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[ CAS No. 1150114-44-5 ]

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Chemical Structure| 1150114-44-5
Chemical Structure| 1150114-44-5
Structure of 1150114-44-5 * Storage: {[proInfo.prStorage]}

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Product Details of [ 1150114-44-5 ]

CAS No. :1150114-44-5 MDL No. :MFCD10696632
Formula : C7H9BO5 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :183.95 g/mol Pubchem ID :46739470
Synonyms :

Safety of [ 1150114-44-5 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1150114-44-5 ]

  • Downstream synthetic route of [ 1150114-44-5 ]

[ 1150114-44-5 ] Synthesis Path-Downstream   1~16

  • 1
  • [ 32084-59-6 ]
  • [ 1150114-44-5 ]
  • [ 1285702-88-6 ]
  • 2
  • [ 32084-59-6 ]
  • [ 1150114-44-5 ]
  • [ 1327166-64-2 ]
  • 3
  • [ 268733-18-2 ]
  • [ 1150114-44-5 ]
  • ethyl 5-(4-amino-2,6-bis(trifluoromethyl)phenyl)furan-2-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With potassium phosphate; chloro(2-dicyclohexylphosphino-2?,4?,6?-triisopropyl-1,1?-biphenyl)[2-(2?-amino-1,1?-biphenyl?)]palladium(II); In tetrahydrofuran; water; at 20.0℃; for 2.0h; synthesis of ethyl 5 -(4-amino-2, 6-bis(trifluoromethyl)phenyl)furan-2-carboxylate (143): 4-Bromo-3,5-bis(trifluoromethyl)aniline (142; 8 g, 26 mmol), 5- (ethoxycarbonyl)furan-2-ylboronic acid (7.2 g, 39 mmol), catalyst (2.1 g, 2.6 mmol) and K3P04 (16.5 g, 78 mmol) were added to a mixture of H20 (156 mL) and THF (300 mL). The mixture was degassed and stirred at room temperature for 2 h, extracted with EtOAc (300 mL X 2). The combined organic solvents were concentrated under reduced pressure and purified by silica gel chromatography (10-30% EtOAc/petroleum ether) to give 4.6 g of ethyl 5-(4- amino-2, 6-bi s(trifluoromethyl)phenyl)furan-2-carboxylate 143 as brown solid (48% yield). LCMS: m/z 368.0 [M+H], tR = 1.91 mm
  • 4
  • [ 1150114-44-5 ]
  • (E)-3-(6-aminopyridin-3-yl)-N-((5-(4-(5-(3,3-difluoroazetidine-1-carbonyl)pyridin-2-yl)-2,6-bis(trifluoromethyl)phenyl)furan-2-yl)methyl)acrylamide [ No CAS ]
  • 5
  • [ 1150114-44-5 ]
  • ethyl 5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-carboxylate [ No CAS ]
  • 6
  • [ 1150114-44-5 ]
  • 5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-carboxylic acid [ No CAS ]
  • 7
  • [ 1150114-44-5 ]
  • 5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-carboxamide [ No CAS ]
  • 8
  • [ 1150114-44-5 ]
  • 5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-carbonitrile [ No CAS ]
  • 9
  • [ 1150114-44-5 ]
  • (5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-yl)methanamine [ No CAS ]
  • 10
  • [ 1150114-44-5 ]
  • tert-butyl (5-(4-bromo-2,6-bis(trifluoromethyl)phenyl)furan-2-yl)methylcarbamate [ No CAS ]
  • 11
  • [ 1150114-44-5 ]
  • tert-butyl (5-(4-(5-(3,3-difluoroazetidine-1-carbonyl)pyridin-2-yl)-2,6-bis(trifluoromethyl)phenyl)furan-2-yl)methylcarbamate [ No CAS ]
  • 12
  • [ 1150114-44-5 ]
  • (6-(4-(5-(aminomethyl)furan-2-yl)-3,5-bis(trifluoromethyl)phenyl)pyridin-3-yl)(3,3-difluoroazetidin-1-yl)methanone [ No CAS ]
  • 13
  • [ 65766-32-7 ]
  • [ 1150114-44-5 ]
  • ethyl 5-(6-(methylamino)pyrimidin-4-yl)furan-2-carboxylate [ No CAS ]
  • 14
  • [ 1150114-44-5 ]
  • N-((3S,4S)-4-(4-chlorophenyl)piperidin-3-yl)-5-(6-(methylamino)pyrimidin-4-yl)furan-2-carboxamide [ No CAS ]
  • 15
  • [ 1150114-44-5 ]
  • C26H30ClN5O4 [ No CAS ]
  • 16
  • [ 1150114-44-5 ]
  • 5-(6-(methylamino)pyrimidin-4-yl)furan-2-carboxylic acid [ No CAS ]
Historical Records

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[ 1150114-44-5 ]

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