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Chemical Structure| 117346-07-3 Chemical Structure| 117346-07-3

Structure of 117346-07-3

Chemical Structure| 117346-07-3

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Product Details of [ 117346-07-3 ]

CAS No. :117346-07-3
Formula : C14H8N2O5
M.W : 284.22
SMILES Code : O=C(N1C2=CC=C([N+]([O-])=O)C=C2O)C3=CC=CC=C3C1=O

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Application In Synthesis of [ 117346-07-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 117346-07-3 ]

[ 117346-07-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 117346-07-3 ]
  • [ 221037-98-5 ]
  • 2-(2-(3-iodophenoxy)-4-nitrophenyl)isoindoline-1,3-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
61.1% With pyridine; pyridine N-oxide; oxygen; copper diacetate; In dichloromethane; at 20℃; for 72h;Molecular sieve; Compound 3f was obtained from 2 using the proceduredescribed above for 3e, using 3-iodophenyl boronic acid. The crudeproduct was purified by chromatography on silica gel with CHCl3/hexane/acetone = 1:18:1 to provide 3f (522.7 mg, 61.1percent) as a beigepowder: mp: 175?176 C; 1H NMR (600 MHz, DMSO-d6) d ppm:8.22 (dd, J = 2.4, 8.6 Hz, 1H), 7.99 (dd, J = 2.9, 5.5 Hz, 2H), 7.93(dd, J = 2.9, 5.5 Hz, 2H), 7.89 (d, J = 8.8 Hz, 1H), 7.84 (d, J = 2.2 Hz,1H), 7.52 (d, J = 7.8 Hz, 1H), 7.40 (t, J = 2.0 Hz, 1H), 7.16 (t,J = 8.1 Hz, 1H), 7.10 (dd, J = 2.4, 8.2 Hz, 1H); FTIR(KBr) cm1:3480, 1734, 1715; EI-MS m/z: 486 [M]+; HR-MS: calcd forC20H11IN2O5 [M]+: 485.9713; found 485.9718.
 

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