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Chemical Structure| 105836-68-8 Chemical Structure| 105836-68-8

Structure of 105836-68-8

Chemical Structure| 105836-68-8

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Product Details of [ 105836-68-8 ]

CAS No. :105836-68-8
Formula : C12H9Cl2N
M.W : 238.11
SMILES Code : ClC1=CC(Cl)=CC(NC2=CC=CC=C2)=C1

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Application In Synthesis of [ 105836-68-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 105836-68-8 ]

[ 105836-68-8 ] Synthesis Path-Downstream   1~1

  • 1
  • ammonium thiocyanate [ No CAS ]
  • [ 105836-68-8 ]
  • [ 98-88-4 ]
  • [ 107707-33-5 ]
YieldReaction ConditionsOperation in experiment
238 g (88%) With sodium hydroxide; In water; acetone; A. Preparation of N-[3,5-Dichlorophenyl]thiourea and Related Compounds of Formula 2 To a mixture of 4 liters of acetone and 110 g (1.5 moles) of ammonium thiocyanate are added dropwise 173 g (1.23 moles) of benzoyl chloride. The reaction mixture is then heated for a further 15 minutes. Next, 200 g (1.23 moles) of 3,5-dichlorophenyl aniline dissolved in 200 ml of acetone are added. The mixture is then heated for a further 30 minutes, cooled and poured into 4 liters of water. The precipitate is collected and rinsed with 1 liter of water. The crystals are mixed with 2 liters of water containing 50 g of sodium hydroxide. The mixture is heated for 30 minutes and then cooled. The precipitate is collected to give 238 g (88%) of N-[3,5-dichlorophenyl]thiourea, m.p. 180 C.
 

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