Home Cart 0 Sign in  

[ CAS No. 1187055-81-7 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1187055-81-7
Chemical Structure| 1187055-81-7
Structure of 1187055-81-7 * Storage: {[proInfo.prStorage]}

Quality Control of [ 1187055-81-7 ]

Related Doc. of [ 1187055-81-7 ]

SDS
Alternatived Products of [ 1187055-81-7 ]
Alternatived Products of [ 1187055-81-7 ]

Product Details of [ 1187055-81-7 ]

CAS No. :1187055-81-7 MDL No. :MFCD18383337
Formula : C12H19BO3 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :222.09 g/mol Pubchem ID :-
Synonyms :

Safety of [ 1187055-81-7 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1187055-81-7 ]

  • Downstream synthetic route of [ 1187055-81-7 ]

[ 1187055-81-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 42260-39-9 ]
  • [ 1187055-81-7 ]
  • [ 1241504-96-0 ]
YieldReaction ConditionsOperation in experiment
With potassium phosphate;(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80℃; To a solution 3 (prepared above) in 800 ml of dioxane were added K3PO4 (118 g, 0.561 mol), 2 chloro-4-phenylpyridine (35.5 g, 0.187 mol), and Pd(dppf)Cl2 (6 g, 5.6 mmol). The suspension was stirred at 80 0C overnight, filtered, and concentrated in vacuo. Purification on silica gel afforded 4 as a yellow solid (30 g, 64percent).
  • 2
  • [ 1187055-81-7 ]
  • [ 6693-08-9 ]
  • (1R)-2,2,2-trifluoro-1-methylethylamine hydrochloride [ No CAS ]
  • 3-(5-fluoro-4,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino) pyrimidin-2-yl)cyclohex-2-en-1-one [ No CAS ]
  • 3-(5-fluoro-2,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)pyrimidin-4-yl)cyclohex-2-en-1-one [ No CAS ]
  • 3
  • [ 1187055-81-7 ]
  • [ 6693-08-9 ]
  • (1R)-2,2,2-trifluoro-1-methylethylamine hydrochloride [ No CAS ]
  • 3-(5-fluoro-4,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)pyrimidin-2-yl)cyclohex-2-en-1-ol [ No CAS ]
  • 3-(5-fluoro-2,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)pyrimidin-4-yl)cyclohex-2-en-1-ol [ No CAS ]
  • 4
  • [ 42918-20-7 ]
  • [ 1187055-81-7 ]
  • [ 90930-90-8 ]
YieldReaction ConditionsOperation in experiment
44% With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In 1,2-dimethoxyethane; water at 90℃; for 1h; Inert atmosphere;
44% With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In 1,2-dimethoxyethane; water at 90℃; for 1h; Inert atmosphere; 2.2 Step 2: 2’-allyl-5,6-dihydro-[1,1’-biphenyl]-3(4H)-one Under Ar,1-allyl-2-bromobenzene (step 1,15g,76mmol),3-(4,4,5,5-tetramethyl-1,3,2-dioxaborane- 2-yl)cyclohex-2-en-1-one (16.9g,76mmol),PdCl2(dppf)-CH2Cl2 adduct (3.11g,3.81mmol) and Na2CO3 (24.20g,228mmol) in DME (160mL) The mixture in a mixed solvent with H2O (40 mL) was stirred at 90°C for 1 h. After cooling to room temperature,H2O (200 mL) was added and the resulting mixture was extracted twice with EA. The organic layers were combined,dried over Na2SO4,and concentrated under reduced pressure to obtain a brown oil,which was purified by silica gel column chromatography (eluted with ethyl acetate/hexane from 0% to 20%) to give the title compound as a colorless oil ( 11.3g,44%).
Historical Records

Related Functional Groups of
[ 1187055-81-7 ]

Alkenyls

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 151075-23-9

[ 151075-23-9 ]

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)ethanone

Similarity: 0.94

Organoboron

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Aliphatic Cyclic Hydrocarbons

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 151075-23-9

[ 151075-23-9 ]

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)ethanone

Similarity: 0.94

Ketones

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 151075-23-9

[ 151075-23-9 ]

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)ethanone

Similarity: 0.94

Esters

Chemical Structure| 1187055-94-2

[ 1187055-94-2 ]

5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 1.00

Chemical Structure| 497959-45-2

[ 497959-45-2 ]

5,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enone

Similarity: 0.98

Chemical Structure| 1370008-65-3

[ 1370008-65-3 ]

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopent-2-enone

Similarity: 0.97

Chemical Structure| 151075-23-9

[ 151075-23-9 ]

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)ethanone

Similarity: 0.94