Home Chemistry Heterocyclic Building Blocks Pyridines Pyridin-4-Ylboronic Acid
Suzuki-Miyaura Coupling: Pyridin-4-ylboronic acid can react with aryl or vinyl halides in the presence of a palladium catalyst and a base to form biaryl or bivinyl compounds.
Heteroarylation: It can undergo heteroarylation reactions with various electrophiles, introducing the pyridine moiety into other organic molecules.
Cross-Coupling Reactions: Boronic acids can participate in cross-coupling reactions with various electrophiles, such as halides or pseudohalides, under appropriate catalytic conditions.
Reductive Amination: Pyridin-4-ylboronic acid can react with carbonyl compounds and an amine source in the presence of a reducing agent to form secondary or tertiary amines.
Oxidative Addition: Boronic acids can undergo oxidative addition reactions with transition metal complexes, leading to the formation of organometallic species.
Nucleophilic Addition: Boronic acids can undergo nucleophilic addition reactions with electrophiles, such as aldehydes or ketones, forming boronate esters.
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(5-Fluoro-2-isopropoxypyridin-4-yl)boronic acid
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(2-Ethoxy-5-fluoropyridin-4-yl)boronic acid
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(2-Butoxy-3-chloropyridin-4-yl)boronic acid
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(3-Chloro-2-isobutoxypyridin-4-yl)boronic acid
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(2-Methylpyridin-4-yl)boronic acid hydrochloride
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(2-Methoxypyridin-4-yl)boronic acid hydrochloride
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(5-Bromo-2-ethoxypyridin-4-yl)boronic acid
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5-Bromo-2-trifluoromethylpyridine-4-boronic acid
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