Home Cart 0 Sign in  

[ CAS No. 114772-38-2 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

type HazMat fee
Excepted Quantity Free
Inaccessible (Haz class 6.1), Domestic USD 41.00
Inaccessible (Haz class 6.1), International USD 64.00
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 83.00
Accessible (Haz class 3, 4, 5 or 8), International USD 133.00
Chemical Structure| 114772-38-2
Chemical Structure| 114772-38-2
Structure of 114772-38-2 * Storage: {[proInfo.prStorage]}

Quality Control of [ 114772-38-2 ]

Related Doc. of [ 114772-38-2 ]

SDS
Alternatived Products of [ 114772-38-2 ]
Alternatived Products of [ 114772-38-2 ]

Product Details of [ 114772-38-2 ]

CAS No. :114772-38-2 MDL No. :MFCD06200816
Formula : C15H13BrO2 Boiling Point : 412.8°C at 760 mmHg
Linear Structure Formula :- InChI Key :N/A
M.W :305.17 g/mol Pubchem ID :11012181
Synonyms :

Safety of [ 114772-38-2 ]

Signal Word:Danger Class:8
Precautionary Statements:P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501 UN#:3261
Hazard Statements:H302-H314 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 114772-38-2 ]

  • Upstream synthesis route of [ 114772-38-2 ]
  • Downstream synthetic route of [ 114772-38-2 ]

[ 114772-38-2 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 114772-38-2 ]
  • [ 152628-02-9 ]
  • [ 144701-48-4 ]
YieldReaction ConditionsOperation in experiment
88%
Stage #1: With potassium hydroxide In dimethyl sulfoxide at 25 - 50℃; for 4 h;
Stage #2: With water; acetic acid In water; dimethyl sulfoxide at 20℃;
Example I Preparation of 14'-12-n-propvl-4-methvl-6-(1-methvl benzimidazol-2-yl) benzimidazol-1-yl methyl] biphenyl-2-carboxylic acidl 50 gm of [1H - Benzimidazole-2-n-propyl-4-methyl-6-(1'methyl benzimidazole-2'- yl) ] was added to 200 ml dimethyl sulfoxide and 50 gm of potassium hydroxide. To this was added 60 gm of methyl-4- (bromomethyl) at ambient temperature. The contents were stirred for 2 hours at 25-30 C, then heated to 40-50 C and maintained for 2 hours. About 500 ml water was added to the reaction mixture at room temperature and acidified to pH 4 with acetic acid. The reaction mixture was filtered and washed with purified water, dried under reduced pressure at 50-60 C to give 80 gm (88 percent) of the title product.
80%
Stage #1: With sodium hydroxide In dimethyl sulfoxide at 25 - 50℃; for 4 h;
Stage #2: With water; acetic acid In water; dimethyl sulfoxide
Example 3 Preparation of f4' - [2-n-propyl-4-methyl-6-(1-methyl benzimidazol-2-vl) benzimidazol -1-vl methvll biphenvl-2-carboxvlic acidl 50 gm of [1 H - Benzimidazole-2-n - propyl-4-methyl-6-(1'-methyl benzimidazole-2'- yl) ] was added to 200 ml dimethyl sulfoxide and 50 gm of sodium hydroxide. To this was added 60 gm of methyl-4- (bromomethyl) biphenyl-2-carboxylate at ambient temperature. The contents were stirred for 2 hours at 25-30 C and then heated to 40-50 and maintained for 2 hours. About 500 ml water was added to the reaction mixture and acidified with acetic acid to pH 4.2, extract4ed twice with 250 ml of dichloromethane and the combined extracts were concentrated and isolated by filtration after addition of 300 ml acetone, dried under reduced pressure at 50-60 C to give 75.0 gm (80percent) of the title compound.
Reference: [1] Patent: WO2005/108375, 2005, A1, . Location in patent: Page/Page column 2-4,7,9-10
[2] Patent: WO2005/108375, 2005, A1, . Location in patent: Page/Page column 2-4,8-10
  • 2
  • [ 114772-38-2 ]
  • [ 144701-48-4 ]
Reference: [1] Organic Process Research and Development, 2007, vol. 11, # 1, p. 81 - 85
[2] Patent: JP2016/53009, 2016, A,
Historical Records

Related Functional Groups of
[ 114772-38-2 ]

Bromides

Chemical Structure| 25109-86-8

[ 25109-86-8 ]

Methyl 2-(2-bromoethyl)benzoate

Similarity: 0.90

Chemical Structure| 2417-73-4

[ 2417-73-4 ]

Methyl 2-bromomethylbenzoate

Similarity: 0.88

Chemical Structure| 1129-28-8

[ 1129-28-8 ]

Methyl 3-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 2417-72-3

[ 2417-72-3 ]

Methyl 4-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 16281-97-3

[ 16281-97-3 ]

Methyl 4-(1-bromoethyl)benzoate

Similarity: 0.87

Benzyl bromides

Chemical Structure| 2417-73-4

[ 2417-73-4 ]

Methyl 2-bromomethylbenzoate

Similarity: 0.88

Chemical Structure| 1129-28-8

[ 1129-28-8 ]

Methyl 3-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 2417-72-3

[ 2417-72-3 ]

Methyl 4-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 16281-97-3

[ 16281-97-3 ]

Methyl 4-(1-bromoethyl)benzoate

Similarity: 0.87

Chemical Structure| 114772-40-6

[ 114772-40-6 ]

2-Boc-4'-(Bromomethyl)biphenyl

Similarity: 0.86

Aryls

Chemical Structure| 25109-86-8

[ 25109-86-8 ]

Methyl 2-(2-bromoethyl)benzoate

Similarity: 0.90

Chemical Structure| 2417-73-4

[ 2417-73-4 ]

Methyl 2-bromomethylbenzoate

Similarity: 0.88

Chemical Structure| 1129-28-8

[ 1129-28-8 ]

Methyl 3-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 2417-72-3

[ 2417-72-3 ]

Methyl 4-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 16281-97-3

[ 16281-97-3 ]

Methyl 4-(1-bromoethyl)benzoate

Similarity: 0.87

Esters

Chemical Structure| 25109-86-8

[ 25109-86-8 ]

Methyl 2-(2-bromoethyl)benzoate

Similarity: 0.90

Chemical Structure| 2417-73-4

[ 2417-73-4 ]

Methyl 2-bromomethylbenzoate

Similarity: 0.88

Chemical Structure| 1129-28-8

[ 1129-28-8 ]

Methyl 3-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 2417-72-3

[ 2417-72-3 ]

Methyl 4-(bromomethyl)benzoate

Similarity: 0.88

Chemical Structure| 16281-97-3

[ 16281-97-3 ]

Methyl 4-(1-bromoethyl)benzoate

Similarity: 0.87