630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Asymmetric Synthesis >>Chiral Building BlocksChiral Catalysts, Chiral Ligands and Chiral ReagentsChiral Resolution ReagentsCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Crown LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsDiketone LigandsHydrogenationChemical Biology >>Conjugation ChemistryGlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylation
Peptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>Acridinium SeriesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic reagentOrganic Building Blocks >>Acyl ChloridesAlcoholsAldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic Hydrocarbons
AlkenylsAlkylsAlkynylsAmidesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic LiquidsSolid Supported SynthesisStains and Dyes >>
Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagents
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen sodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam besylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC LinkerADC Linker with PayloadADC ToxinAnti-infection >>3CLproAntibacterialAntifungalAntiparasiticAntiprotozoalAntiviralBVDVCMVDengue VirusApoptosis >>Apoptosis InducerBcl-2c-Mycc-RETC/EBPCARDCaspase
DAPKIAPAutophagy >>AutophagyLC3LRRK2LysosomemitoNEETPPTSPHKTFEBULKBiochemical Reagent >>Cationic & Neutral LipidsDendrimersDye ReagentCell Cycle >>APCAurora KinaseBUBCasein KinaseCdc25
CDKChkCRM1DHFRCytoskeleton >>ActinArp2/3 ComplexCytoplasmic dyneinDynaminFAKFilamin-AGap JunctionIntegrinMicrotubule/TubulinDNA Damage >>AP endonucleaseATAD5ATM/ATRBRCADNA Alkylator/CrosslinkerDNA-PKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes Organic Radicals Material Building Blocks >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents
Supramolecular Host Materials Nanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic ligands for MOF materials >>Carboxylic MOF ligandsHalogen seriesMOF ligands of nitrogenous carboxylic acids
Nitrogen containing MOF ligandsOrganic frame monomer blockOther MOF ligandsPorphyrin seriesTwo dimensional MOF ligandsOrganic monomer of COF >>Aldehyde based COF monomerAlkynyl COF monomerAmino COF monomerBoric acid COF monomerCyano COF monomerMultifunctional COF monomerOther COF monomerTriphene seriesOrganic Pigments >>Organic PigmentOther Materials >>Mateial OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Life Science
ADC-linkers >>ADC-linkerAmino Acids >>Amino AcidAmino Acid DerivativesAnalytical Science >>Stable IsotopesAPIs >>API
DNA/RNA >>Nucleosides and NucleotidesEnzymes >>EnzymeOther Life Science >>CRISPR/Cas9eIFIRE1Neuronal Signaling
Sigma ReceptorPeptides >>PeptideStandard Substrates >>Standard SubstrateSteroids >>Other Steroids
Contact Us
Home Cart 0 Sign in  
Chemistry
Heterocyclic Building Blocks
Thiazoles
Thiazole-4-carbohydrazide
Chemistry
Heterocyclic Building Blocks
Organic Building Blocks
Thiazoles
Amines Amides Hydrazines Hydrazides

[ CAS No. 101257-38-9 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 101257-38-9
Chemical Structure| 101257-38-9
Structure of 101257-38-9 * Storage: {[proInfo.prStorage]}

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 88K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 101257-38-9 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 101257-38-9 ]

SDS
Alternatived Products of [ 101257-38-9 ]
Alternatived Products of [ 101257-38-9 ]

Product Details of [ 101257-38-9 ]

CAS No. :101257-38-9 MDL No. :MFCD00614363
Formula : C4H5N3OS Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :143.17 g/mol Pubchem ID :-
Synonyms :

Safety of [ 101257-38-9 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P280-P305+P351+P338-P310 UN#:N/A
Hazard Statements:H302-H315-H319-H332-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 101257-38-9 ]

  • Downstream synthetic route of [ 101257-38-9 ]

[ 101257-38-9 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 14527-43-6 ]
  • [ 101257-38-9 ]
Reference： [1]Journal of medicinal and pharmaceutical chemistry,1959,vol. 1,p. 577,594
  • 2
  • [ 101257-38-9 ]
  • [ 98-09-9 ]
  • [ 99185-90-7 ]
YieldReaction ConditionsOperation in experiment
With pyridine; ethanol
Reference： [1]Campaigne et al. [Journal of medicinal and pharmaceutical chemistry, 1959, vol. 1, p. 577,594] Erne et al. [Helvetica Chimica Acta, 1951, vol. 34, p. 143,147]
  • 3
  • [ 101257-38-9 ]
  • [ 1225430-40-9 ]
  • C46H44ClN3O7S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water; N,N-dimethyl-formamide at 20℃; Inert atmosphere;
Reference： [1]Location in patent: experimental part Lee, Junwon; Lee, Sung-Han; Seo, Hee Jeong; Son, Eun-Jung; Lee, Suk Ho; Jung, Myung Eun; Lee, MinWoo; Han, Ho-Kyun; Kim, Jeongmin; Kang, Jahyo; Lee, Jinhwa [Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 6, p. 2178 - 2194]
  • 4
  • [ 1254073-60-3 ]
  • [ 101257-38-9 ]
YieldReaction ConditionsOperation in experiment
Stage #1: 1,1-dimethylethyl 2-(1,3-thiazol-4-ylcarbonyl)hydrazinecarboxylate With hydrogenchloride In 1,4-dioxane at 20℃; for 18h; Stage #2: With ammonia In dichloromethane 1 ,1-Dimethylethyl 2-(1 ,3-thiazol-4-ylcarbonyl)hydrazinecarboxylate (I64) (1.378 g, 5.66 mmol) was dissolved in 1 ,4-dioxane (15 ml.) and to this was added 4M HCI in 1 ,4-dioxane (14.16 ml_, 56.6 mmol). The solution was then stirred at room temperature for 18 hours. The solvent was then evaporated in vacuo and the remaining residue was loaded onto an SCX cartridge and washed with methanol before being eluted with 2M NH3 in DCM. The solution was then evaporated in vacuo to yield the product in 0.784 g. 1H NMR (400 MHz; CDCI3) δ 8.78 (1 H,d), 8.47 (1 H, broad s), 8.21 ( 1 H,d), 4.10 (2H, broad s).
Reference： [1]Current Patent Assignee: GLAXOSMITHKLINE PLC - WO2010/125102, 2010, A1 Location in patent: Page/Page column 94
  • 5
  • [ 141-30-0 ]
  • [ 101257-38-9 ]
  • [ 1340528-42-8 ]
YieldReaction ConditionsOperation in experiment
With triethylamine hydrochloride at 140℃;
Reference： [1]Franzini, Maurizio; Ye, Xiaocong M.; Adler, Marc; Aubele, Danielle L.; Garofalo, Albert W.; Gauby, Shawn; Goldbach, Erich; Probst, Gary D.; Quinn, Kevin P.; Santiago, Pam; Sham, Hing L.; Tam, Danny; Truong, Anh; Ren, Zhao [Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 7, p. 1967 - 1973]
  • 6
  • [ 101257-38-9 ]
  • (1-phenyl-propylidene)-<i>p</i>-tolyl-amine [ No CAS ]
  • 4-(5-phenyl-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thiazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
76% In butan-1-ol at 108℃; for 72h;
Reference： [1]Brooker, Sally; Singh, Sandhya [Inorganic Chemistry, 2020]

Tags: 101257-38-9 synthesis path| 101257-38-9 SDS| 101257-38-9 COA| 101257-38-9 purity| 101257-38-9 application| 101257-38-9 NMR| 101257-38-9 COA| 101257-38-9 structure

Related Products
Historical Records

Related Functional Groups of
[ 101257-38-9 ]

Hydrazines

Chemical Structure| 101767-28-6

[ 101767-28-6 ]

2-Methylthiazole-4-carbohydrazide

Similarity: 0.88

Chemical Structure| 100517-03-1

[ 100517-03-1 ]

5-Methylthiazole-4-carbohydrazide

Similarity: 0.82

Amines

Chemical Structure| 3575-09-5

[ 3575-09-5 ]

Thiazole-4-carboxamide

Similarity: 0.89

Chemical Structure| 101767-28-6

[ 101767-28-6 ]

2-Methylthiazole-4-carbohydrazide

Similarity: 0.88

Chemical Structure| 100517-03-1

[ 100517-03-1 ]

5-Methylthiazole-4-carbohydrazide

Similarity: 0.82

Hydrazides

Chemical Structure| 101767-28-6

[ 101767-28-6 ]

2-Methylthiazole-4-carbohydrazide

Similarity: 0.88

Chemical Structure| 100517-03-1

[ 100517-03-1 ]

5-Methylthiazole-4-carbohydrazide

Similarity: 0.82

Amides

Chemical Structure| 3575-09-5

[ 3575-09-5 ]

Thiazole-4-carboxamide

Similarity: 0.89

Chemical Structure| 101767-28-6

[ 101767-28-6 ]

2-Methylthiazole-4-carbohydrazide

Similarity: 0.88

Chemical Structure| 100517-03-1

[ 100517-03-1 ]

5-Methylthiazole-4-carbohydrazide

Similarity: 0.82

Related Parent Nucleus of
[ 101257-38-9 ]

Thiazoles

Chemical Structure| 3575-09-5

[ 3575-09-5 ]

Thiazole-4-carboxamide

Similarity: 0.89

Chemical Structure| 101767-28-6

[ 101767-28-6 ]

2-Methylthiazole-4-carbohydrazide

Similarity: 0.88

Chemical Structure| 100517-03-1

[ 100517-03-1 ]

5-Methylthiazole-4-carbohydrazide

Similarity: 0.82