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Chemical Structure| 93-56-1 Chemical Structure| 93-56-1
Chemical Structure| 93-56-1

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Synonyms: Styrene Glycol

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Product Details of 1-Phenylethane-1,2-diol

CAS No. :93-56-1
Formula : C8H10O2
M.W : 138.16
SMILES Code : OC(C1=CC=CC=C1)CO
Synonyms :
Styrene Glycol
MDL No. :MFCD00003546
InChI Key :PWMWNFMRSKOCEY-UHFFFAOYSA-N
Pubchem ID :7149

Safety of 1-Phenylethane-1,2-diol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of 1-Phenylethane-1,2-diol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93-56-1 ]

[ 93-56-1 ] Synthesis Path-Downstream   1~13

  • 1
  • [ 93-56-1 ]
  • [ 16355-00-3 ]
YieldReaction ConditionsOperation in experiment
With ketoreductase; stereospecific carbonyl reductase 1; zinc(II) sulfate; In aq. phosphate buffer; at 30℃; for 8h;pH 7.0;Enzymatic reaction; The biocatalytic deracemization of racemic (R,S)-PED was performed by the following methods: a reaction mixture (2.0 mL) containing 1gL-1 (R,S)-PED, 1 mM ZnSO4, and the purified enzymes of SCR1 and KRD. The reaction was performed at 30C and 200 rpm for 8 h. The analytical methods were carried out as described above. The reaction parameters, including activity ratio of SCR1 (20-100 U) to KRD (20-100 U), molar ratio of NADP+ (0.05-0.2 mM) to NADPH (0.05-0.2 mM), and substrate concentration (1-5 gL-1), were evaluated for the deracemization of (R,S)-PED to (R)-enantiomer.
  • 2
  • [ 186581-53-3 ]
  • [ 93-56-1 ]
  • [ 2979-22-8 ]
  • [ 3587-84-6 ]
  • 3
  • [ 93-56-1 ]
  • [ 2979-22-8 ]
  • [ 122-78-1 ]
  • [ 3587-84-6 ]
  • 4
  • [ 93-56-1 ]
  • [ 16355-00-3 ]
  • [ 25779-13-9 ]
YieldReaction ConditionsOperation in experiment
In hexane; isopropyl alcohol; at 35℃;Resolution of racemate;Product distribution / selectivity; 1HNMR (400 MHz, CD3COCD3) δ 3.53 (dd, J=2 Hz, 4 Hz, 1H, CHHOH), 3.64 (dd, J=2 Hz, 10 Hz, 1H, CHHOH), 4.04 (br, H, OH), 4.43 (br, 1H, OH), 4.73 (dd, J=4 Hz, 10 Hz, 1H, CHOH), 7.21-7.40 (m, 5H, aromatic H); HPLC (CHIRALCEL OB; solvent, hexane/2-propanol=98/2; flow rate, 1.0 ml/min; temperature, 35 C.; UV wavelength, 220 nm); tR of both optical isomers of 1-phenyl-1,2-ethanediol, 26.0 minutes and 36.2 minutes. In the reaction, the optical isomer detected at 26.0 minutes was a main component, but R and S isomers were not identified.
  • 5
  • [ 93-56-1 ]
  • [ 98-88-4 ]
  • [ 16355-00-3 ]
  • [ 25779-13-9 ]
  • [ 289625-33-8 ]
  • [ 70111-04-5 ]
  • 6
  • [ 67-56-1 ]
  • [ 93-56-1 ]
  • [ 2979-22-8 ]
  • 7
  • [ 51792-34-8 ]
  • [ 93-56-1 ]
  • [ 188647-04-3 ]
  • 8
  • [ 292638-84-7 ]
  • [ 67-56-1 ]
  • [ 93-56-1 ]
  • [ 2979-22-8 ]
  • [ 100-52-7 ]
  • 9
  • [ 93-56-1 ]
  • [ 7149-75-9 ]
  • C15H12ClN [ No CAS ]
  • 5-chloro-4-methyl-2-phenylindole [ No CAS ]
  • 10
  • [ 93-56-1 ]
  • [ 32202-61-2 ]
  • C17H15N [ No CAS ]
  • 12
  • [ 93-56-1 ]
  • [ 2979-22-8 ]
  • [ 122-78-1 ]
 

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