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Chemical Structure| 4506-66-5 Chemical Structure| 4506-66-5

Structure of Y15
CAS No.: 4506-66-5

Chemical Structure| 4506-66-5

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Y15 is a small molecule FAK phosphorylation inhibitor which specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK.

4.5 *For Research Use Only !

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Product Citations

Product Citations

Tran, Duyen K ; West, Sarah M ; Stewart, Anna E ; Kaminsky, Werner ; Jenekhe, Samson A ;

Abstract: N-type conjugated ladder polymers without side chains, such as BBL, have been shown to exhibit record-high mixed ionic-electronic transport properties, which have enabled diverse device applications. This study reports herein the design and synthesis of a series of dicyano-functionalized n-type conjugated ladder copolymers, BBL-x2CN, as new organic mixed ionic-electronic conductors (OMIECs). By combining the cyanation and random copolymerization design motifs, this study demonstrates that the electronic band structure (LUMO/HOMO energy levels) can be effectively tuned as a function of the copolymer composition of the dicyano functional group without compromising the unique planar polymer backbone intrinsic to BBL-type ladder polymers. Optimal mixed ionic-electronic transport properties probed via organic electrochemical transistors (OECTs) are found in BBL-202CN (20 mol%) devices that feature a high transconductance (≈3 mS), a good µC* value (≈2.8 FV−1cm−1s−1), and a fast transient response (τonoff = 40 ms/12 ms), which are substantially enhanced compared to those of the parent BBL of comparable molecular weight. The better OECT device performance found in BBL-202CN copolymer, compared to other copolymers, can be explained by a combination of improved crystallinity, delocalization length, and suppressed conformational disorder. These results provide new structure-property relationships with implications for the molecular engineering of high-performance n-type OMIECs.

Keywords: onjugated ladder polymers ; cyanation ; n-type conjugated polymers ; organic electrochemical transistors ; organic mixed ionic-electronic conductors ; random copolymers

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Product Details of Y15

CAS No. :4506-66-5
Formula : C6H14Cl4N4
M.W : 284.01
SMILES Code : NC1=CC(N)=C(N)C=C1N.[H]Cl.[H]Cl.[H]Cl.[H]Cl
MDL No. :MFCD00012970
InChI Key :BZDGCIJWPWHAOF-UHFFFAOYSA-N
Pubchem ID :78260

Safety of Y15

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Y15

RTK
cytoskeleton

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.52mL

0.70mL

0.35mL

17.61mL

3.52mL

1.76mL

35.21mL

7.04mL

3.52mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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