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Chemical Structure| 101251-12-1 Chemical Structure| 101251-12-1

Structure of 101251-12-1

Chemical Structure| 101251-12-1

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Product Details of [ 101251-12-1 ]

CAS No. :101251-12-1
Formula : C8H10BrNO
M.W : 216.08
SMILES Code : NC1=CC=C(OCC)C(Br)=C1
MDL No. :MFCD09955449

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Application In Synthesis of [ 101251-12-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 101251-12-1 ]

[ 101251-12-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 846023-24-3 ]
  • [ 101251-12-1 ]
  • [ 122-51-0 ]
  • [ 846023-36-7 ]
YieldReaction ConditionsOperation in experiment
In isopropyl alcohol;Heating / reflux; EXAMPLE 18 3-Bromo-4-ethoxyanilino-N-(2,4-dichloro-5-methoxyphenyl)-2-cyano-2-propenamide To a suspension of <strong>[846023-24-3]2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide</strong> (715 mg, 2.74 mmol) in 50 mL of iso-propanol was added 3-bromo-4-ethoxyaniline (586 mg, 2.71 mmol). This mixture was heated to reflux and triethylorthoformate (2.7 mL, 16.2 mmol) was added dropwise. The reaction mixture was heated at reflux overnight. The mixture was filtered while still warm and the collected white solid was washed with iso-propanol to give 666 mg of 3-bromo-4-ethoxyanilino-N-(2,4-dichloro-5-methoxyphenyl)-2-cyano-2-propenamide, mp >250 C.; MS (ES) m/z 482.0, 484.0, 486.0 (M-H)- Analysis for C19H16BrCl2N3O3; Calcd: C, 47.04; H, 3.32; N, 8.66. Found: C, 46.64; H, 3.40; N, 8.59.
 

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