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Chemical Structure| 111252-31-4 Chemical Structure| 111252-31-4

Structure of 111252-31-4

Chemical Structure| 111252-31-4

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Product Details of [ 111252-31-4 ]

CAS No. :111252-31-4
Formula : C7H5BrO3
M.W : 217.02
SMILES Code : O=C(O)/C=C/C1=CC=C(Br)O1
MDL No. :MFCD02708232
InChI Key :IIMYTCICBUBFJH-DUXPYHPUSA-N
Pubchem ID :946089

Safety of [ 111252-31-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 111252-31-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 111252-31-4 ]

[ 111252-31-4 ] Synthesis Path-Downstream   1~16

  • 1
  • [ 1899-24-7 ]
  • [ 64-17-5 ]
  • [ 111252-31-4 ]
  • 3
  • [ 67-56-1 ]
  • [ 111252-31-4 ]
  • [ 62157-66-8 ]
  • 4
  • [ 111252-31-4 ]
  • [ 35115-89-0 ]
  • 6
  • [ 111252-31-4 ]
  • 2-(1-amino-ethyl)-5-methyl-thieno[2,3-<i>d</i>][1,3]oxazin-4-one; compound with trifluoro-acetic acid [ No CAS ]
  • 3-(5-bromo-furan-2-yl)-<i>N</i>-[1-(5-methyl-4-oxo-4<i>H</i>-thieno[2,3-<i>d</i>][1,3]oxazin-2-yl)-ethyl]-acrylamide [ No CAS ]
  • 7
  • α.β-dibromo-β-<5-bromo-furyl-(2)>-propionic acid [ No CAS ]
  • [ 111252-31-4 ]
  • 8
  • 3<i>t</i>-<4<i>r</i>,5<i>t</i>(?)-dibromo-4,5-dihydro-<2>furyl>-acrylic acid ethyl ester [ No CAS ]
  • [ 111252-31-4 ]
  • 10
  • [ 111252-31-4 ]
  • [ 69527-54-4 ]
  • 12
  • [ 111252-31-4 ]
  • [ 62157-66-8 ]
  • 14
  • [ 111252-31-4 ]
  • [ 50527-72-5 ]
  • 16
  • [ 1899-24-7 ]
  • [ 141-82-2 ]
  • [ 111252-31-4 ]
YieldReaction ConditionsOperation in experiment
60% With piperidine; In pyridine; for 3.0h;Inert atmosphere; Reflux; General Procedure: Piperidine was added to a solution of the appropriate aldehyde (4.97 mmol), malonic acid (5.96 mmol) and pyridine (10.94 mmol) under nitrogen atmosphere. The reaction mixture was heated to reflux under vigorous stirring for 3 hours, after which according to TLC the reaction was completed. The reaction mixture was allowed to cool and EtOAc (20 mL) was added, acidified to pH 5 with 1 M HCl, and the organic layer was sequentially washed with water, dried over MgSO4 and concentrated in vacuo. The pure desired product was obtained after purification by column chromatography.
 

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[ 111252-31-4 ]

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