4, Shizuoka, Japan|26, Takatsuki, Japan|16, Tokyo, Japan|17, Tokyo, Japan|15, Yachiyo, Japan|14, Yamagata, Japan|19, Yokohama, Japan|20, Yokohama, Japan Less <<
NCT01063764 Epilepsy|Partial Seizures PHASE3 COMPLETED 2025-10-13 21, Chuo, Japan|12, Hakodate, ... More >>Japan|22, Hamamatsu, Japan|28, Hiroshima, Japan|7, Izumi, Japan|9, Kobe, Japan|3, Kodaira, Japan|30, Koga, Japan|10, Koushi, Japan|31, Kurume, Japan|23, Kyoto, Japan|2, Nagaoka, Japan|5, Nagoya, Japan|6, Nagoya, Japan|8, Neyagawa, Japan|1, Niigata, Japan|27, Okayama, Japan|24, Osaka, Japan|25, Osaka, Japan|11, Sapporo, Japan|13, Sendai, Japan|4, Shizuoka, Japan|26, Takatsuki, Japan|16, Tokyo, Japan|17, Tokyo, Japan|15, Yachiyo, Japan|14, Yamagata, Japan|19, Yokohama, Japan|20, Yokohama, Japan Less <<
NCT02199509 Oromandibular Dystonia|Cranial... More >> Dystonia Less << PHASE2 COMPLETED 2025-03-16 National Institutes of Health ... More >>Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, 20892, United States Less <<
NCT01660672 Seizure Epile... More >>psy Cerebral Malaria Less << Phase 1 Phase 2 Completed - Malawi ... More >> Queen Elizabeth Central Hospital Blantyre, Malawi, 3 Less <<
NCT00150813 Epilepsy, Tonic-clonic PHASE3 COMPLETED 2007-05-29 Beroun, Czechia|Brno, Czechia|... More >>Ceske Budejovice, Czechia|Praha 1, Czechia|Praha 5, Czechia|Rychnov nad Kneznou, Czechia|Budapest, Hungary|Debrecen, Hungary|Pécs, Hungary|Szeged, Hungary|Bia?ystok, Poland|Gdańsk, Poland|Katowice, Poland|Lublin, Poland|Szczecin, Poland|Warszawa, Poland|?ód?, Poland|G?teborg, Sweden|Helsingborg, Sweden|Huddinge, Sweden|Karlstad, Sweden|Uppsala, Sweden Less <<
NCT01261416 - Completed - United States, Ohio ... More >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Less <<
NCT01660672 - Completed - -
NCT00141115 Alcoholism Ge... More >>neralized Anxiety Disorder Panic Disorder Social Phobia Anxiety Disorders Less << Phase 2 Completed - United States, New York ... More >> New York State Psychiatric Institute New York, New York, United States, 10032 Less <<
NCT01618903 Human Volunteers Phase 1 Completed - China ... More >> 1 Shanghai, China Less <<
NCT00141115 - Completed - -
NCT01725009 Healthy Volunteers Phase 1 Completed - Japan ... More >> 01 Tokyo, Japan Less <<
NCT02199509 Oromandibular Dystonia|Cranial... More >> Dystonia Less << PHASE2 COMPLETED 2025-03-16 National Institutes of Health ... More >>Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, 20892, United States Less <<
NCT00926302 Healthy Not Applicable Completed - -
NCT01228747 - Completed - -
NCT00577005 Cocaine Dependence ... More >> Opioid Dependency Less << Phase 2 Completed - United States, Connecticut ... More >> VA CT Healthcare System West Haven, Connecticut, United States, 06516 Less <<
NCT00577005 - Completed - -
NCT01475656 - Terminated(difficulty with rec... More >>ruitment) Less << - United States, Ohio ... More >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45215 Less <<
NCT01228747 Epilepsy Gene... More >>ralized Tonic-Clonic Seizures Less << Phase 3 Completed - -
NCT01398956 Epilepsy|Generalized Tonic-clo... More >>nic Seizures Less << PHASE3 COMPLETED 2025-04-16 152, Fujisawa, Japan|112, Fuku... More >>oka, Japan|113, Fukuoka, Japan|165, Fukuoka, Japan|166, Fukuoka, Japan|187, Fukushima, Japan|107, Gifu, Japan|162, Himeji, Japan|110, Hiroshima, Japan|117, Hokkaido, Japan|130, Hokkaido, Japan|176, Hokkaido, Japan|143, Kagoshima, Japan|156, Kagoshima, Japan|120, Kodaira, Japan|105, Kokubunji, Japan|306, Koshi, Japan|172, Miyazaki, Japan|179, Miyazaki, Japan|305, Nagoya, Japan|106, Niigata, Japan|153, Niigata, Japan|109, Okayama, Japan|174, Osaka, Japan|119, Saitama, Japan|147, Sakai, Japan|194, Sakai, Japan|304, Sapporo, Japan|138, Tochigi, Japan|184, Tokyo, Japan|190, Tokyo, Japan|111, Ube, Japan Less <<
NCT01398956 Epilepsy|Generalized Tonic-clo... More >>nic Seizures Less << PHASE3 COMPLETED 2025-04-16 152, Fujisawa, Japan|112, Fuku... More >>oka, Japan|113, Fukuoka, Japan|165, Fukuoka, Japan|166, Fukuoka, Japan|187, Fukushima, Japan|107, Gifu, Japan|162, Himeji, Japan|110, Hiroshima, Japan|117, Hokkaido, Japan|130, Hokkaido, Japan|176, Hokkaido, Japan|143, Kagoshima, Japan|156, Kagoshima, Japan|120, Kodaira, Japan|105, Kokubunji, Japan|306, Koshi, Japan|172, Miyazaki, Japan|179, Miyazaki, Japan|305, Nagoya, Japan|106, Niigata, Japan|153, Niigata, Japan|109, Okayama, Japan|174, Osaka, Japan|119, Saitama, Japan|147, Sakai, Japan|194, Sakai, Japan|304, Sapporo, Japan|138, Tochigi, Japan|184, Tokyo, Japan|190, Tokyo, Japan|111, Ube, Japan Less <<
NCT01292837 Epilepsy|Generalized Tonic-clo... More >>nic Seizures Less << PHASE3 COMPLETED 2025-06-13 191, Akita, Japan|184, Bunkyo,... More >> Japan|309, Bunkyo, Japan|107, Gifu, Japan|303, Hiroshima, Japan|108, Kobe, Japan|302, Kodaira, Japan|306, Koshi, Japan|136, Moriyama, Japan|305, Nagoya, Japan|190, Nerima, Japan|125, Neyagawa, Japan|301, Niigata, Japan|116, Ohmura, Japan|109, Okayama, Japan|308, Onojo, Japan|119, Saitama, Japan|117, Sapporo, Japan|304, Sapporo, Japan|103, Sendai, Japan|138, Shimotsuke, Japan|307, Shizuoka, Japan|139, Takatsuki, Japan|135, Tsu, Japan|193, Yokohama, Japan|310, Yufu, Japan Less <<
NCT01292837 Epilepsy|Generalized Tonic-clo... More >>nic Seizures Less << PHASE3 COMPLETED 2025-06-13 191, Akita, Japan|184, Bunkyo,... More >> Japan|309, Bunkyo, Japan|107, Gifu, Japan|303, Hiroshima, Japan|108, Kobe, Japan|302, Kodaira, Japan|306, Koshi, Japan|136, Moriyama, Japan|305, Nagoya, Japan|190, Nerima, Japan|125, Neyagawa, Japan|301, Niigata, Japan|116, Ohmura, Japan|109, Okayama, Japan|308, Onojo, Japan|119, Saitama, Japan|117, Sapporo, Japan|304, Sapporo, Japan|103, Sendai, Japan|138, Shimotsuke, Japan|307, Shizuoka, Japan|139, Takatsuki, Japan|135, Tsu, Japan|193, Yokohama, Japan|310, Yufu, Japan Less <<
NCT00985348 Healthy Phase 1 Completed - United Kingdom ... More >> London, United Kingdom Less <<
NCT00367432 Epilepsies|Partial PHASE3 COMPLETED 2025-12-10 Aichi-gun, Aichi, Japan|Nagoya... More >>, Aichi, Japan|Hirosaki, Aomori, Japan|Matsudo, Chiba, Japan|Kitakyusyu, Fukuoka, Japan|Koga, Fukuoka, Japan|Kurume, Fukuoka, Japan|Fukuyama, Hiroshima, Japan|Asahikawa, Hokkaido, Japan|Hakodate, Hokkaido, Japan|Sapporo, Hokkaido, Japan|Kobe, Hyogo, Japan|Kahoku-gun, Ishikawa, Japan|Kanazawa, Ishikawa, Japan|Zentsuji, Kagawa, Japan|Koshi, Kumamoto, Japan|Tsu, Mie, Japan|Iwanuma, Miyagi, Japan|Sendai, Miyagi, Japan|Omura, Nagasaki, Japan|Kashihara, Nara, Japan|Nagaoka, Niigata, Japan|Beppu, Oita, Japan|Izumi, Osaka, Japan|Neyagawa, Osaka, Japan|Suita, Osaka, Japan|Takatsuki, Osaka, Japan|Iruma-gun, Saitama, Japan|Shimotsuga-gun, Tochigi, Japan|Shimotsuke, Tochigi, Japan|Komatsushima, Tokushima, Japan|Chiyoda-Ku, Tokyo, Japan|Kodaira, Tokyo, Japan|Kokubunji, Tokyo, Japan|Shinjuku-ku, Tokyo, Japan|Taito-ku, Tokyo, Japan|Ube, Yamaguchi, Japan|Aomori, Japan|Chiba, Japan|Fukuoka, Japan|Fukushima, Japan|Gifu, Japan|Hiroshima, Japan|Kagoshima, Japan|Kumamoto, Japan|Kyoto, Japan|Miyazaki, Japan|Niigata, Japan|Okayama, Japan|Osaka, Japan|Shizuoka, Japan|Toyama, Japan|Yamagata, Japan Less <<
NCT00505934 Epilepsy PHASE2 COMPLETED 2025-03-10 San Diego, California, United ... More >>States|Buffalo, New York, United States|Philadelphia, Pennsylvania, United States|Nashville, Tennessee, United States|Fort Worth, Texas, United States|Richmond, Virginia, United States|Gent, Belgium|Leuven, Belgium|Amiens, France|Lille, France|Paris, France|Vandoeuvre Les Nancy, France|Heidelberg, Germany|Kehl, Germany|Kiel, Germany|Torreon, Coahuila, Mexico|Puebla, CP, Mexico|Aguascalientes, Mexico|Guadalajara, Mexico|Mexico City, Mexico|Puebla, Mexico|Ankara, Turkey|Izmir, Turkey Less <<
NCT01394224 Healthy Volunteers Phase 1 Completed - United Kingdom ... More >> London, United Kingdom Less <<
NCT00419393 Epilepsy Phase 3 Completed - -
NCT00505934 Epilepsy PHASE2 COMPLETED 2025-03-10 San Diego, California, United ... More >>States|Buffalo, New York, United States|Philadelphia, Pennsylvania, United States|Nashville, Tennessee, United States|Fort Worth, Texas, United States|Richmond, Virginia, United States|Gent, Belgium|Leuven, Belgium|Amiens, France|Lille, France|Paris, France|Vandoeuvre Les Nancy, France|Heidelberg, Germany|Kehl, Germany|Kiel, Germany|Torreon, Coahuila, Mexico|Puebla, CP, Mexico|Aguascalientes, Mexico|Guadalajara, Mexico|Mexico City, Mexico|Puebla, Mexico|Ankara, Turkey|Izmir, Turkey Less <<
NCT00419393 - Completed - -
NCT00535392 Epilepsy PHASE2 COMPLETED 2025-02-10 La Jolla, California, United S... More >>tates|Boston, Massachusetts, United States|Chesterfield, Missouri, United States|Buffalo, New York, United States|Philadelphia, Pennsylvania, United States|Nashville, Tennessee, United States|Fort Worth, Texas, United States|Richmond, Virginia, United States|Milwaukee, Wisconsin, United States|Brussels, Belgium|Gent, Belgium|Leuven, Belgium|Amiens, France|Lille, France|Paris, France|Heidelberg, Germany|Kehl, Germany|Torreon, Coahuila, Mexico|Puebla, CP, Mexico|Aguascalientes, Mexico|Guadalajara, Mexico|Mexico City, Mexico|Puebla, Mexico|Ankara, Turkey|Izmir, Turkey Less <<
NCT01137110 Subarachnoid Hemorrhage Phase 3 Completed - United States, Missouri ... More >> Barnes-jewish Hospital Saint Louis, Missouri, United States, 63110 Less <<
NCT00760318 Cervical Dystonia Phase 2 Terminated(Sponsor decided to ... More >>stop enrollment to review data.) Less << - -
NCT01168687 Alcohol Abuse ... More >> Drug Abuse Less << Not Applicable Completed - United States, California ... More >> Children's Hospital Oakland Research Institute- CRC Berkeley, California, United States, 94705 Less <<
NCT00535392 Epilepsy PHASE2 COMPLETED 2025-02-10 La Jolla, California, United S... More >>tates|Boston, Massachusetts, United States|Chesterfield, Missouri, United States|Buffalo, New York, United States|Philadelphia, Pennsylvania, United States|Nashville, Tennessee, United States|Fort Worth, Texas, United States|Richmond, Virginia, United States|Milwaukee, Wisconsin, United States|Brussels, Belgium|Gent, Belgium|Leuven, Belgium|Amiens, France|Lille, France|Paris, France|Heidelberg, Germany|Kehl, Germany|Torreon, Coahuila, Mexico|Puebla, CP, Mexico|Aguascalientes, Mexico|Guadalajara, Mexico|Mexico City, Mexico|Puebla, Mexico|Ankara, Turkey|Izmir, Turkey Less <<
NCT01168687 - Completed - -
NCT00618436 - Completed - -
NCT01618877 Human Volunteers Phase 1 Completed - China ... More >> 1 Shanghai, China Less <<
NCT02647437 Schizophrenia Not Applicable Recruiting December 2019 United States, Colorado ... More >> University of Colorado Anschutz Medical Campus Recruiting Aurora, Colorado, United States, 80045 Contact: Kristina T Legget, Ph.D.    303-724-5809    kristina.legget@ucdenver.edu Less <<
NCT00367432 Epilepsies|Partial PHASE3 COMPLETED 2025-12-10 Aichi-gun, Aichi, Japan|Nagoya... More >>, Aichi, Japan|Hirosaki, Aomori, Japan|Matsudo, Chiba, Japan|Kitakyusyu, Fukuoka, Japan|Koga, Fukuoka, Japan|Kurume, Fukuoka, Japan|Fukuyama, Hiroshima, Japan|Asahikawa, Hokkaido, Japan|Hakodate, Hokkaido, Japan|Sapporo, Hokkaido, Japan|Kobe, Hyogo, Japan|Kahoku-gun, Ishikawa, Japan|Kanazawa, Ishikawa, Japan|Zentsuji, Kagawa, Japan|Koshi, Kumamoto, Japan|Tsu, Mie, Japan|Iwanuma, Miyagi, Japan|Sendai, Miyagi, Japan|Omura, Nagasaki, Japan|Kashihara, Nara, Japan|Nagaoka, Niigata, Japan|Beppu, Oita, Japan|Izumi, Osaka, Japan|Neyagawa, Osaka, Japan|Suita, Osaka, Japan|Takatsuki, Osaka, Japan|Iruma-gun, Saitama, Japan|Shimotsuga-gun, Tochigi, Japan|Shimotsuke, Tochigi, Japan|Komatsushima, Tokushima, Japan|Chiyoda-Ku, Tokyo, Japan|Kodaira, Tokyo, Japan|Kokubunji, Tokyo, Japan|Shinjuku-ku, Tokyo, Japan|Taito-ku, Tokyo, Japan|Ube, Yamaguchi, Japan|Aomori, Japan|Chiba, Japan|Fukuoka, Japan|Fukushima, Japan|Gifu, Japan|Hiroshima, Japan|Kagoshima, Japan|Kumamoto, Japan|Kyoto, Japan|Miyazaki, Japan|Niigata, Japan|Okayama, Japan|Osaka, Japan|Shizuoka, Japan|Toyama, Japan|Yamagata, Japan Less <<
NCT02229123 Neonatal Seizures Phase 2 Recruiting March 1, 2020 France ... More >> Service de réanimation néonatale Recruiting Angers, France, 49000 Contact: Stephane Le Bouedec, Dr       StLeBouedec@chu-angers.fr    Contact: Geraldine Gascoin, Pr       GeGascoin@chu-angers.fr    Service de réanimation néonatale Recruiting Lille, France, 59037 Contact: Florence Flamein, Dr       Florence.flamein@chru-lille.fr    Contact: Laurent Storme, Pr       laurent.storme@chru-lille.fr    Principal Investigator: Florence Flamein, Dr          Service de réanimation et service néonatale Not yet recruiting Orleans, France, 45100 Contact: Bérengère KIRECHE, PH       berengere.kireche@chr-orleans.fr    Contact: Evelyne WERNER, PH       evelyne.werner@chr-orleans.fr    Service de réanimation néonatale et pédiatrique Not yet recruiting Paris, France, 75012 Contact: Isabelle GUELLEC, PH       isabelle.guellec@aphp.fr    Contact: Pierre_Louis LEGER, PH       pierre-louis.leger@aphp.fr    Service de réanimation néonatale Not yet recruiting Reims, France, 51092 Contact: Nathalie BEDNAREK, PU-PH       nbednarek@chu-reims.fr    Néonatologie Recruiting Rennes, France, 35000 Contact: Patrick Pladys, Pr       patrick.pladys@chu-rennes.fr    Contact: Alain Beuchee, Pr       alain.beuchee@chu-rennes.fr    Principal Investigator: Patrick Pladys, Pr          Service de Pédiatrie néonatale et réanimation Recruiting Rouen, France, 76031 Contact: Alexandra Chadie, Dr       alexandra.chadie@chu-rouen.fr    Contact: Stephane Marret, Pr       stephane.marret@chu-rouen.fr    Principal Investigator: Alexandra Chadie, Dr          Service de Néonatologie Recruiting Tours, France, 37 000 Contact: Geraldine Favrais, Dr    0247474749    g.favrais@chu-tours.fr    Contact: Estelle Boivin    0247474620    e.boivin@chu-tours.fr    Principal Investigator: Geraldine Favrais, Dr Less <<
NCT00518570 Premenstrual Dysphoric Disorde... More >>r Less << COMPLETED 2025-10-06 Berkshire Medical Center, Clin... More >>ical Trials Program, Department of Psychiatry, Pittsfield, Massachusetts, 01201, United States Less <<
NCT01935908 Subarachnoid Hemorrhage ... More >> Seizures Less << Phase 4 Withdrawn(no funding) - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less <<
NCT00618436 Traumatic Brain Injury ... More >> Subarachnoid Hemorrhage Less << Phase 4 Completed - United States, Ohio ... More >> University of Cincinnati Hospital Cincinnati, Ohio, United States, 45220 Less <<
NCT00461409 Seizures Term... More >> Neonates Less << Phase 1 Phase 2 Completed - United States, California ... More >> UCSD Hillcrest Medical Center San Diego, California, United States, 92103 Sharpe Mary Birch Hospital San Diego, California, United States, 92123 New Zealand Auckland City Hospital Auckland, New Zealand Less <<
NCT00884052 Seizures Diso... More >>rder of Fetus or Newborn Less << Phase 1 Phase 2 Completed - United States, California ... More >> University of California, San Diego Medical Center / Neonatal Intensive Care Unit (NICU) San Diego, California, United States, 92103 Less <<
NCT01132352 Healthy PHASE1 COMPLETED 2025-11-03 MDS Pharma Services, Neptune, ... More >>New Jersey, 07753, United States Less <<
NCT00758277 Alcohol Dependence ... More >> Alcoholic Relapse Less << Phase 3 Completed - Germany ... More >> Klinikum Nürnberg Nord Nürnberg, Bayern, Germany, 90419 Westfälisches Zentrum Bochum, Psychiatrie, Psychotherapie & Psychosomatik, Klinik der Ruhr-Universität Bochum, NRW, Germany, 44791 Klinik und Poliklinik für Psychiatrie und Psychotherapie Bonn, NRW, Germany, 53105 Klinik für Psychiatrie, Psychotherapie und Suchtmedizin Kliniken Essen - Mitte Essen, NRW, Germany, 45136 Klinik für abhängiges Verhalten und Suchtmedizin, Rheinische Kliniken Essen, Kliniken der Universität Duisburg-Essen Essen, NRW, Germany, 45147 Klinik für abhängiges Verhalten und Suchtmedizin, Rheinische Kliniken, Essen, Kliniken der Universität Duisburg - Essen Essen, NRW, Germany, 45147 Klinik für Psychiatrie und Psychotherapie der Martin-Luther-Universität Halle Halle, Sachsen-Anhalt, Germany, 06097 Charité Campus Mitte, Klinik für Psychiatrie und Psychotherapie Berlin, Germany, 10117 PUK Charité im SHK Berlin, Germany, 10559 Vivantes, Wenckebach-Krankenhaus, Klinik für Psychiatrie und Psychotherapie, Gerontopsychiatrie/Psychosomatik Berlin, Germany, 12099 Klinik für Psychiatrie und Psychotherapie, Jüdisches Krankenhaus Berlin Berlin, Germany, 13347 Less <<
NCT01131897 Healthy PHASE1 COMPLETED 2025-11-03 MDS Pharma Services, Neptune, ... More >>New Jersey, 07753, United States Less <<
NCT01229735 Epilepsy Phase 4 Completed - Korea, Republic of ... More >> 14 Busan, Korea, Republic of 21 Busan, Korea, Republic of 8 Busan, Korea, Republic of 9 Busan, Korea, Republic of 12 Daegu, Korea, Republic of 13 Daegu, Korea, Republic of 10 Daejeon, Korea, Republic of 25 Daejeon, Korea, Republic of 15 Gwangju, Korea, Republic of 7 Incheon, Korea, Republic of 11 Kyunggi-Do, Korea, Republic of 19 Kyunggi-do, Korea, Republic of 23 Kyunggi-Do, Korea, Republic of 24 Kyunggi-Do, Korea, Republic of 16 Seoul, Korea, Republic of 17 Seoul, Korea, Republic of 18 Seoul, Korea, Republic of 1 Seoul, Korea, Republic of 2 Seoul, Korea, Republic of 3 Seoul, Korea, Republic of 4 Seoul, Korea, Republic of 5 Seoul, Korea, Republic of 6 Seoul, Korea, Republic of 22 Ulsan, Korea, Republic of Less <<
NCT02002819 Alzheimer's Disease Phase 2 Recruiting December 2019 United States, California ... More >> UCSF Active, not recruiting San Francisco, California, United States, 94158 United States, Minnesota University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Kasey Ah Pook, BS    612-625-6631    ahpoo001@umn.edu    Principal Investigator: Keith A Vossel, MD, MSc Less <<
NCT01506882 Epilepsy Part... More >>ial Onset Seizures Less << Phase 3 Completed - Japan ... More >> 19 Aomori, Japan 33 Asaka, Japan 21 Daito, Japan 12 Fujisawa, Japan 14 Hamamatsu, Japan 11 Himeji, Japan 30 Hirosaki, Japan 8 Kagoshima, Japan 20 Kamakura, Japan 17 Kawasaki, Japan 3 Kitakyusyu, Japan 26 Kodaira, Japan 9 Kokubunji, Japan 32 Kyoto, Japan 25 Miyakonojo, Japan 5 Nagoya Aichi, Japan 4 Nara, Japan 22 Okayama, Japan 24 Osakasayama, Japan 15 Osaka, Japan 27 Osaka, Japan 13 Saitama, Japan 1 Sakai, Japan 29 Sapporo, Japan 2 Toyonaka, Japan 7 Ube, Japan 18 Yamagata, Japan Less <<
NCT01229735 - Completed - -
NCT01463033 Epilepsy|Post-traumatic Epilep... More >>sy Less << PHASE2 COMPLETED 2025-02-10 Children's National Medical Ce... More >>nter, Washington, District of Columbia, 20010, United States|MedStar Research Institute, Washington, District of Columbia, 20010, United States Less <<
NCT01506882 - Completed - -
NCT01318408 Epilepsy PHASE4 COMPLETED 2025-03-08 Drexel University College of M... More >>edicine, Dept of Neurology, Philadelphia, Pennsylvania, 19102, United States Less <<
NCT00593125 Cocaine Dependence ... More >> Opioid Dependence Less << Phase 2 Completed - United States, Connecticut ... More >> VA CT Healthcare System West Haven, Connecticut, United States, 06516 Less <<
NCT01318408 Epilepsy PHASE4 COMPLETED 2025-03-08 Drexel University College of M... More >>edicine, Dept of Neurology, Philadelphia, Pennsylvania, 19102, United States Less <<
NCT01463033 Epilepsy|Post-traumatic Epilep... More >>sy Less << PHASE2 COMPLETED 2025-02-10 Children's National Medical Ce... More >>nter, Washington, District of Columbia, 20010, United States|MedStar Research Institute, Washington, District of Columbia, 20010, United States Less <<
NCT02550028 Neonatal Seizures Phase 4 Recruiting December 2020 China, Shanghai ... More >> Children Hospital of Fudan University Recruiting Shanghai, Shanghai, China, 201102 Contact: Wenhao Zhou, Doctor    (+86)021-64931003    zwhchfu@126.com Less <<
NCT01407523 Epilepsy|Partial Onset Seizure... More >>s Less << PHASE2 COMPLETED 2025-02-12 1, Niigata-city, Niigata, Japa... More >>n|2, Shizuoka-city, Shizuoka, Japan|3, Kodaira-city, Tokyo, Japan|4, Yamagata-city, Yamagata, Japan Less <<
NCT03129360 Psychosis Sch... More >>izophrenia Schizo Affective Disorder Schizophreniform Less << Phase 2 Recruiting February 28, 2019 United States, New York ... More >> New York University School of Medicine Recruiting New York, New York, United States, 10016 Contact: Michelle Worthington, MA    646-754-4803    michelle.worthington@nyumc.org    Contact: Mariel Alano, MA    646 754 5466    mariel.alano@nyumc.org    Principal Investigator: Donald Goff, MD Less <<
NCT01407523 Epilepsy|Partial Onset Seizure... More >>s Less << PHASE2 COMPLETED 2025-02-12 1, Niigata-city, Niigata, Japa... More >>n|2, Shizuoka-city, Shizuoka, Japan|3, Kodaira-city, Tokyo, Japan|4, Yamagata-city, Yamagata, Japan Less <<
NCT02815410 Glioblastoma Multiforme Phase 2 Not yet recruiting June 2022 -
NCT03489044 Alzheimer Disease ... More >> Epilepsy Less << Phase 2 Enrolling by invitation January 2020 United Kingdom ... More >> Nuffield Department of Clinical Neuroscience Oxford, Oxfordshire, United Kingdom, OX39DU Less <<
NCT03340064 Partial Seizures PHASE3 COMPLETED 2023-07-28 Ep0100 15, Fukuoka, Japan|EP01... More >>00 3, Hamamatsu, Japan|EP0100 6, Izumi, Japan|Ep0100 20, Kobe, Japan|EP0100 2, Kodaira, Japan|Ep0100 21, Kofu, Japan|EP0100 7, Koshi, Japan|EP0100 9, Nagakute, Japan|EP0100 5, Niigata, Japan|Ep0100 12, OBU, Japan|Ep0100 14, Okayama, Japan|Ep0100 11, Omura, Japan|Ep0100 13, Osaka, Japan|Ep0100 18, Saitama, Japan|EP0100 4, Sapporo, Japan|Ep0100 10, Sendai, Japan|Ep0100 19, Sendai, Japan|Ep0100 16, Shinjuku-ku, Japan|Ep0100 17, Shinjuku-ku, Japan|EP0100 1, Shizuoka, Japan|Ep0100 22, Toyoake, Japan Less <<
NCT03107507 Neonatal Seizures Phase 4 Recruiting December 30, 2017 Egypt ... More >> Cairo University Children's Hospital (Abulreesh) Recruiting Cairo Governorate, Egypt Contact: Yara Shaheen Less <<
NCT01720667 Neonatal Seizures Phase 1 Phase 2 Active, not recruiting December 31, 2018 United States, California ... More >> University of California, San Diego Medical Center / Neonatal Intensive Care Unit (NICU) San Diego, California, United States, 92103 Less <<
NCT02607891 Epilepsy Phase 2 Recruiting August 2018 France ... More >> Not yet recruiting Elancourt, France Not yet recruiting Paris, France Not yet recruiting Rennes, France Netherlands Not yet recruiting Zwolle, Netherlands Poland Not yet recruiting Kraków, Poland Romania Not yet recruiting Bucuresti, Romania Spain Recruiting Barcelona, Spain Recruiting Madrid, Spain Recruiting Sevilla, Spain Sweden Recruiting Goteborg, Sweden Less <<
NCT02551003 Hypoxic Ischemic Encephalopath... More >>y Cerebral Infarction Less << Phase 1 Phase 2 Recruiting December 30, 2018 China, Shanghai ... More >> Children Hospital of Fudan University Recruiting Shanghai, Shanghai, China, 201102 Contact: Wenhao Zhou, Doctor    (+86)021-64931003    zwhchfu@126.com Less <<
NCT02451618 - Terminated(Trial was discontin... More >>ued due to inadequate signal from study eeg leads.) Less << - United States, California ... More >> Sharp Mary Birch Hospital for Women and Newborns San Diego, California, United States, 92123 Less <<
NCT01505569 Ewing's Family Tumors ... More >> Renal Tumors Hepatoblastoma Rhabdomyosarcoma Soft Tissue Sarcoma Primary Malignant Brain Neoplasms Retinoblastoma Medulloblastoma Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET) Atypical Teratoid/Rhabdoid Tumor (AT/RT) CNS Tumors Germ Cell Tumors Less << Not Applicable Recruiting January 2021 United States, Minnesota ... More >> Masonic Cancer Center, University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Kim Nelson    612-273-2925    knelso62@fairview.org    Principal Investigator: Heather Stefanski, MD, PhD Less <<
NCT02205931 Epilepsy Phase 4 Recruiting June 2019 United Kingdom ... More >> Birmingham Children's Hospital Recruiting Birmingham, United Kingdom, B4 6NH Contact: Shakti Agrawal, MBBS    0044 1213338149    shakti.agrawal@bch.nhs.uk    Principal Investigator: Shakti Agrawal, MBBS          Bristol Royal Hospital for Children Recruiting Bristol, United Kingdom, BS2 8AE Contact: Andrew Mallick, FRCPCH          Principal Investigator: Andrew Mallick          Addenbrooke's Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Contact: Alasdair Parker, MA    0044 1223 245151    alasdair.parker@addenbrookes.nhs.uk    Principal Investigator: Alasdair Parker, MA          Lancashire Teaching Hospitals NHS Foundation Trust Recruiting Lancashire, United Kingdom Contact: Helen Basu       Helen.Basu@lthtr.nhs.uk    Principal Investigator: Helen Basu          Leeds Teaching Hospital Recruiting Leeds, United Kingdom, LS1 3EX Contact: Helen McCullagh, RCPCH    0044 113 243 2799    h.mccullagh@nhs.net    Principal Investigator: Helen McCullagh, RCPCH          Alder Hey Children's Hospital Recruiting Liverpool, United Kingdom, L12 2AP Contact: Rachel Kneen, BMBS    0044 151 2525163    rachel.kneen@liverpool.ac.uk    Principal Investigator: Rachel Kneen, BMBS          Great Ormond Street Hospital Recruiting London, United Kingdom, WC1N 3JH Contact: Christin Eltze, MD Res    0044 207 405 9200 ext 5438    christin.eltze@gosh.nhs.uk    Principal Investigator: Christin Eltze, MD Res          St George's University Hospitals NHS Foundation Trust Recruiting London, United Kingdom Contact: Penny Fallon       Penny.Fallon@stgeorges.nhs.uk    Principal Investigator: Penny Fallon          Royal Manchester Children's Hospital Recruiting Manchester, United Kingdom, M13 0JE Contact: Tim Martland, RCPCH    0044 161 276 1234    timothy.martland@cmft.nhs.uk    Principal Investigator: Tim Martland, RCPCH          The Newcastle Upon Tyne Hospitals NHS Foundation Trust Recruiting Newcastle upon Tyne, United Kingdom Contact: Anita Devlin       Anita.Devlin@nuth.nhs.uk    Principal Investigator: Anita Devlin          Sheffield Children's NHS Foundation Trust Recruiting Sheffield, United Kingdom Contact: Archana Desurkar       Archana.Desurkar@sch.nhs.uk    Principal Investigator: Archana Desurkar Less <<
NCT02707965 Epilepsy Phase 4 Completed - United States, Maryland ... More >> University of Maryland, Baltimore Baltimore, Maryland, United States, 21201 Less <<
NCT02727101 Epilepsy Phase 4 Terminated(slow enrollment) - United States, Maryland ... More >> MidAtlantic Epilepsy and Sleep Center Bethesda, Maryland, United States, 20817 Less <<
NCT00552526 Epilepsy Ment... More >>al Retardation Less << Phase 4 Unknown December 2013 Norway ... More >> SSE, Nevrological dep. , Rikshospitalet University hospital Oslo, Norway Less <<
NCT02374567 Dementia Depr... More >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Less << Phase 3 Terminated - Germany ... More >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Less <<
NCT02472392 EWINGS SARCOMA Phase 1 Completed - United States, Kentucky ... More >> University of Louisville Louisville, Kentucky, United States, 40202 Less <<
NCT00068770 Brain and Central Nervous Syst... More >>em Tumors Less << Phase 2 Terminated(EORTC trail showed ... More >>TMZ & RT conferred significant survivial in this population) Less << - United States, Florida ... More >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114-2617 United States, North Carolina Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina, United States, 27157-1030 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Less <<
NCT00404248 - Completed - -
NCT01464359 Acute Myelogenous Leukemia ... More >> Refractory Acute Myelogenous Leukemia Less << Phase 2 Terminated(Slow accrual) - United States, Minnesota ... More >> Masonic Cancer Center, University of Minnesota Minneapolis, Minnesota, United States, 55455 Less <<
NCT01464359 - Terminated(Slow accrual) - -
NCT02670161 Brain Tumors ... More >>Epilepsy Migraine Mild Cognitive Impairment Concussion Multiple Sclerosis Neuropathy Parkinson's Restless Legs Syndrome Stroke Less << Phase 4 Enrolling by invitation April 2020 -
NCT00085683 - Completed - United States, Maryland ... More >> National Institute of Neurological Disorders and Stroke (NINDS) Bethesda, Maryland, United States, 20892 Less <<
NCT00404248 Brain and Central Nervous Syst... More >>em Tumors Less << Phase 1 Phase 2 Completed - United States, Alabama ... More >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3410 United States, Florida H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Josephine Ford Cancer Center at Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Less <<
NCT03636958 Refractory Epilepsy Not Applicable Not yet recruiting December 2022 France ... More >> Assistance Publique Des Hopitaux de Marseille Not yet recruiting Marseille, Paca, France, 13354 Contact: STANISLAS LAGARDE, MD    +33 491385554    Stanislas.LAGARDE@ap-hm.fr Less <<
NCT03490487 Benign Childhood Epilepsy With... More >> Centrotemporal Spikes Less << Phase 4 Not yet recruiting January 15, 2020 -
NCT02960607 Carcinoma, Non-Small-Cell Lung Phase 2 Unknown - China ... More >> Chinese Academy of Medical Sciences Recruiting Beijing, China Contact: Yutao Liu, MD       13911901165@139.com Less <<
NCT00068770 - Terminated(EORTC trail showed ... More >>TMZ & RT conferred significant survivial in this population) Less << - -
NCT01390909 - Completed - -
NCT03514524 Neuro-Degenerative Disease Not Applicable Enrolling by invitation September 2020 Belgium ... More >> Division of nuclear medicine and molecular imaging, University Hospital Leuven Leuven, Belgium, 3000 Less <<
NCT01549288 Infantile Spasms Phase 2 Phase 3 Withdrawn December 2013 India ... More >> Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital New Delhi, Delhi, India, 110001 Less <<
NCT01227902 Epilepsy Phase 3 Completed - -
NCT02362373 - Completed - -
NCT01227902 - Completed - -
NCT01685411 Acute Lymphoblastic Leukemia ... More >> Acute Myeloid Leukemia Myelodysplastic Syndrome Less << Not Applicable Recruiting September 2025 United States, Minnesota ... More >> Masonic Cancer Center, University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Margaret L. MacMillan, M.D.    612-626-2778    macmi002@umn.edu    Principal Investigator: Margaret L. MacMillan, M.D. Less <<
NCT01390909 - Completed - -
NCT03196466 - Recruiting June 2019 France ... More >> AP-HP Cochin Recruiting Paris, France, 75014 Contact: Jean-Marc Treluyer, M.D., PhD    + 00 1 58 41 28 85    jean-marc.treluyer@parisdescartes.fr Less <<
NCT02056236 Cardiac Arrest ... More >> Anoxic Encephalopathy Status Epilepticus Less << Not Applicable Recruiting September 2019 Belgium ... More >> Hôpital Erasme - Université libre de Bruxelles Recruiting Brussels, Lenniksebaan 808, Belgium, 1070 Contact: Fabio Taccone, MD PhD    0032-2 555 31 11    Fabio.Taccone@erasme.ulb.ac.be    Netherlands Radboud University Medical Center Recruiting Nijmegen, Geert Grooteplein-Zuid 10, Netherlands, 6525 GA Contact: Astrid Hoedemaekers, MD PhD    0031-24- 3611111    Astrid.Hoedemaekers@radboudumc.nl    Medisch Spectrum Twente Recruiting Enschede, Haaksbergerstraat 55, Netherlands, 7513 ER Contact: Michel van Putten, MD PhD    0031-53-4872810    m.j.a.m.vanputten@utwente.nl    University Medical Center Groningen Recruiting Groningen, Hanzeplein 1, Netherlands, 9700 RB Contact: Walter van den Bergh, MD PhD    0031-50-3616161    w.m.van.den.bergh@umcg.nl    St. Antonius Hospital Recruiting Nieuwegein, Koekoekslaan 1, Netherlands, 3430 EM Contact: Selma Tromp, MD PhD    0031-88-320 30 00    s.tromp1@antoniusziekenhuis.nl    Academic Medical Center Recruiting Amsterdam, Meibergdreef 9, Netherlands, 1105 AZ Contact: Janneke Horn, MD PhD    0031-20-566 9111    j.horn@amc.uva.nl    VieCuri Medical Centre Recruiting Venlo, Tegelseweg 210, Netherlands, 5912 BL Contact: Norbert Foudraine, MD PhD    0031-77-320 55 55    nfoudraine@viecuri.nl    Rijnstate Hospital Recruiting Arnhem, Wagnerlaan 55, Netherlands, 6815 AD Contact: Jeannette Hofmeijer, MD PhD    0031-88-0058877    jhofmeijer@rijnstate.nl    Maasstad Hospital Recruiting Rotterdam, Zuid-Holland, Netherlands, 3079 DZ Contact: Elsbeth Thomeer    0031 10 291 1911    ThomeerE@maasstadziekenhuis.nl Less <<
NCT02362373 Epilepsy Cont... More >>raception Less << Phase 4 Completed - United States, New York ... More >> Columbia University New York, New York, United States, 10032 Less <<
NCT00489281 Sickle Cell Disease Phase 2 Active, not recruiting December 2018 United States, Maryland ... More >> Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 Less <<
NCT01857934 Neuroblastoma Phase 2 Recruiting July 2021 United States, Tennessee ... More >> St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Wayne L. Furman, MD    866-278-5833    referralinfo@stjude.org    Principal Investigator: Wayne L. Furman, MD Less <<
NCT02429596 Epilepsy Phase 4 Unknown May 2015 Italy ... More >> Clinica Neurologica, Ospedali Riuniti Not yet recruiting Ancona, Italy Contact: Leandro Provinciali, MD       leandroprovinciali@gmail.com    Clinica Neurologica Amaducci, Policlinico di Bari Not yet recruiting Bari, Italy Contact: Angela La Neve, MD       centroepilessia@neurol.uniba.it    Principal Investigator: Angela La Neve, MD          U.S.C. Neurologia, Ospedali Riuniti Active, not recruiting Bergamo, Italy Dipartimento di Scienze Neurologiche, Università degli Studi di Bologna Recruiting Bologna, Italy Contact: Agostino Baruzzi, MD       agostino.baruzzi@unibo.it    Contact: Barbara Mostacci, MD       barbara.mostacci@unibo.it    Principal Investigator: Agostino Baruzzi, MD          Unità Operativa Complessa di Neurologia, Ospedale di Bellaria Recruiting Bologna, Italy Contact: Roberto Michelucci, MD       roberto.michelucci@ausl.bologna.it    Contact: Lilia Volpi, MD       lilia.volpi@ausl.bologna.it    Centro Regionale dell'Epilessia, Azienda Ospedaliera Spedali Civili Not yet recruiting Brescia, Italy Contact: Luisa Antonini, MD       luisa.antonini@spedalicivili.brescia.it    Azienda Ospedaliera, Policlinico Universitario Mater Domini Completed Catanzaro, Italy, 88100 Azienda Ospedaliera ospedali Riuniti Active, not recruiting Foggia, Italy Azienda Ospedaliera Universitaria Policlinico Gaetano Martino Not yet recruiting Messina, Italy Contact: Edoardo Spina, MD       espina@unime.it    Principal Investigator: Edoardo Spina, MD          Clinica Neurologica, Ospedale San Gerardo Not yet recruiting Monza, Italy Contact: Carlo Ferrarese, MD       carlo.ferrarese@unimib.it    Contact: Simone Beretta, MD       simone.beretta@unimib.it    Clinica Neurologica, Azienda Ospedaliero-Universitaria Maggiore della Carità Recruiting Novara, Italy Contact: Roberto Cantello, MD          Contact: Claudia Varrasi, MD       claudia.varrasi@libero.it    S.C. di Neurofisiopatologia, Centro di Riferimento Regionale Umbro per l'Epilessia Not yet recruiting Perugia, Italy Contact: Teresa Anna Cantisani, MD       cantisani@yahoo.com    UO di Neurologia, Azienda Ospedaliero Universitaria Pisana Active, not recruiting Pisa, Italy Centro Regionale Epilessie, Reggio Calabria e Università della Magna Graecia Recruiting Reggio Calabria, Italy Contact: Umberto Aguglia, MD       u.aguglia@tin.it    Contact: Sara Gasparini, MD          Dipartimento di Scienze Neurologiche, III Clinica Neurologica, Università "La Sapienza" Not yet recruiting Roma, Italy Contact: Anna Teresa Giallonardo, MD       annateresa.giallonardo@uniroma1.it    Unità Complessa di Neurologia, Ospedale SS. Giovanni e Paolo Not yet recruiting Venezia, Italy Contact: Francesco Paladin, MD Less <<
NCT00160615 Epilepsy, Partial PHASE3 COMPLETED 2007-01-17 -
NCT01521130 Benign Childhood Epilepsy With... More >> Centro-Temporal Spikes Less << PHASE1 COMPLETED 2025-07-17 Cincinnati Children's Hospital... More >>, Cincinnati, Ohio, 45229, United States Less <<
NCT01801072 Intracranial Aneurysms|Seizure PHASE4 COMPLETED 2023-10-06 University of Michigan Health ... More >>System, Ann Arbor, Michigan, 48109, United States Less <<
NCT00160550 Generalized Convulsive Epileps... More >>y Less << PHASE3 COMPLETED 2025-06-05 -
NCT00600509 Epilepsy PHASE2 COMPLETED 2025-07-03 -
NCT04004702 Alzheimer Disease PHASE2 NOT_YET_RECRUITING 2025-06-25 Walter Reed National Military ... More >>Medical Center, Bethesda, Maryland, 20889, United States Less <<
NCT05330390 Epilepsy|Diabetic Nephropathy UNKNOWN 2023-12-31 Second Hospital of Shandong Un... More >>iversity, Jinan, Shandong, 250033, China Less <<
NCT03054285 Seizures|Traumatic Brain Injur... More >>y Less << PHASE4 UNKNOWN 2021-04-01 Loyola University Medical Cent... More >>er, Maywood, Illinois, 60153, United States Less <<
NCT00150774 Generalized Convulsive Epileps... More >>y Less << PHASE3 COMPLETED 2025-12-04 -
NCT00175955 Dyskinesia, Medication-induced PHASE2 COMPLETED 2025-12-05 Antwerpen, Belgium|Bourgois, B... More >>elgium|Gonce, Belgium|Hulselmans, Belgium|Liège, Belgium|Roeselare, Belgium|Haralanov, Bulgaria Less <<
NCT00181116 Epilepsy PHASE4 COMPLETED 2025-09-06 Johns Hopkins Hospital, Baltim... More >>ore, Maryland, 21287, United States Less <<
NCT00150709 Epilepsy, Partial PHASE3 COMPLETED 2006-01-25 -
NCT00152373 Epilepsy, Partial PHASE3 COMPLETED 2025-05-05 -
NCT00643500 Epilepsy, Partial PHASE4 COMPLETED 2025-05-03 -
NCT00610454 Epilepsy PHASE2 COMPLETED 2025-08-04 -
NCT00307450 Parkinson's Disease PHASE4 COMPLETED 2025-07-09 Department of Neurology at the... More >> Technical University of Dresden, Dresden, 01307, Germany|Department of Neurology at the University of Leipzig, Leipzig, 04103, Germany Less <<
NCT00252954 Injuries, Spinal Cord|Pain PHASE4 COMPLETED 2025-12-08 Danish Pain Research Center, A... More >>arhus University Hospital, Aarhus, 8000, Denmark|Clinic for Spinal Cord Injuries, Rigshospitalet, Hornbaek, 3100, Denmark|The Spinal Cord Unit, Dept of Rheumatology, Viborg, 8800, Denmark Less <<
NCT00319605 Epilepsy COMPLETED 2025-07-06 Alcala De Henares, Spain|Alcaz... More >>ar De San Juan, Spain|Alcorcon, Spain|Alicante, Spain|Alzira Valencia, Spain|Avila, Spain|Badajoz, Spain|Barcelona, Spain|Benidorm, Spain|Caceres, Spain|Cadz, Spain|Castellon, Spain|Coruna, Spain|Cuenca, Spain|Elda, Spain|Eliana, Spain|Girona, Spain|Granada, Spain|Guadalajara, Spain|Hospitalet Del Llobregat, Spain|Langreo, Spain|Las Palmas, Spain|Leon, Spain|Lleida, Spain|Lorca Murcia, Spain|Lugo, Spain|Madrid, Spain|Malaga, Spain|Manzanares Ciudad Real, Spain|Manzanares, Spain|Mataro, Spain|Merida Badajoz, Spain|Mostoles, Spain|Murcia, Spain|Oviedo, Spain|Palencia, Spain|Palmar, Spain|Palmas de Gran Canaria, Spain|Pamplona, Spain|Pontevedra, Spain|Puerto Del Rosario, Spain|Roca Del Valles, Spain|Sabadell, Spain|Salamanca, Spain|San Fernando, Spain|Santa Cruz De Tenerife, Spain|Sevilla, Spain|Terrassa, Spain|Teruel, Spain|Toledo, Spain|Valencia, Spain|Vigo Pontevedra, Spain|Zamora, Spain|Zaragoza, Spain Less <<
NCT00361010 Epilepsy|Childhood Absence Epi... More >>lepsy|Seizures Less << COMPLETED 2025-12-07 The Cleveland Clinic Foundatio... More >>n, Cleveland, Ohio, 44195, United States|The Cleveland Clinic, Cleveland, Ohio, 44195, United States Less <<
NCT01974700 Intracranial Aneurysms|Seizure... More >>s Less << PHASE4 TERMINATED 2025-02-16 IU Health Methodist Hospital, ... More >>Indianapolis, Indiana, 46202, United States Less <<
NCT06442748 Seizures|Brain Tumors|Antiepil... More >>eptics|Levetiracetam Less << PHASE3 RECRUITING 2031-06-01 Tata Memorial Centre, Mumbai, ... More >>Maharashtra, 400012, India Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.88mL

1.18mL

0.59mL

29.38mL

5.88mL

2.94mL

58.75mL

11.75mL

5.88mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

Historical Records

Categories