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Chemical Structure| 1126-72-3 Chemical Structure| 1126-72-3

Structure of 1126-72-3

Chemical Structure| 1126-72-3

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Product Details of [ 1126-72-3 ]

CAS No. :1126-72-3
Formula : C8H6ClNO
M.W : 167.59
SMILES Code : ClC(/C=C/C1=CC=CN=C1)=O
MDL No. :MFCD04972007

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Application In Synthesis of [ 1126-72-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1126-72-3 ]

[ 1126-72-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1202759-91-8 ]
  • [ 1126-72-3 ]
  • C27H25FN6O3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
30% Weigh 185 mg of Al intermediate in a 50 ml round bottom flask, add 5 ml of DCM and 140 mul of triethylamine as solvent.After stirring at 0C for about 5 minutes, 101 mg of the A5 intermediate was added to the reaction system. After stirring at 0C for about 0.5 hour, 100 ml of a saturated aqueous solution of sodium hydrogencarbonate was added, followed by extraction with 15 ml of DCM 3 times, and the resulting organic phase was dried under reduced pressure. The solvent was applied and the residue was passed through a column of silica gel with DCM:MeOH = 70:1 (by volume) to give 75 mg of the compound represented by Formula III-4 in a 30% yield.
 

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