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Chemical Structure| 114878-60-3 Chemical Structure| 114878-60-3

Structure of 114878-60-3

Chemical Structure| 114878-60-3

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Product Details of [ 114878-60-3 ]

CAS No. :114878-60-3
Formula : C10H12ClN3O2
M.W : 241.67
SMILES Code : O=[N+](C1=CC=C(N2CCNCC2)C(Cl)=C1)[O-]
MDL No. :MFCD00640776
InChI Key :JNUWBYPJOBSXDN-UHFFFAOYSA-N
Pubchem ID :2771331

Safety of [ 114878-60-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 114878-60-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 114878-60-3 ]

[ 114878-60-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 16883-16-2 ]
  • [ 114878-60-3 ]
  • [ 341001-38-5 ]
YieldReaction ConditionsOperation in experiment
76% With pyridine; In 1,4-dioxane; at 0 - 20℃; A solution of 5-methyl-3-isoxazole-4-carbonyl chloride (1.19g, 5.37mmol) in dioxane (15ml, anhydrous) was added dropwise to a cooled mixture (0C) containing l-(2-chloro-4- nitrophenyl)-piperazine (1.3g, 5.37mmol) and pyridine (0.81ml, O.Olmol) in dioxane (25ml, anhydrous). The reaction solution was allowed to attain ambient temperature. Water was added to the solution affording an oily orange residue. The water was removed and the oily residue was dissolved in a mixture of MeOH/Acetonitrile (2: 1) which gave crystalline nucleozin (1.74g, 76%).
 

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Related Functional Groups of
[ 114878-60-3 ]

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Related Parent Nucleus of
[ 114878-60-3 ]

Piperazines

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