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Chemical Structure| 1192-92-3 Chemical Structure| 1192-92-3

Structure of 1192-92-3

Chemical Structure| 1192-92-3

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Product Details of [ 1192-92-3 ]

CAS No. :1192-92-3
Formula : C6H14Cl2N2
M.W : 185.09
SMILES Code : C1(CC2)NCC2NC1.[H]Cl.[H]Cl
MDL No. :MFCD11506237

Safety of [ 1192-92-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 1192-92-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1192-92-3 ]

[ 1192-92-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 93107-30-3 ]
  • [ 1192-92-3 ]
  • [ 132234-78-7 ]
  • 2
  • [ 24424-99-5 ]
  • [ 1192-92-3 ]
  • [ 858671-91-7 ]
YieldReaction ConditionsOperation in experiment
42% With sodium hydroxide; In water; isopropyl alcohol; at 0℃; for 1.5h; A solution of di-tert-butyldicarbonate (6.5 mmol) in isopropanol (15 mL) was added drop wise to a solution of the diamine (7.06 mmol) in isopropanol (100 mL), water (35mL), and 1 M sodium hydroxide (6.5 mL) at 0 C. The reaction mixture was maintained for 1.5 h at 0 C and was concentrated to-50 ni-L. The aqueous slurry was saturated with solid sodium chloride and the pH adjusted to 10 with 2 M sodium hydroxide. The aqueous layer was extracted with ethyl acetate (3 x 35 mL) and the combined organic layers were washed with brine and dried (magnesium sulfate). The volatiles were removed under reduced pressure to afford the crude mono-protected diamine in 42% yield as a light yellow oil.
 

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