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Chemical Structure| 6000-44-8 Chemical Structure| 6000-44-8
Chemical Structure| 6000-44-8

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Synonyms: Sodium glycinate

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Product Details of Sodium 2-aminoacetate

CAS No. :6000-44-8
Formula : C2H4NNaO2
M.W : 97.05
SMILES Code : O=C([O-])CN.[Na+]
Synonyms :
Sodium glycinate
MDL No. :MFCD00062543
InChI Key :WUWHFEHKUQVYLF-UHFFFAOYSA-M
Pubchem ID :4684308

Safety of Sodium 2-aminoacetate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of Sodium 2-aminoacetate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6000-44-8 ]

[ 6000-44-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6000-44-8 ]
  • [ 112108-73-3 ]
  • N-(5'-Chloro-4'-methyl-2'-nitrophenyl)glycine sodium salt [ No CAS ]
YieldReaction ConditionsOperation in experiment
1.005 g (37%) In water; N,N-dimethyl-formamide; N-(5'-Chloro-4'-methyl-2'-nitrophenyl)glycine sodium salt. To a stirred solution of <strong>[112108-73-3]2-chloro-4-fluoro-5-nitrotoluene</strong> (2.080 g, 10.97 mmol, as prepared above) in DMF (11.0 mL) at 70 C., was added dropwise, a solution of sodium glycinate (1.065 g, 10.97 mmol, Aldrich, used as received) in water (11.0 mL). The resulting suspension was stirred overnight at 70 C., cooled to room temperature, and the resulting red solid was filtered, washed with acetone (35 mL), and dried under vacuum to give 1.005 g (37%) of the pure (1 H NMR) title compound as a red powder; 1 H NMR (DMSO-d6): delta2.184 (s, 3H), 3.396 (d, 2H, J=4.2 Hz), 6.852 (s, 1H), 7.991 (s, 1H), 8.671 (s, 1H).
  • 2
  • [ 1345-25-1 ]
  • [ 6000-44-8 ]
  • [ 20150-34-9 ]
YieldReaction ConditionsOperation in experiment
With citric acid; In water; at 55 - 60℃; for 1.0h; One mole of ferrous oxide is reacted with two moles of sodium glycinate in the presence of citric acid in an aqueous solution to form ferrous bisglycinate. The ferrous bisglycinate is further reacted in a 1:1 molar ratio with citric acid to form ferrous bisglycinate citric acid chelate. Specifically, two moles of sodium glycinate (194.1 g) were dissolved in one liter of 0.5 M citric acid, and the mixture was brought to 55-60° C. Next, 1.0 mole (71.8 g) of ferrous oxide was added to the mixture, and the mixture was allowed to react for 1 hour forming ferrous bisglycinate. Next, one mole of citric acid (192.1 g) was added to the reaction mixture. After a 4 hour reaction time, the composition was cooled 40° C. and spray dried to obtain about 394.0 g of ferrous bisglycinate citrate at 100percent yield.
 

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