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Chemical Structure| 10517-64-3 Chemical Structure| 10517-64-3

Structure of 10517-64-3

Chemical Structure| 10517-64-3

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Product Details of [ 10517-64-3 ]

CAS No. :10517-64-3
Formula : C15H11NO
M.W : 221.25
SMILES Code : O=C(C1=CC=CC=C1)CC2=CC=CC=C2C#N
MDL No. :MFCD00029561

Safety of [ 10517-64-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 10517-64-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10517-64-3 ]

[ 10517-64-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 178686-24-3 ]
  • [ 10517-64-3 ]
  • [ 57-13-6 ]
  • [ 1283117-84-9 ]
YieldReaction ConditionsOperation in experiment
29% With hydrogenchloride; In ethanol; water;Reflux; [00217] A mixture of 2-(2-oxo-2-phenylethyl)benzonitrile (Intermediate 33) (100 mg,0.45 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (87 mg, 0.41 mmol), urea (81 mg, 1.36 mmol), and concentrated HC1 solution (0.03 mL, 0.41 mmol) in EtOH (5 mL) was refluxed overnight. The mixture was concentrated, and purified by preparative HPLC to give Compound 70 (54.26 mg, yield 29%) as a yellow solid. 1H NMR (DMSO- 6 300 MHz): (510.24 (s, 1H), 8.91 (s, 1H), 7.61(s, 1H), 7.51-7.44 (m, 2H), 7.31 (s, 1H), 7.24-7.16 (m, 4H), 7.13-7.08 (m, 3H), 5.37 (s, 1H), 3.99-3.93 (m, 2H), 1.31 (t, J = 6.8 Hz, 3H); MS (ESI): m/z 456.8 [M+l]+.
 

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