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Chemical Structure| 1019918-88-7 Chemical Structure| 1019918-88-7

Structure of 1019918-88-7

Chemical Structure| 1019918-88-7

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Product Details of [ 1019918-88-7 ]

CAS No. :1019918-88-7
Formula : C12H7Cl2N3
M.W : 264.11
SMILES Code : ClC1=CC=CC=C1C2=NN=C3C=C(Cl)C=CN32

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Application In Synthesis of [ 1019918-88-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1019918-88-7 ]

[ 1019918-88-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 170230-88-3 ]
  • [ 1019918-88-7 ]
  • [ 1019918-49-0 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 80℃; for 8h; Step 2: Synthesis of 3-(3-(2-Chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-4-methylbenzoic acid A mixture of 7-chloro-3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridine (1.77 g, 6.7 mmol), <strong>[170230-88-3]3-borono-4-methylbenzoic acid</strong> (1.57 g, 8.7 mmol), Pd(PPh3)2Cl2 (0.329 g, 0.46 mmol, Strem), and sodium carbonate (2.13 g, 20 mmol, JT Baker) in DME:EtOH:H2O=7:2:3 (8 ml) was heated to 80 C. for 8 h. The mixture was cooled to room temperature, diluted with MeOH and filtered through Celite. The filtrate was concentrated to yield the title compound as a brown solid. MS (ESI, pos. ion) m/z: 364.0 (M+1).
 

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