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Chemical Structure| 1095823-03-2 Chemical Structure| 1095823-03-2

Structure of 1095823-03-2

Chemical Structure| 1095823-03-2

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Product Details of [ 1095823-03-2 ]

CAS No. :1095823-03-2
Formula : C8H12N4O2
M.W : 196.21
SMILES Code : O=C(C1=NC=NC(NC)=C1N)OCC
MDL No. :MFCD20686653

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Application In Synthesis of [ 1095823-03-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1095823-03-2 ]

[ 1095823-03-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1095823-03-2 ]
  • [ 89531-58-8 ]
  • [ 1095823-09-8 ]
YieldReaction ConditionsOperation in experiment
20% Synthesis of Compound 22.1. A mixture of oxalyl chloride (87 uL, 1.0 mmol) was added to a mixture of <strong>[89531-58-8]2-morpholinoacetic acid hydrochloride</strong> (93 mg, 0.51 mmol), TEA (70 uL, 0.5 mmol), and DMF (1 drop) in acetonitrile (1 mL) was stirred. After 1 hr, the solvent was removed in vacuo. The acid chloride was redissolved in acetonitrile (1 mL) and added to a solution of compound 21.1 (80 mg, 0.4 mmol) in pyridine (300 uL, 4 mmol). The solvent was removed in vacuo. MS m/z 324 [M+1]+. A solution of residue in acetic acid (1 mL) was heated at 130° C. in a microwave for 10 min. The solvent was removed in vacuo to afford compound 22.1 (20 mg, 20percent) MS m/z 306 [M+1]+.
 

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