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Chemical Structure| 1072-21-5 Chemical Structure| 1072-21-5

Structure of 1072-21-5

Chemical Structure| 1072-21-5

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Product Details of [ 1072-21-5 ]

CAS No. :1072-21-5
Formula : C6H10O2
M.W : 114.14
SMILES Code : O=CCCCCC=O
MDL No. :MFCD13186001

Safety of [ 1072-21-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302+H332-H314-H317-H334-H335-H400-H411
Precautionary Statements:P261-P264-P270-P271-P272-P273-P280-P284-P301+P312+P330-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P333+P313-P342+P311-P362+P364-P391-P403+P233-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 1072-21-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1072-21-5 ]

[ 1072-21-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 7724-12-1 ]
  • [ 1072-21-5 ]
  • (S)-2-(6-(azepan-1-yl)benzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid [ No CAS ]
  • 2
  • [ 7724-12-1 ]
  • [ 1072-21-5 ]
  • 6-(azepan-1-yl)benzo[d]thiazole-2-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
36% Adipaldehyde (65 mg, 0.57 mmol) was dissolved in 2 mL of glacial acetic acid,Followed by the addition of 2-cyano 6-aminobenzothiazole(50 mg, 0.285 mmol), undissolved,After stirring for 10 minutes, sodium cyanoborohydride (62 mg, 1 mmol) was added,There are a lot of bubbles produced,When the reaction solution showed a clear orange-red solution,To the reaction solution was added 20 mL of ethyl acetate,Stir for 5 minutes,Saturated sodium carbonate solution (3 x 3 mL) was added in duplicate,Until there is no bubble generation in the reaction solution,Extracted three times with ethyl acetate (3 x 50 mL)The ethyl acetate layer was washed successively with saturated sodium carbonate solution and sodium chloride solution,The ethyl acetate layer was dried over anhydrous sodium sulfate, filtered,The target was then purified on a silica gel column,Get 26mg6- (azepan-1-yl) benzo [d] thiazole-2-carbonitrile(1-1) yellow solid in 36percent yield
 

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