Home Chemistry Heterocyclic Building Blocks Pyridines 3-Methyl-5-Nitropyridine
Nitration: Since it already has a nitro group, further nitration might occur under harsh conditions, leading to the introduction of another nitro group.
Reduction: The nitro group can be reduced to an amine group (-NH2) under reducing conditions. This can be achieved using various reducing agents like iron and hydrochloric acid (Fe/HCl), tin and hydrochloric acid (Sn/HCl), or hydrogen gas over a metal catalyst.
Substitution Reactions: The methyl group can undergo substitution reactions. For instance, it can be replaced by another functional group in the presence of appropriate reagents and conditions.
Alkylation: The pyridine ring can undergo alkylation reactions, where alkyl groups can be introduced onto the ring. This can be achieved through Friedel-Crafts alkylation or other methods.
Oxidation: The methyl group or the nitrogen atom in the pyridine ring can undergo oxidation under appropriate conditions, leading to the formation of various oxidation products.
Condensation Reactions: The molecule can participate in condensation reactions with suitable reagents, forming new carbon-carbon or carbon-heteroatom bonds.
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