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Chemical Structure| 101084-51-9 Chemical Structure| 101084-51-9

Structure of 101084-51-9

Chemical Structure| 101084-51-9

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Product Details of [ 101084-51-9 ]

CAS No. :101084-51-9
Formula : C8H6N2OS
M.W : 178.21
SMILES Code : O=C(C1=CC=C2N=CSC2=C1)N
MDL No. :MFCD11643189

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Application In Synthesis of [ 101084-51-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 101084-51-9 ]

[ 101084-51-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 101084-51-9 ]
  • [ 58249-61-9 ]
YieldReaction ConditionsOperation in experiment
With trichlorophosphate; for 4h;Heating / reflux; A solution of 1,3-benzothiazole-6-carboxamide (1.96 g) in POCl3 (10 ml) was refluxed for 4 hours. The reaction solution was concentrated, and water was slowly added thereto at 0C. It was extracted with EtOAc, and the organic layer was dried over anhydrous MgSO4, and then filtered, and the filtrate was concentrated. The residue was purified by silica gel column chromatography (n-hexane:EtOAc=80:20 to 60:40) to obtain 1,3-benzothiazole-6-carbonitrile as a pale yellow solid.
 

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