Upadacitinib (ABT-494) | JAK1 Inhibitor

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NCT05507580	Atopic Dermatitis	PHASE4	COMPLETED	2024-08-15	Holdsworth House Medical Pract... More >>ice /ID# 254028, Darlinghurst, New South Wales, 2010, Australia\|Premier Specialist /ID# 246150, Kogarah, New South Wales, 2217, Australia\|Veracity Clinical Research /ID# 246154, Woolloongabba, Queensland, 4102, Australia\|North Eastern Health Specialists /ID# 246153, Campbelltown, South Australia, 5074, Australia\|Skin Health Institute Inc /ID# 246146, Carlton, Victoria, 3053, Australia\|Cliniques Universitaires UCL Saint-Luc /ID# 245842, Woluwe-Saint-Lambert, Bruxelles-Capitale, 1200, Belgium\|Grand Hopital de Charleroi /ID# 245837, Charleroi, Hainaut, 6000, Belgium\|AZ Sint-Lucas /ID# 253708, Gent, Oost-Vlaanderen, 9000, Belgium\|Dermatologie Maldegem /ID# 245840, Maldegem, Oost-Vlaanderen, 9990, Belgium\|CHU de Liege /ID# 245839, Liege, 4000, Belgium\|UMHAT Alexandrovska EAD /ID# 246594, Sofiya, Sofia, 1431, Bulgaria\|Medical center Cordis /ID# 253310, Pleven, 5800, Bulgaria\|Acibadem City Clinic Tokuda University Hospital EAD /ID# 246395, Sofia, 1407, Bulgaria\|Ambulatory for Specialized Medical Care for skin and venereal diseases /ID# 247027, Sofia, 1407, Bulgaria\|Medical center EuroHealth /ID# 246305, Sofia, 1606, Bulgaria\|Medical Center Euroderma /ID# 246736, Sofiya, 1606, Bulgaria\|Dermatology Research Institute - Blackfoot Trail /ID# 246703, Calgary, Alberta, T2J 7E1, Canada\|Beacon Dermatology Inc /ID# 246705, Calgary, Alberta, T3A 2N1, Canada\|Rejuvenation Dermatology - Edmonton Downtown /ID# 256790, Edmonton, Alberta, T5J 3S9, Canada\|Alberta DermaSurgery Centre /ID# 247286, Edmonton, Alberta, T6G 1C3, Canada\|Dr. Chih-ho Hong Medical Inc. /ID# 246700, Surrey, British Columbia, V3R 6A7, Canada\|Lynde Institute for Dermatology /ID# 246699, Markham, Ontario, L3P 1X2, Canada\|SKiN Centre for Dermatology /ID# 246702, Peterborough, Ontario, K9J 5K2, Canada\|Private Practice - Dr. Kim Papp Clinical Research /ID# 246698, Waterloo, Ontario, N2J 1C4, Canada\|Beijing Friendship Hospital /ID# 247719, Beijing, Beijing, 100032, China\|Peking University Third Hospital /ID# 247842, Beijing, Beijing, 100191, China\|Dermatology Hospital of Southern Medical University /ID# 247951, Guangzhou, Guangdong, 510091, China\|The First Hospital of China Medical University /ID# 247686, Shenyang, Liaoning, 110001, China\|Huashan Hospital, Fudan University /ID# 247680, Shanghai, Shanghai, 200040, China\|Dermatologische Gemeinschaftspraxis Mahlow /ID# 245629, Blankenfelde-Mahlow, Brandenburg, 15831, Germany\|Klinikum Darmstadt /ID# 247028, Darmstadt, Hessen, 64283, Germany\|Universitaetsklinikum Frankfurt /ID# 245627, Frankfurt am Main, Hessen, 60590, Germany\|Studienzentrum an der Hase GbR Dr. Weyergraf/Dr. Frick/Thomas Heiber /ID# 245636, Bramsche, Niedersachsen, 49565, Germany\|Universitaetsklinikum Muenster /ID# 245623, Muenster, Nordrhein-Westfalen, 48149, Germany\|Fachklinik Bad Bentheim /ID# 245634, Bad Bentheim, Saarland, 48455, Germany\|Elbe Klinikum Buxtehude /ID# 245626, Buxtehude, 21614, Germany\|Universitaetsklinikum Carl Gustav Carus an der TU Dresden /ID# 248413, Dresden, 01307, Germany\|Derma Study Center Friedrichshafen GmbH /ID# 245640, Friedrichshafen, 88045, Germany\|Universitaetsklinikum Halle (Saale) /ID# 245637, Halle (Saale), 06120, Germany\|Dermatologikum Hamburg /ID# 245635, Hamburg, 20354, Germany\|Dermatologie Quist-BAG Dres. med. Quist PartG /ID# 245628, Mainz, 55128, Germany\|Gyongyosi Bugat Pal Korhaz /ID# 246422, Gyongyos, Heves, 3200, Hungary\|Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 246428, Kaposvár, Somogy, 7400, Hungary\|Clinexpert Kft /ID# 246427, Budapest, 1033, Hungary\|DERMA-B Egeszsegugyi es Szolgaltato - Debrecen - Gyepusor Utca /ID# 246426, Debrecen, 4031, Hungary\|Istituto Clinico Humanitas /ID# 246630, Rozzano, Milano, 20089, Italy\|Azienda Ospedaliera di Perugia /ID# 246632, Perugia, Umbria, 06129, Italy\|Duplicate_Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona /ID# 254355, Ancona, 60126, Italy\|ASST Spedali civili di Brescia /ID# 246631, Brescia, 25123, Italy\|Universita degli Studi Gabriele dAnnunzio /ID# 246629, Chieti, 66100, Italy\|Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 246634, Milan, 20122, Italy\|Miyata Dermatology Clinic /ID# 255491, Matsudo-Shi, Chiba, 271-0092, Japan\|Fukuoka University Hospital /ID# 255182, Fukuoka-shi, Fukuoka, 814-0180, Japan\|Takagi Dermatological Clinic Branch /ID# 255181, Obihiro-shi, Hokkaido, 080-0013, Japan\|Nomura Dermatology Clinic /ID# 255534, Yokohama-shi, Kanagawa, 221-0825, Japan\|Tohoku University Hospital /ID# 255183, Sendai-shi, Miyagi, 9808574, Japan\|Maruyama Dermatology Clinic /ID# 255441, Koto-ku, Tokyo, 136-0074, Japan\|Korea University Ansan Hospital /ID# 245653, Ansan-si, Gyeonggido, 15355, Korea, Republic of\|Soon Chun Hyang University Hospital Bucheon /ID# 245654, Bucheon-si, Gyeonggido, 14584, Korea, Republic of\|Chungang University Hospital /ID# 245655, Dongjak-gu, Gyeonggido, 06973, Korea, Republic of\|Ajou University Hospital /ID# 245652, Suwon-si, Gyeonggido, 16499, Korea, Republic of\|Seoul National University Hospital /ID# 245651, Seoul, Seoul Teugbyeolsi, 03080, Korea, Republic of\|Konkuk University Medical Center /ID# 245657, Seoul, Seoul Teugbyeolsi, 05030, Korea, Republic of\|Amphia Ziekenhuis /ID# 246397, Breda, Noord-Brabant, 4818 CK, Netherlands\|Amsterdam UMC, locatie AMC /ID# 245673, Amsterdam, Noord-Holland, 1105 AZ, Netherlands\|Greenlane Clinical Centre /ID# 246556, Epsom, Auckland, 1051, New Zealand\|Clinical Trials New Zealand /ID# 246557, Hamilton, Manawatu-Wanganui, 3204, New Zealand\|Aotearoa Clinical Trials /ID# 246559, Auckland, 1640, New Zealand\|Oftalmika sp. z o.o. /ID# 253429, Bydgoszcz, Kujawsko-pomorskie, 85-631, Poland\|MICS Centrum Medyczne Torun /ID# 245749, Torun, Kujawsko-pomorskie, 87-100, Poland\|Dermed Centrum Medyczne Sp. z o.o /ID# 246329, Lodz, Lodzkie, 90-265, Poland\|Santa Sp. z o.o. Santa Familia Centrum Badan, Profilaktyki i Leczenia /ID# 253872, Lodz, Lodzkie, 90-302, Poland\|Centrum Nowoczesnych Terapii Dobry Lekarz Sp. z o.o. /ID# 245836, Krakow, Malopolskie, 31-011, Poland\|CenterMed Krakow Sp. z o.o. /ID# 253940, Krakow, Malopolskie, 31-530, Poland\|Royalderm Agnieszka Nawrocka /ID# 245746, Warsaw, Mazowieckie, 02-962, Poland\|Klinika Ambroziak Sp. z o.o. /ID# 245748, Warszawa, Mazowieckie, 02-953, Poland\|Centrum Badan Klinicznych PI-House sp. z o.o. /ID# 245741, Gdansk, Pomorskie, 80-546, Poland\|Centrum Medyczne Pratia Gdynia /ID# 245835, Gdynia, Pomorskie, 81-338, Poland\|Silmedic Sp. z o.o. /ID# 253863, Katowice, Slaskie, 40-282, Poland\|Specjalistyczna Przychodnia Lekarska Alergo-Med sp. z o.o. /ID# 253846, Poznan, Wielkopolskie, 61-578, Poland\|Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej Alergologia Plus /ID# 253508, Poznań, Wielkopolskie, 60-693, Poland\|Hospital CUF Descobertas /ID# 245702, Lisboa, Regiao Autonoma Da Madeira, 1998-018, Portugal\|Centro Hospitalar Universitario do Porto, EPE - Hospital Santo Antonio /ID# 245701, Porto, Regiao Autonoma Da Madeira, 4099-001, Portugal\|Centro Hospitalar de Lisboa Central /ID# 246247, Lisbon, 1169-050, Portugal\|Centro Hospitalar Universitario de Sao Joao, EPE /ID# 245704, Porto, 4200-319, Portugal\|Univerzitna nemocnica Martin /ID# 246948, Martin, Zilinsky Kraj, 036 01, Slovakia\|Poliklinika Bezrucova (Cliniq s.r.o.) /ID# 247515, Bratislava, 811 09, Slovakia\|BeneDerma s.r.o. /ID# 247513, Bratislava, 841 04, Slovakia\|Hospital Universitario Germans Trias i Pujol /ID# 246320, Badalona, Barcelona, 08916, Spain\|Hospital Universitari de Bellvitge /ID# 246326, L'Hospitalet de Llobregat, Barcelona, 08907, Spain\|Hospital Universitario Puerta de Hierro - Majadahonda /ID# 253820, Majadahonda, Madrid, 28222, Spain\|Hospital General Universitario de Alicante Doctor Balmis /ID# 246270, Alicante, 03010, Spain\|Hospital Universitario Infanta Leonor /ID# 246272, Madrid, 28031, Spain\|Hospital Universitario Ramon y Cajal /ID# 246273, Madrid, 28034, Spain\|Complejo Hospitalario Universitario de Pontevedra /ID# 246323, Pontevedra, 36071, Spain\|Hospital Universitario Virgen del Rocio /ID# 253822, Sevilla, 41013, Spain\|Kaohsiung Chang Gung Memorial Hospital /ID# 245710, Kaohsiung City, Kaohsiung, 833, Taiwan\|Chung Shan Medical University Hospital /ID# 245707, Taichung, Keelung, 40201, Taiwan\|Taipei Municipal Wan Fang Hospital /ID# 245712, Taipei, Keelung, 116, Taiwan\|National Taiwan University Hospital /ID# 245711, Taipei City, Taipei, 100, Taiwan\|Mackay Memorial Hospital /ID# 245713, Taipei City, 104, Taiwan\|Linkou Chang Gung Memorial Hospital /ID# 245709, Taoyuan City, 333, Taiwan\|University Hospital Southampton NHS Foundation Trust /ID# 246393, Southampton, Hampshire, SO16 6YD, United Kingdom\|NHS Greater Glasgow and Clyde /ID# 246253, Glasgow, Scotland, G12 0XH, United Kingdom\|NHS Lothian /ID# 246245, Edinburgh, EH3 9HE, United Kingdom\|Leeds Teaching Hospitals NHS Trust /ID# 246241, Leeds, LS9 7TF, United Kingdom Less <<
NCT06144567	Psoriatic Arthritis		NOT_YET_RECRUITING	2025-06-26	Instituto de Investigación San... More >>itaria Fundación Jiménez Díaz, Madrid, 28040, Spain Less <<
NCT06274996	Inflammatory Bowel Diseases		COMPLETED	2023-12-31	the Sixth Affiliated Hospital ... More >>of Sun Yat-Sen University, Guangzhou, Guangdong, 510655, China Less <<
NCT05782907	Ulcerative Colitis	PHASE3	RECRUITING	1933-10-01	Phoenix Children's Hospital /I... More >>D# 250135, Phoenix, Arizona, 85016-7710, United States\|Arkansas Children's Hospital /ID# 250106, Little Rock, Arkansas, 72202, United States\|Kindred Medical Institute - Corona /ID# 255484, Corona, California, 92879-3104, United States\|UCSF Benioff Children's Hospital - Oakland /ID# 255067, Oakland, California, 94609, United States\|Children's Hospital Colorado - Aurora /ID# 250110, Aurora, Colorado, 80045, United States\|Nemours/Alfred duPont Hospital for Children /ID# 255483, Wilmington, Delaware, 19803, United States\|Childrens Healthcare of Atlanta - Center for Advanced Pediatrics /ID# 255069, Atlanta, Georgia, 30329, United States\|OSF St. Francis Medical Center /ID# 256968, Peoria, Illinois, 61637-0001, United States\|Massachusetts General Hospital /ID# 250142, Boston, Massachusetts, 02114, United States\|NYU Langone Hospital - Long Island /ID# 250136, Mineola, New York, 11501, United States\|The Mount Sinai Hospital /ID# 250141, New York, New York, 10029, United States\|Univ NC Chapel Hill /ID# 254541, Chapel Hill, North Carolina, 27514-4220, United States\|Levine Children's Hospital /ID# 250131, Charlotte, North Carolina, 28203, United States\|UH Cleveland Medical Center /ID# 250134, Cleveland, Ohio, 44106, United States\|Children's Hospital of Philadelphia - Main /ID# 258773, Philadelphia, Pennsylvania, 19104-4319, United States\|Children's Specialty Group /ID# 256966, Norfolk, Virginia, 23507, United States\|Children's Hospital at Westmead /ID# 255556, Westmead, New South Wales, 2145, Australia\|Queensland Children's Hospital /ID# 261032, South Brisbane, Queensland, 4101, Australia\|Monash Health - Monash Medical Centre /ID# 254726, Clayton, Victoria, 3168, Australia\|Perth Children'S Hospital /ID# 254727, Perth, Western Australia, 6009, Australia\|Universitair Ziekenhuis Antwerpen /ID# 251184, Edegem, Antwerpen, 2650, Belgium\|Universitair Ziekenhuis Leuven /ID# 251185, Leuven, Vlaams-Brabant, 3000, Belgium\|Hospital Pequeno Príncipe /ID# 251911, Curitiba, Parana, 80250-060, Brazil\|Hospital e Maternidade Celso Pierro - PUC-Campinas /ID# 251912, Campinas, Sao Paulo, 13034-685, Brazil\|Rocco & Nazato Servicos Medicos /ID# 251910, S?o Paulo, Sao Paulo, 04543-011, Brazil\|UMHAT Sveti Georgi /ID# 251949, Plovdiv, 4002, Bulgaria\|Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 251285, Sofiya, 1606, Bulgaria\|UMHAT Sveta Marina /ID# 251948, Varna, 9010, Bulgaria\|Alberta Health Services /ID# 252088, Edmonton, Alberta, T6G 1C9, Canada\|IWK Health Center /ID# 250943, Halifax, Nova Scotia, B3K 6R8, Canada\|Hospital for Sick Children /ID# 250945, Toronto, Ontario, M5G 1X8, Canada\|Fakultní nemocnice v Motole /ID# 251955, Prague, Praha 5, 150 06, Czechia\|CHU Bordeaux - Hopital Pellegrin /ID# 253182, Bordeaux, Nouvelle-Aquitaine, 33076, France\|HCL - Hopital Femme Mere Enfant /ID# 251502, Bron CEDEX, Rhone, 69677, France\|AP-HP - Hopital Necker /ID# 251658, Paris, 75015, France\|Hopitaux de Paris (AP-HP) - Hopital Robert Debre - CHU /ID# 252069, Paris, 75019, France\|CHU Toulouse - Hopital Paule de Viguier /ID# 252070, Toulouse, 31059, France\|Dr. von Haunerschen Kinderspital /ID# 251440, Muenchen, Bayern, 80337, Germany\|Universitaetsklinikum Muenster /ID# 256763, Muenster, Nordrhein-Westfalen, 48149, Germany\|Agia Sofia Hospital /ID# 250697, Athens, Attiki, 11527, Greece\|University General Hospital of Heraklion PA.G.N.I /ID# 250696, Heraklion, Kriti, 71500, Greece\|Debreceni Egyetem-Klinikai Kozpont /ID# 251835, Debrecen, Hajdu-Bihar, 4032, Hungary\|Semmelweis Egyetem /ID# 251083, Budapest, 1085, Hungary\|Schneider Children's Medical Center /ID# 254833, Petah Tikva, HaMerkaz, 4920235, Israel\|Shaare Zedek Medical Center /ID# 254832, Jerusalem, Yerushalayim, 91031, Israel\|Azienda Ospedaliero Universitaria Meyer /ID# 251624, Florence, Firenze, 50139, Italy\|Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 251625, Rome, Roma, 00161, Italy\|Ospedale Maggiore Carlo Alberto Pizzardi /ID# 251626, Bologna, 40133, Italy\|Tsujinaka Hospital Kashiwanoha /ID# 251930, Kashiwa-shi, Chiba, 277-0871, Japan\|Kurume University Hospital /ID# 251927, Kurume-shi, Fukuoka, 830-0011, Japan\|Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 251928, Sapporo-shi, Hokkaido, 060-0033, Japan\|Miyagi Children's Hospital /ID# 251931, Sendai-shi, Miyagi, 989-3126, Japan\|Osaka Women's and Children's Hospital /ID# 252397, Izumi-Shi, Osaka, 594-1101, Japan\|Osaka General Medical Center /ID# 253678, Osaka-shi, Osaka, 558-8558, Japan\|Saitama Children's Medical Center /ID# 252362, Saitama-shi, Saitama, 330-8777, Japan\|Institute of Science Tokyo Hospital /ID# 251929, Bunkyo-ku, Tokyo, 113-8519, Japan\|Tokyo Metropolitan Children's Medical Center /ID# 252477, Fuchu-shi, Tokyo, 183-8561, Japan\|National Center for Child Health and Development /ID# 251926, Setagaya-ku, Tokyo, 157-8535, Japan\|Seoul National University Hospital /ID# 252024, Seoul, Seoul Teugbyeolsi, 03080, Korea, Republic of\|Samsung Medical Center /ID# 252023, Seoul, Seoul Teugbyeolsi, 06351, Korea, Republic of\|Kyungpook National University Chilgok Hospital /ID# 252663, Daegu, 41404, Korea, Republic of\|Amsterdam UMC, locatie AMC /ID# 250845, Amsterdam, Noord-Holland, 1105 AZ, Netherlands\|Universitair Medisch Centrum Groningen /ID# 252003, Groningen, 9713 GZ, Netherlands\|Christchurch Hospital /ID# 254703, Christchurch, Canterbury, 8011, New Zealand\|Starship Child Health /ID# 254702, Auckland, 0629, New Zealand\|Gastromed Sp. z o.o /ID# 251290, Torun, Kujawsko-pomorskie, 87-100, Poland\|Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 251289, Warszawa, Mazowieckie, 04-730, Poland\|Clinical Research Puerto Rico /ID# 266477, San Juan, 00909-1711, Puerto Rico\|Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 252105, Ferrol, A Coruna, 15405, Spain\|Hospital Sant Joan de Deu /ID# 251194, Esplugues de Llobregat, Barcelona, 08950, Spain\|Hospital Universitario Vall d'Hebron /ID# 252104, Barcelona, 08035, Spain\|Hospital Regional Universitario de Malaga /ID# 251193, Malaga, 29011, Spain\|National Taiwan University Hospital /ID# 251650, Taipei City, Taipei, 100, Taiwan\|Linkou Chang Gung Memorial Hospital /ID# 251654, Taoyuan City, 333, Taiwan\|Sheffield Children's Hospital NHS Foundation Trust /ID# 251600, Sheffield, England, S10 2TH, United Kingdom\|Barts Health NHS Trust /ID# 251917, London, Greater London, E1 2ES, United Kingdom\|Great Ormond Street Children's Hospital /ID# 252126, London, Greater London, WC1N 3HZ, United Kingdom\|University Hospital Southampton NHS Foundation Trust /ID# 252097, Southampton, Hampshire, SO16 6YD, United Kingdom\|Birmingham Women's and Children's NHS Foundation Trust /ID# 253072, Birmingham, B4 6NH, United Kingdom Less <<
NCT06780683	Inflammatory Bowel Disease\|Cro... More >>hn's Disease\|Ulcerative Colitis Less <<		RECRUITING	2028-12-31	The Second Affiliated Hospital... More >> of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, China\|Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China\|Meizhou People's Hospital, Meizhou, Guangdong, 514000, China\|The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong, 518000, China\|Liuzhou People's Hospital, Liuzhou, Guangxi, 545000, China\|Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, 530000, China Less <<
NCT04159597	Atopic Dermatitis (AD)		NO_LONGER_AVAILABLE	-	-
NCT06773403	Prurigo Nodularis	PHASE4	RECRUITING	2025-01-26	Eczema Treatment Center of New... More >> Jersey, East Windsor, New Jersey, 08520, United States Less <<
NCT05094128	Axial Spondylarthritis (r-axSp... More >>A) Less <<		RECRUITING	2025-06-26	ACURA Rheumazentrum Baden-Bade... More >> /ID# 249751, Baden-baden, Baden-Wuerttemberg, 76530, Germany\|Heilig, Heidelberg, DE /ID# 240492, Heidelberg, Baden-Wuerttemberg, 69120, Germany\|Rheumatologische Schwerpunktpraxis /ID# 245392, Stuttgart, Baden-Wuerttemberg, 70372, Germany\|Praxis Dr. Haas /ID# 242982, Tuebingen, Baden-Wuerttemberg, 72072, Germany\|Praxis Dr. Rinaldi /ID# 242984, Ulm, Baden-Wuerttemberg, 89073, Germany\|Praxis K. Pagel /ID# 240490, Hoppegarten, Brandenburg, 15366, Germany\|Rheumahaus Studien GbR, Potsdam, DE /ID# 245231, Potsdam, Brandenburg, 14467, Germany\|Praxis Dr. Sabine Reckert /ID# 245142, Potsdam, Brandenburg, 14469, Germany\|Fachpraxis fuer Rheumatologie und Osteologie /ID# 243358, Bruchhausen-Vilsen, Niedersachsen, 27305, Germany\|Stille, Hanover, DE /ID# 252222, Hannover, Niedersachsen, 30161, Germany\|Praxis. F. Bigdeli-Wilshusen /ID# 272904, Hanover, Niedersachsen, 30173, Germany\|Krankenhaus Porz am Rhein /ID# 243765, Cologne, Nordrhein-Westfalen, 51149, Germany\|Rheumazentrum Ruhrgebiet /ID# 240460, Herne, Nordrhein-Westfalen, 44649, Germany\|Beyer, Kaiserslautern, DE /ID# 240444, Kaiserslautern, Rheinland-Pfalz, 67659, Germany\|Krankenhaus der Barmherzigen Brüder Trier /ID# 240524, Trier, Rheinland-Pfalz, 54292, Germany\|Praxis Bernd Mueller /ID# 240488, Homburg, Saarland, 66424, Germany\|Rheumapraxis Dr. Prothmann /ID# 240671, Püttlingen, Saarland, 66346, Germany\|Praxis Dr. Liebhaber /ID# 240480, Halle, Sachsen-Anhalt, 06128, Germany\|Aurich & Sieburg, Magdeburg /ID# 240518, Magdeburg, Sachsen-Anhalt, 39104, Germany\|Med Versorgungszentrum AGILOMED /ID# 240481, Chemnitz, Sachsen, 09130, Germany\|Hamann & Teich & Boche,Leipzig /ID# 240445, Leipzig, Sachsen, 04109, Germany\|Praxis internistische Rheumatologie /ID# 240515, Leipzig, Sachsen, 04129, Germany\|Rheumatologische Praxis Dr. Jochen Walter /ID# 250263, Rendsburg, Schleswig-Holstein, 24768, Germany\|MVZ Ambulantes Rheumazentrum Erfurt /ID# 244448, Erfurt, Thueringen, 99096, Germany\|Rheumapraxis Weimar /ID# 268387, Weimar, Thueringen, 99427, Germany\|Kupka & Kupka, Altenburg, DE /ID# 240479, Altenburg, 04600, Germany\|Marycz, Amberg, DE /ID# 240483, Amberg, 92224, Germany\|Rheumapraxis am Webereck /ID# 240454, Augsburg, 86157, Germany\|Praxis S. Bresgulewski /ID# 240662, Bad Bertrich, 56864, Germany\|Kerckhoff Klinik /ID# 252219, Bad Nauheim, 61231, Germany\|Rheumapraxis Berlin /ID# 242987, Berlin, 12435, Germany\|Praxis Dr. med. Angela Seifert /ID# 245107, Berlin, 12555, Germany\|Praxis Dr. Silke Zinke /ID# 240526, Berlin, 13055, Germany\|Krankenhaus Waldfriede /ID# 268389, Berlin, 14163, Germany\|Eisterhues, Braunschweig, DE /ID# 239438, Braunschweig, 38100, Germany\|MVZ Herzogin Elisabeth Hospital /ID# 267983, Brunswick, 38114, Germany\|Dr. Walberer /ID# 249752, Burglengenfeld, 93133, Germany\|Dres. Schuh /ID# 240498, Coburg, 96450, Germany\|Dres. Karger/Baerlecken /ID# 240442, Cologne, 50996, Germany\|MVZ-Medizinisches Versorgungszentrum Daun GmbH /ID# 254839, Daun, 54550, Germany\|Kreiskrankenhaus Demmin /ID# 240451, Demmin, 17109, Germany\|Rheumatologisches MVZ Dresden /ID# 240516, Dresden, 01109, Germany\|Praxis Dilltal /ID# 240520, Ehringshausen, 35630, Germany\|Dr. Bestler /ID# 251860, Erfurt, 99096, Germany\|Michael Mueller, Freiberg, DE /ID# 240489, Freiberg, 09599, Germany\|Praxis Dres. Sensse/Sensse /ID# 240517, Gifhorn, 38518, Germany\|Dr. Heintz /ID# 254037, Hamburg, 22391, Germany\|Dres. Weinhardt/Knobel/Doepfer /ID# 248195, Hamburg, 22523, Germany\|Medizinische Hochschule Hannover /ID# 262814, Hannover, 30625, Germany\|Zentrum fuer Rheumatologie und Schmerzmedizin /ID# 244370, Hanover, 30159, Germany\|Wernicke, Hohen Neuendorf, DE /ID# 250626, Hohen Neuendorf, 16540, Germany\|Kremers, Juelich, DE /ID# 243357, Juelich, 52428, Germany\|Dr. Bolze, Ludwigshafen, DE /ID# 251012, Ludwigshafen, 67069, Germany\|Praxis Dr. Annekatrin Rossbach /ID# 240495, Mansfeld / Gro??rner, 06343, Germany\|Harmuth, Marktredwitz, DE /ID# 240455, Marktredwitz, 95615, Germany\|RHIO Forschungsinstitut /ID# 240525, Meerbusch, 40668, Germany\|Prof-med-stud.de /ID# 240458, Munich, 80935, Germany\|Rheumatologische Facharztpraxis /ID# 240477, Naumburg (Saale), 06618, Germany\|Praxis Dr. med Thilo Klopsch /ID# 240461, Neubrandenburg, 17033, Germany\|Praxis Hein & Gess /ID# 240456, Nienburg, 31582, Germany\|MVZ für Rheumatologie Dr. M. Welcker /ID# 240521, Planegg, 82152, Germany\|Baumann & Lang, Plauen, DE /ID# 244369, Plauen, 08523, Germany\|Rheumazentrum Ratingen /ID# 240465, Ratingen, 40882, Germany\|Melzer, Seesen, DE /ID# 240484, Seesen, 38723, Germany\|Barmherzige Bruder MVZ Klinikum Straubing GmbH /ID# 240523, Straubing, 94315, Germany\|Rheumathologie Ulm /ID# 240494, Ulm, 89073, Germany\|Praxis F. Schattenberg /ID# 257646, Waren (Müritz), 17192, Germany\|Krankenhaus St. Josef /ID# 249747, Wuppertal, 42105, Germany\|Praxis Barmen /ID# 240449, Wuppertal, 42285, Germany\|Fricke-Wagner, Zwickau, DE /ID# 240452, Zwickau, 08060, Germany Less <<
NCT02782663	Crohn's Disease (CD)	PHASE2	ACTIVE_NOT_RECRUITING	2025-09-17	UC San Diego Health System /ID... More >># 150041, La Jolla, California, 92037, United States\|Univ California, San Francisco /ID# 149987, San Francisco, California, 94143-2204, United States\|Duplicate_University of Florida - Archer /ID# 150033, Gainesville, Florida, 32610, United States\|The Ctr for Gastro Disorders /ID# 150012, Hollywood, Florida, 33021, United States\|Nature Coast Clinical Research - Inverness /ID# 149975, Inverness, Florida, 34452-4717, United States\|Gastroenterology Associates of Central Georgia, LLC /ID# 149870, Macon, Georgia, 31201, United States\|GI Specialists of GA, PC /ID# 150015, Marietta, Georgia, 30060, United States\|Cotton O'Neil Clinical Research Center, Digestive Health /ID# 149900, Topeka, Kansas, 66606, United States\|Duplicate_University of Louisville /ID# 149884, Louisville, Kentucky, 40202, United States\|Investigative Clinical Research /ID# 149886, Annapolis, Maryland, 21401, United States\|Charm City Research Group /ID# 150040, Towson, Maryland, 21204, United States\|Clin Res Inst of Michigan, LLC /ID# 150008, Chesterfield, Michigan, 48047, United States\|Mayo Clinic - Rochester /ID# 149894, Rochester, Minnesota, 55905-0001, United States\|Kansas City Research Institute /ID# 149888, Kansas City, Missouri, 64131, United States\|Washington University-School of Medicine /ID# 149899, Saint Louis, Missouri, 63110, United States\|NYU Langone Long Island Clinical Research Associates /ID# 149976, Lake Success, New York, 11042, United States\|Weill Cornell Medicine/NYP /ID# 149895, New York, New York, 10021-4872, United States\|Univ NC Chapel Hill /ID# 149982, Chapel Hill, North Carolina, 27514-4220, United States\|University of Cincinnati /ID# 149977, Cincinnati, Ohio, 45267-0585, United States\|Options Health Research, LLC /ID# 150010, Tulsa, Oklahoma, 74104, United States\|Texas Digestive Disease Consultants - Southlake /ID# 149869, Southlake, Texas, 76092, United States\|Texas Digestive Disease Consultants - Southlake /ID# 149989, Southlake, Texas, 76092, United States\|Aspen Clinical Research /ID# 150020, Orem, Utah, 84058, United States\|University of Virginia /ID# 149881, Charlottesville, Virginia, 22908, United States\|Virginia Mason Hospital & Medical Center /ID# 150042, Seattle, Washington, 98101, United States\|University of Washington /ID# 149988, Seattle, Washington, 98109, United States\|Wisconsin Center for Advanced Research /ID# 149863, Milwaukee, Wisconsin, 53215, United States\|CHU de Liege /ID# 149912, Liege, 4000, Belgium\|University of Alberta Hospital /ID# 149873, Edmonton, Alberta, T6G 2B7, Canada\|University of British Columbia (UBC) - Gordon and Leslie Diamond Health Care Ce /ID# 149876, Vancouver, British Columbia, V5Z 1M9, Canada\|GIRI Gastrointestinal Research Institute /ID# 149878, Vancouver, British Columbia, V6Z 2K5, Canada\|Toronto Digestive Disease Associates, Inc. /ID# 149877, Vaughan, Ontario, L4L 4Y7, Canada\|Royal Victoria Hospital / McGill University Health Centre /ID# 149871, Montreal, Quebec, H4A 3J1, Canada\|Hepato-Gastroenterologie HK, s.r.o. /ID# 149882, Hradec Kralove, 500 12, Czechia\|Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 149890, Hvidovre, Hovedstaden, 2650, Denmark\|Duplicate_Aarhus University Hospital /ID# 149919, Aarhus N, Midtjylland, 8200, Denmark\|CHRU Nancy - Hopitaux de Brabois /ID# 149896, Vandoeuvre-les-Nancy, Meurthe-et-Moselle, 54500, France\|CHRU Lille - Hopital Claude Huriez /ID# 149897, Lille, Nord, 59037, France\|CHU Amiens-Picardie Site Sud /ID# 149921, Amiens CEDEX 1, Somme, 80054, France\|Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 149936, Kiel, Schleswig-Holstein, 24105, Germany\|DRK Kliniken Berlin Westend /ID# 149905, Berlin, 14050, Germany\|Medizinisches Versorgungszentrum Portal 10 /ID# 149930, Muenster, 48155, Germany\|Magyar Elhizastudomanyi Kozpont Kft. /ID# 149907, Budapest, 1124, Hungary\|Yitzhak Shamir Medical Center /ID# 149943, Zerifin, HaMerkaz, 70300, Israel\|The Chaim Sheba Medical Center /ID# 149945, Ramat Gan, Tel-Aviv, 5265601, Israel\|Rabin Medical Center /ID# 149942, Haifa, 4941492, Israel\|University of Catanzaro /ID# 149927, Catanzaro, Calabria, 88100, Italy\|IRCCS Azienda Ospedaliero-Universitaria di Bologna /ID# 149958, Bologna, 40138, Italy\|Amsterdam UMC, locatie AMC /ID# 149932, Amsterdam, Noord-Holland, 1105 AZ, Netherlands\|Universitair Medisch Centrum Utrecht /ID# 149933, Utrecht, 3584 CX, Netherlands\|Dunedin Hospital /ID# 149964, Otago, 9016, New Zealand\|Lovisenberg Diakonale Sykehus /ID# 149967, Oslo, 0440, Norway\|Santa Sp. z o.o. Santa Familia Centrum Badan, Profilaktyki i Leczenia /ID# 149979, Lodz, Lodzkie, 90-302, Poland\|Panstwowy Instytut Medyczny MSWiA w Warszawie /ID# 149978, Warszawa, Mazowieckie, 02-507, Poland\|Cabinet Particular Policlinic Algomed /ID# 149993, Timi?oara, 300002, Romania\|Duplicate_KM Management, spol. s.r.o. /ID# 149949, Nitra, Nitriansky Kraj, 949 01, Slovakia\|Gastro I., s.r.o. /ID# 149948, Pre?ov, Presovsky Kraj, 080 01, Slovakia\|Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 149996, Ferrol, A Coruna, 15405, Spain\|Hospital Universitario La Paz /ID# 149997, Madrid, 28046, Spain\|Oxford University Hospitals NHS Foundation Trust /ID# 149963, Oxford, Oxfordshire, OX3 9DU, United Kingdom\|Duplicate_Manchester University NHS Foundation Trust /ID# 150006, Manchester, M13 9WL, United Kingdom Less <<
NCT06498167	Inflammatory Disease\|Drug Side... More >> Effect\|Drug Use\|Adverse Drug Event\|Adverse Drug Reaction\|Safety Issues Less <<		RECRUITING	2024-12-31	Unidade Local de Saúde de Sant... More >>o António, E.P.E., Porto, 4050-366, Portugal\|Unidade Local de Saúde de S?o Jo?o, E.P.E., Porto, 4200-319, Portugal\|Unidade Local de Saúde de Gaia/Espinho, E.P.E., Porto, 4434-502, Portugal Less <<
NCT03725007	Juvenile Idiopathic Arthritis ... More >>(JIA) Less <<	PHASE1	ACTIVE_NOT_RECRUITING	2027-05-05	Ann & Robert H Lurie Children'... More >>s Hospital of Chicago /ID# 211162, Chicago, Illinois, 60611, United States\|Duplicate_University of Louisville /ID# 202896, Louisville, Kentucky, 40202, United States\|Boston Children's Hospital /ID# 202993, Boston, Massachusetts, 02115, United States\|Cincinnati Childrens Hospital Medical Center /ID# 209697, Cincinnati, Ohio, 45229, United States\|Randall Children's Hospital /ID# 213609, Portland, Oregon, 97227-1654, United States\|Children's Hospital of Philadelphia /ID# 209617, Philadelphia, Pennsylvania, 19146-2305, United States\|Children's Hospital of Pittsburgh of UPMC /ID# 202994, Pittsburgh, Pennsylvania, 15224-1334, United States\|Seattle Children's Hospital /ID# 203003, Seattle, Washington, 98105, United States\|Alberta Children's Hospital /ID# 251738, Calgary, Alberta, T3B 6A8, Canada\|British Columbia Children and Women's Hospital and Health Centre /ID# 251736, Vancouver, British Columbia, V6H 3N1, Canada\|Montreal Children's Hospital /ID# 251252, Montreal, Quebec, H4A 3J1, Canada\|St. Josef-Stift Sendenhorst /ID# 244740, Sendenhorst, Nordrhein-Westfalen, 48324, Germany\|PRI - Pediatric Rheumatology Research Institute /ID# 205954, Bad Bramstedt, Schleswig-Holstein, 24576, Germany\|Helios Klinikum Berlin-Buch /ID# 206859, Berlin, 13125, Germany\|Hamburger Zentrum fuer Kinder- und Jugendrheumatologie /ID# 206571, Hamburg, 22081, Germany\|Asklepios Klinik Sankt Augustin /ID# 203264, Sankt Augustin, 53757, Germany\|Semmelweis Egyetem /ID# 208970, Budapest, 1085, Hungary\|The Chaim Sheba Medical Center /ID# 222370, Ramat Gan, Tel-Aviv, 5265601, Israel\|IRCCS Ospedale Pediatrico Bambino Gesu /ID# 203835, Rome, Roma, 00165, Italy\|Aichi Children's Health and Medical Center /ID# 248327, Obu-shi, Aichi, 474-8710, Japan\|Hyogo Prefectural Kobe Children's Hospital /ID# 246582, Kobe-shi, Hyogo, 650-0047, Japan\|Kagoshima University Hospital /ID# 246501, Kagoshima-shi, Kagoshima, 890-8520, Japan\|St. Marianna University Hospital /ID# 246478, Kawasaki-shi, Kanagawa, 216-8511, Japan\|Miyagi Children's Hospital /ID# 246734, Sendai-shi, Miyagi, 989-3126, Japan\|Niigata University Medical & Dental Hospital /ID# 247246, Niigata-shi, Niigata, 951-8520, Japan\|Tokyo Medical And Dental University Hospital /ID# 246500, Bunkyo-ku, Tokyo, 113-8519, Japan\|Centro de Reumatologia Pediatrico de Puerto Rico /Id# 204406, Bayamon, 00959, Puerto Rico\|GCM Medical Group PSC /ID# 211702, San Juan, 00917-3104, Puerto Rico\|Mindful Medical Research /ID# 204488, San Juan, 00918-3756, Puerto Rico\|Hospital Sant Joan de Deu /ID# 203915, Esplugues de Llobregat, Barcelona, 08950, Spain\|Hospital Infantil Universitario Nino Jesus /ID# 206466, Madrid, 28009, Spain\|Hospital Universitario Ramon y Cajal /ID# 203917, Madrid, 28034, Spain\|Hospital Universitario La Paz /ID# 203927, Madrid, 28046, Spain\|Hospital Universitario y Politecnico La Fe /ID# 203914, Valencia, 46026, Spain\|Queen Silvia Children's Hosp /ID# 251145, Gothenburg, Vastra Gotalands Lan, 416 85, Sweden Less <<
NCT06332534	Crohn's Disease	PHASE3	RECRUITING	1934-12-01	OSF St. Francis Medical Center... More >> /ID# 262192, Peoria, Illinois, 61637-0001, United States\|Indiana University Health Riley Hospital for Children /ID# 262215, Indianapolis, Indiana, 46202, United States\|MNGI Digestive Health, P. A. /ID# 262204, Minneapolis, Minnesota, 55413-2195, United States\|Icahn School of Medicine at Mount Sinai /ID# 262216, New York, New York, 10029, United States\|UH Cleveland Medical Center /ID# 262188, Cleveland, Ohio, 44106, United States\|Children's Hospital at Westmead /ID# 262350, Westmead, New South Wales, 2145, Australia\|Queensland Children's Hospital /ID# 262351, South Brisbane, Queensland, 4101, Australia\|Monash Health - Monash Medical Centre /ID# 262878, Clayton, Victoria, 3168, Australia\|Cliniques Universitaires UCL Saint-Luc /ID# 261741, Woluwe-Saint-Lambert, Bruxelles-Capitale, 1200, Belgium\|Universitair Ziekenhuis Leuven /ID# 261740, Leuven, Vlaams-Brabant, 3000, Belgium\|CHR de la Citadelle /ID# 261749, Liege, 4000, Belgium\|Hospital Pequeno Príncipe /ID# 262600, Curitiba, Parana, 80250-060, Brazil\|Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 262601, Porto Alegre, Rio Grande Do Sul, 90020-090, Brazil\|Rocco & Nazato Servicos Medicos /ID# 262485, S?o Paulo, Sao Paulo, 04543-011, Brazil\|UMHAT Sveti Georgi /ID# 262590, Plovdiv, 4002, Bulgaria\|Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 262589, Sofiya, 1606, Bulgaria\|Guangzhou Medical University Affiliated Women and Children's Medical Center /ID# 262596, Guangzhou, Guangdong, 510620, China\|Hospices Civils de Lyon - H?pital Femme Mère Enfant /ID# 263422, Bron, Rhone, 69500, France\|CHU de CAEN - Hopital de la Cote de Nacre /ID# 262311, Caen, 14033, France\|General Hospital of Chest Diseases of Athens SOTIRIA /ID# 261790, Athens, Attiki, 11527, Greece\|University General Hospital of Heraklion PA.G.N.I /ID# 261791, Heraklion, Kriti, 71500, Greece\|Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 262384, San Giovanni Rotondo, Foggia, 71013, Italy\|Azienda Ospedaliera Universitaria Gaetano Martino /ID# 262380, Messina, 98125, Italy\|Tsujinaka Hospital Kashiwanoha /ID# 262454, Kashiwa-shi, Chiba, 277-0871, Japan\|Kurume University Hospital /ID# 262455, Kurume-shi, Fukuoka, 830-0011, Japan\|Miyagi Children's Hospital /ID# 262459, Sendai-shi, Miyagi, 989-3126, Japan\|Osaka Women's and Children's Hospital /ID# 262549, Izumi-Shi, Osaka, 594-1101, Japan\|Saga University Hospital /ID# 262753, Saga-shi, Saga, 849-8501, Japan\|Saitama Children's Medical Center /ID# 262461, Saitama-shi, Saitama, 330-8777, Japan\|Institute of Science Tokyo Hospital /ID# 262510, Bunkyo-ku, Tokyo, 113-8519, Japan\|Tokyo Metropolitan Children's Medical Center /ID# 262550, Fuchu-shi, Tokyo, 183-8561, Japan\|National Center for Child Health and Development /ID# 262456, Setagaya-ku, Tokyo, 157-8535, Japan\|Toyama Prefectural Central Hospital /ID# 262739, Toyama-shi, Toyama, 930-8550, Japan\|Seoul National University Hospital /ID# 262324, Seoul, Seoul Teugbyeolsi, 03080, Korea, Republic of\|Yonsei University Health System Severance Hospital /ID# 262721, Seoul, Seoul Teugbyeolsi, 03722, Korea, Republic of\|Samsung Medical Center /ID# 262323, Seoul, Seoul Teugbyeolsi, 06351, Korea, Republic of\|Christchurch Hospital /ID# 262577, Christchurch, Canterbury, 8011, New Zealand\|Starship Child Health /ID# 262576, Auckland, 0629, New Zealand\|Gastromed Sp. z o.o /ID# 262367, Torun, Kujawsko-pomorskie, 87-100, Poland\|Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 262366, Warszawa, Mazowieckie, 04-730, Poland\|Clinical Research Investigator Group, LLC /ID# 262357, Bayamon, 00960, Puerto Rico\|Puerto Rico Health Institute /ID# 262358, Dorado, 00646, Puerto Rico\|Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 262226, Ferrol, A Coruna, 15405, Spain\|Hospital Sant Joan de Deu /ID# 262599, Esplugues de Llobregat, Barcelona, 08950, Spain\|Hospital Regional Universitario de Malaga /ID# 262228, Malaga, 29011, Spain\|Duplicate_Hospital Universitario Virgen del Rocio /ID# 262712, Sevilla, 41013, Spain\|Hospital Clinico Universitario Lozano Blesa /ID# 262227, Zaragoza, 50009, Spain\|National Taiwan University Hospital /ID# 261695, Taipei City, Taipei, 100, Taiwan\|Linkou Chang Gung Memorial Hospital /ID# 261696, Taoyuan City, 333, Taiwan\|Addenbrooke's Hospital /ID# 262707, Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom\|Sheffield Children's Hospital NHS Foundation Trust /ID# 261832, Sheffield, England, S10 2TH, United Kingdom\|Barts Health NHS Trust /ID# 262811, London, Greater London, E1 2ES, United Kingdom\|Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 262778, Norwich, Norfolk, NR4 7UY, United Kingdom\|Royal Hospital for Children and Young People /ID# 262388, Edinburgh, EH16 4TJ, United Kingdom Less <<
NCT04195698	Atopic Dermatitis	PHASE3	COMPLETED	2023-09-11	University of Arkansas for Med... More >>ical Sciences /ID# 221021, Little Rock, Arkansas, 72205, United States\|Duplicate_First OC Dermatology Research Inc /ID# 218619, Fountain Valley, California, 92708-3701, United States\|UCSF Fresno /ID# 218453, Fresno, California, 93701-2302, United States\|California Allergy and Asthma Medical Group /ID# 218635, Los Angeles, California, 90025-7014, United States\|Dermatology Research Associates /ID# 218637, Los Angeles, California, 90045, United States\|Dermatology Clinical Trials /ID# 218627, Newport Beach, California, 92660-7853, United States\|Duplicate_UC Davis Health /ID# 218582, Sacramento, California, 95816-3300, United States\|Ucsd /Id# 218629, San Diego, California, 92103, United States\|Clinical Science Institute /ID# 218632, Santa Monica, California, 90404-2102, United States\|Miami Dermatology and Laser Institute /ID# 218664, Miami, Florida, 33173-3570, United States\|Florida International Rsrch cr /ID# 218663, Miami, Florida, 33173, United States\|GCP Research /ID# 218665, Saint Petersburg, Florida, 33705, United States\|Clinical Research Trials of Florida, Inc. /ID# 218438, Tampa, Florida, 33607, United States\|Georgia Pollens Clinical Research Centers, Inc /ID# 218441, Albany, Georgia, 31707-1282, United States\|Medical Dermatology Associates of Chicago /ID# 218551, Chicago, Illinois, 60654-6903, United States\|Sneeze, Wheeze, & Itch Associates, LLC /ID# 218552, Normal, Illinois, 61761, United States\|Dawes Fretzin, LLC /ID# 218478, Indianapolis, Indiana, 46256, United States\|Beacon Clinical Research, LLC /ID# 218636, Quincy, Massachusetts, 02169, United States\|Duplicate_Michigan Center for Research Company /ID# 218577, Clarkston, Michigan, 48346, United States\|Henry Ford Medical Center - New Center One /ID# 218575, Detroit, Michigan, 48202-3046, United States\|Duplicate_Allergy, Asthma & Immunology Associates, PC /ID# 218548, Lincoln, Nebraska, 68505-2343, United States\|Skin Specialists, PC /ID# 218549, Omaha, Nebraska, 68144, United States\|University Hospitals Case Medical Center /ID# 218574, Cleveland, Ohio, 44106, United States\|Southside Dermatology /ID# 218477, Tulsa, Oklahoma, 74132, United States\|Oregon Medical Research Center /ID# 218440, Portland, Oregon, 97223, United States\|Oregon Medical Research Center /ID# 218578, Portland, Oregon, 97239, United States\|Duplicate_Medical University of South Carolina /ID# 221072, Charleston, South Carolina, 29425, United States\|Clinical Research Solutions, LLC /ID# 218447, Jackson, Tennessee, 38305-2163, United States\|Orion Clinical Research /ID# 218565, Austin, Texas, 78759-4100, United States\|Sante Clinical Research /ID# 218911, Kerrville, Texas, 78028-9640, United States\|Clinical Research Partners, LLC /ID# 218480, Richmond, Virginia, 23220-4459, United States\|Duplicate_Premier Clinical Research /ID# 218583, Spokane, Washington, 99202, United States\|West Virginia Research Inst /ID# 218479, South Charleston, West Virginia, 25309, United States\|Holdsworth House Medical Practice /ID# 218755, Darlinghurst, New South Wales, 2010, Australia\|The Skin Hospital /ID# 218753, Darlinghurst, New South Wales, 2010, Australia\|Veracity Clinical Research /ID# 218754, Woolloongabba, Queensland, 4102, Australia\|Sinclair Dermatology - Melbourne /ID# 218751, East Melbourne, Victoria, 3002, Australia\|Burswood Dermatology /ID# 218752, Victoria Park, Western Australia, 6100, Australia\|Kirk Barber Research, CA /ID# 218727, Calgary, Alberta, T2G 1B1, Canada\|Duplicate_Dermatology Research Institute Inc. /ID# 218728, Calgary, Alberta, T2J 7E1, Canada\|Dr. Chih-ho Hong Medical Inc. /ID# 218725, Surrey, British Columbia, V3R 6A7, Canada\|Enverus Medical Research /ID# 218726, Surrey, British Columbia, V3V 0C6, Canada\|Dr. Wei Jing Loo Medicine Prof /ID# 218722, London, Ontario, N6H 5L5, Canada\|Duplicate_Lynderm Research Inc. /ID# 218723, Markham, Ontario, L3P 1X3, Canada\|DermEdge Research Inc. /ID# 218721, Mississauga, Ontario, L4Y 4C5, Canada\|North York Research Inc /ID# 218729, Toronto, Ontario, M2N 3A6, Canada\|Duplicate_K. Papp Clinical Research /ID# 218730, Waterloo, Ontario, N2J 1C4, Canada\|Dre Angelique Gagne-Henley M.D. inc. /ID# 218724, Saint-Jerome, Quebec, J7Z 7E2, Canada\|DermaPlus - Poliklinika za dermatologiju i venerologiju /ID# 218377, Zagreb, Grad Zagreb, 10000, Croatia\|Klinicki bolnicki centar Zagreb /ID# 218375, Zagreb, Grad Zagreb, 10000, Croatia\|Naftalan - Specijalna bolnica za medicinsku rehabilitaciju /ID# 218376, Ivanic-Grad, Zagrebacka Zupanija, 10310, Croatia\|Fakultni nemocnice Hradec Kralove /ID# 214176, Hradec Kralove, 500 05, Czechia\|Nemocnice Jihlava, prispevkova organizace /ID# 214178, Jihlava, 586 01, Czechia\|Fakultni Nemocnice Ostrava /ID# 214177, Ostrava, 708 52, Czechia\|Duplicate_Duplicate_Fakultni Nemocnice v Motole /ID# 214179, Praha, 150 06, Czechia\|Keski-pohjanmaa Central Hospital /ID# 214630, Kokkola, Keski-Pohjanmaa, 67200, Finland\|Duplicate_Oulun yliopistollinen sairaala /ID# 214628, Oulu, Pohjois-Pohjanmaa, 90220, Finland\|Mikkeli Central Hospital /ID# 214629, Mikkeli, 50100, Finland\|AP-HM - Hopital de la Timone /ID# 218957, Marseille CEDEX 05, Bouches-du-Rhone, 13385, France\|Polyclinique Courlancy /ID# 218955, Reims, Marne, 51100, France\|CHU de Nantes, Hotel Dieu -HME /ID# 218959, Nantes, Pays-de-la-Loire, 44000, France\|H?pital Charles-Nicolle /ID# 218960, Rouen, 76000, France\|CHU Toulouse - Hopital Larrey /ID# 218958, Toulouse, 31400, France\|Dermatologische Mahlow /ID# 214225, Blankenfelde-Mahlow, Brandenburg, 15831, Germany\|Duplicate_Klinikum Darmstadt GmbH /ID# 214224, Darmstadt, Hessen, 64283, Germany\|Universitaetsklinikum Frankfurt /ID# 214223, Frankfurt am Main, Hessen, 60590, Germany\|Duplicate_Universitaetsklinikum Muenster /ID# 214222, Munster, Niedersachsen, 48149, Germany\|Medizinische Hochschule Hannover /ID# 214226, Hannover, 30625, Germany\|Duplicate_Klinikum rechts der Isar - Technische Universitaet Muenchen /ID# 214221, Munich, 81675, Germany\|Oroshazi Korhaz /ID# 214986, Oroshaza, Bekes, 5900, Hungary\|Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 214984, Kaposvár, Somogy, 7400, Hungary\|Uno Medical Trials Kft /ID# 214987, Budapest, 1135, Hungary\|St Vincent's University Hospital /ID# 213558, Elm Park, Dublin, D04 T6F4, Ireland\|Duplicate_HaEmek Medical Center /ID# 218520, Afula, HaDarom, 1834111, Israel\|The Chaim Sheba Medical Center /ID# 218522, Ramat Gan, Tel-Aviv, 5265601, Israel\|Rabin Medical Center /ID# 218521, Haifa, 4941492, Israel\|Istituto Clinico Humanitas /ID# 215727, Rozzano, Milano, 20089, Italy\|Fondazione PTV Policlinico Tor Vergata /ID# 214093, Rome, Roma, 00133, Italy\|Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 214095, Milan, 20122, Italy\|Azienda Ospedaliero-Universitaria di Modena /ID# 214096, Modena, 41124, Italy\|Hospital Sultan Ismail /ID# 218881, Johor Bahru, Johor, 81100, Malaysia\|Hospital Pakar Sultanah Fatimah /ID# 218877, Muar, Johor, 84000, Malaysia\|Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 218879, Kuala Lumpur, Selangor, 56000, Malaysia\|Hospital Putrajaya /ID# 218880, Putrajaya, Wilayah Persekutuan Putrajaya, 62250, Malaysia\|University Malaya Med Ctr /ID# 218882, Kuala Lumpur, 59100, Malaysia\|Hospital Pulau Pinang /ID# 218878, Penang, 10450, Malaysia\|Bravis Ziekenhuis /ID# 218772, Bergen op Zoom, Noord-Brabant, 4624 VT, Netherlands\|Duplicate_Erasmus Medisch Centrum /ID# 218770, Rotterdam, Zuid-Holland, 3015 GD, Netherlands\|Universitair Medisch Centrum Groningen /ID# 218775, Groningen, 9713 GZ, Netherlands\|Universitair Medisch Centrum Utrecht /ID# 218771, Utrecht, 3584 CX, Netherlands\|Optimal Clinical Trials Ltd /ID# 218688, Grafotn, Auckland, 1010, New Zealand\|Wellington Regional Hospital /ID# 218689, Newtown, Wellington, 6021, New Zealand\|Clinical Trials New Zealand /ID# 218690, Hamilton, 3204, New Zealand\|Duplicate_Universitetssykehuset N-Norge, Tromso /ID# 214634, Tromso, Troms, 9019, Norway\|Dermoklinika Centrum Medyczne s.c. /ID# 214300, Lodz, Lodzkie, 90-436, Poland\|Duplicate_Pratia MCM Krakow /ID# 214303, Krakow, Malopolskie, 30-727, Poland\|Klinika Ambroziak Sp. z o.o. /ID# 214301, Warszawa, Mazowieckie, 02-953, Poland\|Duplicate_Duplicate_Royalderm Agnieszka Nawrocka /ID# 214302, Warszawa, Mazowieckie, 02-962, Poland\|ClinicMed Daniluk, Nowak Sp.k. /ID# 214299, Bialystok, Podlaskie, 15-879, Poland\|National University Hospital /ID# 219093, Singapore, 119074, Singapore\|Duplicate_Hospital Universitario de Bellvitge /ID# 214257, L'Hospitalet de Llobregat, Barcelona, 08907, Spain\|Hospital Universitario Dr. Negrin /ID# 214256, Las Palmas de Gran Canaria, Las Palmas, 35019, Spain\|Hospital de Manises /ID# 214258, Manises, Valencia, 46940, Spain\|Complejo Hospitalario Universitario de Pontevedra /ID# 214255, Pontevedra, 36071, Spain\|Hospital Universitario Arnau Vilanova /ID# 214254, Valencia, 46015, Spain\|Hospital Universitario y Politecnico La Fe /ID# 214252, Valencia, 46026, Spain\|National Taiwan University Hospital /ID# 218917, Taipei City, Taipei, 100, Taiwan\|Chung Shan Medical University Hospital /ID# 218919, Taichung, 40201, Taiwan\|China Medical University Hospital /ID# 218409, Taichung, 40447, Taiwan\|Taipei Municipal Wan Fang Hospital /ID# 218918, Taipei, 116, Taiwan\|Kyiv City Clinical Skin and Venereal Hospital /ID# 218382, Kyiv, Kyivska Oblast, 04209, Ukraine\|ME "Rivne Regional Dermatology and Venereology Dispensary" of RRC /ID# 218385, Rivne, 33028, Ukraine\|Victoria Hospital /ID# 213564, Kirkcaldy, Fife, KY2 5AH, United Kingdom\|Duplicate_The Royal Free London NHS Foundation Trust /ID# 213560, London, London, City Of, NW3 2QG, United Kingdom\|NHS Greater Glasgow and Clyde /ID# 213561, Glasgow, Scotland, G12 0XH, United Kingdom\|University Hospitals Sussex NHS Foundation Trust /ID# 213562, Worthing, West Sussex, BN11 2DH, United Kingdom Less <<

CAS No. :	1310726-60-3
Formula :	C₁₇H₁₉F₃N₆O
M.W :	380.37
SMILES Code :	O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F
Synonyms :	ABT-494
MDL No. :	MFCD30502663
InChI Key :	WYQFJHHDOKWSHR-MNOVXSKESA-N
Pubchem ID :	58557659

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302
Precautionary Statements:	P280-P305+P351+P338

LMY1	1 μM	48 h	Upadacitinib induced apoptosis.	PMC7585144
ED40515(+)	1 μM	48 h	Upadacitinib induced apoptosis.	PMC7585144
Murine YUMM1.7 melanoma cells	1 µM	72 h	Inhibited IFN-α-induced PD-1 expression	PMC11347607
Human A2058 melanoma cells	1 µM	72 h	Inhibited IFN-α-induced PD-1 expression	PMC11347607
Peripheral blood mononuclear cells	10-100 nM	7 days	Upadacitinib treatment restored the balance of peripheral blood monocyte subsets in RA patients and skewed macrophages towards the acquisition of an anti-inflammatory transcriptional and functional profile.	PMC10963568
BV2 cells	100 μM	24 h	Inhibited the JAK1-STAT6 signaling pathway, regulated microglia/macrophage polarization from the M1 to the M2 type, and inhibited their phagocytosis and migration	PMC10360098
T cells	0.0625 μM	4 days	To investigate the effect of Upadacitinib on Foxo1 expression in T cells, results showed that Upadacitinib significantly inhibited the down-regulation of Foxo1.	PMC10897180

NSG mice	ED40515(+)/IL-2 transgenic tumor model	Oral or osmotic pump	6 mg/kg	Daily for two weeks	Upadacitinib suppressed tumor growth more effectively via infusion pump than by the oral route. Single agents of Upadacitinib or AZD8055 delayed tumor growth, while combination therapy significantly reduced tumor volumes.	PMC7585144
Mice	YUMM1.7 melanoma model	Oral	180 mg/kg	Single daily dose for the duration of the experiment	Inhibited JAK1 signaling, reversing the efficacy of PD-1 checkpoint blockade	PMC11347607
Mice	HDM-induced model of Th2-driven allergic airway inflammation	Oral	20 mg/kg	Administered on Days 1-2 or Days 3-4 post-sensitization	The JAK1 inhibitor Upadacitinib, in the absence of IL-6 signaling, blocks IL-2 signaling and inhibits Th2 cell differentiation. When administered on Days 1-2, Upadacitinib effectively suppressed IL-2-driven STAT5 activation and Th2 cell polarization.	PMC10229632

Bio Calculators
Preparing Stock Solutions		1mg	5mg	10mg
Preparing Stock Solutions	1 mM 5 mM 10 mM	2.63mL 0.53mL 0.26mL	13.15mL 2.63mL 1.31mL	26.29mL 5.26mL 2.63mL
Dissolving Methods	Animal experiment Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn: in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Protocol 1 Protocol 2

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CAS No.: 1310726-60-3

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CAS No.: 1310726-60-3

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Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed