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Chemical Structure| 1024-41-5 Chemical Structure| 1024-41-5

Structure of 1024-41-5

Chemical Structure| 1024-41-5

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Product Details of [ 1024-41-5 ]

CAS No. :1024-41-5
Formula : C14H14O3S
M.W : 262.32
SMILES Code : O=S(C1=CC=C(C)C=C1)(OCC2=CC=CC=C2)=O
MDL No. :MFCD01318299
InChI Key :OVHDZBAFUMEXCX-UHFFFAOYSA-N
Pubchem ID :160558

Safety of [ 1024-41-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 1024-41-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1024-41-5 ]

[ 1024-41-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 870774-25-7 ]
  • [ 1024-41-5 ]
  • [ 611-45-0 ]
  • 2
  • [ 516-09-6 ]
  • [ 1024-41-5 ]
  • 4-benzyloxy-3-methylfuran-2(5H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
86% With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 24h;Inert atmosphere; Under N2 atmosphere, DMF (1.8 mL) was added to a mixture of 6 (101 mg, 0.88 mmol), 9 (345 mg, 1.31mmol), prepared in solvent-free condition, and K2CO3 (365 mg, 2.64 mmol) at rt and the reaction mixturewas stirred at rt for 24 h. H2O (1.0 mL) was added and the whole was extracted with AcOEt (3 x 10mL). The combined organic layer was washed with saturated aqueous NH4Cl, H2O, saturated aqueousNaHCO3, and brine (each 1 x 1 mL), and dried over Na2SO4. The solvent was evaporated in vacuo togive a yellow oil, which was purified by column chromatography (CC) (SiO2, hexane - AcOEt 4 : 1) togive 7 as pale yellow solids (154 mg, 86%).mp 111-112 C (from hexane - AcOEt = 1 : 1). IR max (cm-1) 1727, 1650. 1H-NMR (ppm) 1.86 (3H,t, J = 1.5 Hz, CH3), 4.63 (2H, q, J = 1.5 Hz, CH2), 5.22 (2H, s, CH2), 7.34-7.45 (5H, m, Ar-H).13C-NMR (ppm) 7.4, 66.0, 72.3, 99.6, 127.3, 129.0, 135.0, 171.2, 175.2 (one C missing). HR-EIMSm/z 204.0773 (Calcd for C12H12O3: 204.0787).
  • 3
  • [ 516-09-6 ]
  • [ 1024-41-5 ]
  • 4-benzyloxy-3-methylfuran-2(5H)-one [ No CAS ]
  • 3-benzyl-3-methylfuran-2,4-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With cesium fluoride; In N,N-dimethyl-formamide; at 20℃;Inert atmosphere; General procedure: Under N2 atmosphere, DMF (1.8 mL) was added to a mixture of 6 (101 mg, 0.88 mmol), 9 (345 mg, 1.31mmol), prepared in solvent-free condition, and K2CO3 (365 mg, 2.64 mmol) at rt and the reaction mixturewas stirred at rt for 24 h. H2O (1.0 mL) was added and the whole was extracted with AcOEt (3 x 10mL). The combined organic layer was washed with saturated aqueous NH4Cl, H2O, saturated aqueousNaHCO3, and brine (each 1 x 1 mL), and dried over Na2SO4. The solvent was evaporated in vacuo togive a yellow oil, which was purified by column chromatography (CC) (SiO2, hexane - AcOEt 4 : 1) togive 7 as pale yellow solids (154 mg, 86%).mp 111-112 C (from hexane - AcOEt = 1 : 1). IR max (cm-1) 1727, 1650. 1H-NMR (ppm) 1.86 (3H,t, J = 1.5 Hz, CH3), 4.63 (2H, q, J = 1.5 Hz, CH2), 5.22 (2H, s, CH2), 7.34-7.45 (5H, m, Ar-H).13C-NMR (ppm) 7.4, 66.0, 72.3, 99.6, 127.3, 129.0, 135.0, 171.2, 175.2 (one C missing). HR-EIMSm/z 204.0773 (Calcd for C12H12O3: 204.0787).
 

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