Home Chemistry Heterocyclic Building Blocks Piperidines Piperidin-3-Ol
Oxidation: The alcohol group can be oxidized to form the corresponding aldehyde or carboxylic acid under appropriate conditions.
Esterification: The hydroxyl group can react with carboxylic acids or acid derivatives to form esters through esterification reactions.
Ether Formation: The alcohol group can undergo nucleophilic substitution reactions with alky halides or sulfonates to form ethers.
Nucleophilic Substitution: The alcohol group can undergo nucleophilic substitution reactions with various electrophiles, leading to the formation of ether, ester, or other functionalized derivatives.
Reduction: The alcohol group can be reduced to the corresponding alkane using reducing agents such as lithium aluminum hydride or sodium borohydride.
Protection Reactions: The alcohol group can be protected using protecting groups such as tert-butyldimethylsilyl (TBDMS) or tert-butyldiphenylsilyl (TBDPS) groups.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Acid-Catalyzed Reactions: The alcohol group can undergo various acid-catalyzed reactions, such as dehydration to form alkenes or rearrangement reactions.
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tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
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tert-Butyl (3R,4S)-4-fluoro-3-hydroxypiperidine-1-carboxylate
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trans-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
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tert-Butyl ((3R,4S)-3-hydroxypiperidin-4-yl)carbamate
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tert-Butyl ((3S,4S)-3-hydroxypiperidin-4-yl)carbamate
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tert-Butyl 3-hydroxypiperidine-1-carboxylate
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(3S,4R)-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
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