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Chemical Structure| 1006619-83-5 Chemical Structure| 1006619-83-5

Structure of 1006619-83-5

Chemical Structure| 1006619-83-5

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Product Details of [ 1006619-83-5 ]

CAS No. :1006619-83-5
Formula : C8H9ClN2O
M.W : 184.62
SMILES Code : O=C(N)C1=CC(Cl)=CC(C)=C1N
MDL No. :MFCD11044518
InChI Key :GJPVEWHLNAWLNW-UHFFFAOYSA-N
Pubchem ID :44887012

Safety of [ 1006619-83-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H317-H319
Precautionary Statements:P261-P264-P270-P272-P280-P301+P312+P330-P302+P352-P305+P351+P338-P333+P313-P337+P313-P363-P501

Application In Synthesis of [ 1006619-83-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1006619-83-5 ]

[ 1006619-83-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1006619-83-5 ]
  • [ 35344-95-7 ]
  • 6-chloro-8-methyl-2-(1H-pyrazol-4-yl)-2,3-dihydroquinazolin-4(1H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
50% In methanol; at 20℃; General procedure: Cyanuric chloride (28mg, 0.15mmol) was added to a mixture of 3a, 3b, 3k or 3s (1mmol) and 4b-4h (1.2mmol) in MeOH or DMSO (3mL). The mixture was stirred at room temperature for 0.5?2h. After completion, the mixture was extracted with EtOAc three times. The combined organic layers were washed with brine, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography eluting with CH2Cl2/MeOH (30/1) to afford D1-D12.
 

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