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Chemical Structure| 56613-80-0 Chemical Structure| 56613-80-0
Chemical Structure| 56613-80-0

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Synonyms: (R)-(-)-2-Phenylglycinol

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Product Details of (-)-Phenylglycinol

CAS No. :56613-80-0
Formula : C8H11NO
M.W : 137.18
SMILES Code : N[C@H](C1=CC=CC=C1)CO
Synonyms :
(R)-(-)-2-Phenylglycinol
MDL No. :MFCD00008062
InChI Key :IJXJGQCXFSSHNL-QMMMGPOBSA-N
Pubchem ID :2724025

Safety of (-)-Phenylglycinol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of (-)-Phenylglycinol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56613-80-0 ]

[ 56613-80-0 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 7677-24-9 ]
  • [ 56613-80-0 ]
  • [ 2840-44-0 ]
  • (S)-7-Fluoro-1-((R)-1-phenyl-2-trimethylsilanyloxy-ethylamino)-1,2,3,4-tetrahydro-naphthalene-1-carbonitrile [ No CAS ]
  • (R)-7-Fluoro-1-((R)-1-phenyl-2-trimethylsilanyloxy-ethylamino)-1,2,3,4-tetrahydro-naphthalene-1-carbonitrile [ No CAS ]
  • 2
  • [ 56613-80-0 ]
  • [ 2840-44-0 ]
  • C18H18FNO [ No CAS ]
  • 2-(7-fluoro-3,4-dihydro-2<i>H</i>-naphthalen-1-ylideneamino)-2-phenyl-ethanol [ No CAS ]
  • 3
  • [ 56613-80-0 ]
  • [ 127842-54-0 ]
  • (R)-2-[1-(3,4-Bis-difluoromethoxy-phenyl)-meth-(E)-ylidene]-amino}-2-phenyl-ethanol [ No CAS ]
  • 4
  • [ 56613-80-0 ]
  • [ 2840-44-0 ]
  • C18H18FNO [ No CAS ]
  • 2-(7-fluoro-3,4-dihydro-2<i>H</i>-naphthalen-1-ylideneamino)-2-phenyl-ethanol [ No CAS ]
  • 5
  • [ 56613-80-0 ]
  • [ 2840-44-0 ]
  • N-[(R)-2'-hydroxy-1'-phenylethyl]-(S)-1-amino-8-fluoro-1,2,3,4-tetrahydronaphthalene [ No CAS ]
  • 6
  • [ 56613-80-0 ]
  • [ 135865-78-0 ]
  • 7
  • [ 56613-80-0 ]
  • [ 130-85-8 ]
  • [ 1313514-66-7 ]
  • 8
  • [ 23020-15-7 ]
  • [ 56613-80-0 ]
  • [ 928055-00-9 ]
  • 9
  • [ 56613-80-0 ]
  • [ 56844-12-3 ]
  • [ 1580542-43-3 ]
  • 10
  • [ 56613-80-0 ]
  • [ 56844-12-3 ]
  • [ 1580542-02-4 ]
YieldReaction ConditionsOperation in experiment
82% In butan-1-ol; at 145℃; for 24h; General procedure: Compound 1 (1.00 g, 4.01 mmol) was mixed with the benzylamine (12.03 mmol) and 1-butanol (3.5 mL) and agitated at 145 C for 18-24 h. Then the mixture was cooled to rt, diluted with water (50 mL) and diethyl ether (150 mL) or EtOAc (150 mL). After phase separation, the water phase was extracted with more diethyl ether (2 × 50 mL) or EtOAc (2 × 50 mL). The combined organic phases were washed with saturated aq NaCl solution (50 mL), dried over anhydrous Na2SO4, filtered and concentrated in vacuo, before the crude oil was dried under reduced pressure to constant weight to remove excess benzylamine. The compounds were purified by silica-gel column chromatography or crystallized as specified for each individual compound
  • 11
  • [ 745784-04-7 ]
  • [ 56613-80-0 ]
  • (+)-(R)-3,5-difluoro-N-(2-hydroxy-1-phenylethyl)picolinamide [ No CAS ]
  • 12
  • [ 745784-04-7 ]
  • [ 56613-80-0 ]
  • (+)-(R)-2-(3,5-difluoropyridin-2-yl)-4-phenyl-4,5-dihydrooxazole [ No CAS ]
 

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