93107-30-3|1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid| Ambeed

CAS No. :	93107-30-3
Formula :	C₁₃H₉F₂NO₃
M.W :	265.21
SMILES Code :	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(F)=C3)C1=O)O
MDL No. :	MFCD01646375
InChI Key :	KNEXGVPHPGXAGF-UHFFFAOYSA-N
Pubchem ID :	5210422

Safety of [ 93107-30-3 ]

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H315-H319-H332-H335
Precautionary Statements:	P261-P280-P305+P351+P338

Application In Synthesis of [ 93107-30-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 93107-30-3 ]

[ 93107-30-3 ] Synthesis Path-Downstream 1~54

1
[ 503-29-7 ]
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-1,4-dihydro-7-[1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;	EXAMPLE 1 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid A mixture of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid (1.591 g, 6 mmole), acetonitrile (70 ml), azetidine (390 mg, 6.8 mmole) and DBU (913 mg, 6 mmole) were heated at reflux. After only 5 minutes of heating, it was observed that crystalline material was precipitating. After 5 additional minutes of heating, the hot solution was filtered. The reaction mixture was then allowed to cool at room temperature for 1 hour. The solid material that precipitated was collected by filtration, washed first with acetonitrile and then with ethyl ether and then dried to give 650 mg of the title compound, m.p. 298°-299° C. (dec.). NMR(DMSO-D6): 1.12-1.13 d and 1.26-1.28 d, 4H of cyclopropane; 2.3-2.4, m, 2H of C3 'azetidine; 3.2-3.7, q, 1H of cyclopropane; 4.19-4.24, q, 4H of azetidine C2 ' and C4 '; 6.82- 6.85, d, 1H of C8; 7.74-7.78, d, 1H of C5; 8.55, s, 1H of C2.

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.
[2]Patent: US5039683,1991,A .

2
[ 110-85-0 ]
[ 93107-30-3 ]
[ 93107-08-5 ]

References: [1]Journal of Heterocyclic Chemistry,1987,vol. 24,p. 181 - 185.

3
[ 505-66-8 ]
[ 93107-30-3 ]
[ 118330-11-3 ]

References: [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 142 - 146.

4
[ 90152-00-4 ]
[ 93107-30-3 ]
[ 118382-88-0 ]

References: [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 611 - 620.

5
[ 5625-67-2 ]
[ 93107-30-3 ]
[ 103237-52-1 ]

References: [1]Arzneimittel-Forschung/Drug Research,1986,vol. 36,p. 1545 - 1549.

6
[ 45347-82-8 ]
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3'-hydroxy-1'-azetidinyl]-4-oxo-3-quinolinecarboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

7
[ 57260-73-8 ]
[ 93107-30-3 ]
7-((2-((tert-butoxycarbonyl)amino)ethyl)amino)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
58%	With pyridine; at 120℃; for 16h;	The corresponding amine (2.07 mmol, 1.1 eq) was added to a suspension of <strong>[93107-30-3]1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid</strong> (Q1b) (500 mg, 1.89 mmol, 1 eq) in pyridine (10 mL). The resulting mixture was heated at reflux at 120 C for 16 h. The resultant mixture was concentrated under reduced pressure. The crude product was isolated by vacuum filtration and washed with EtOAc, water and Et2O to afford the Boc-protected aminated quinolone

References: [1]Bioorganic and Medicinal Chemistry,2019,vol. 27.
[2]Arzneimittel-Forschung/Drug Research,1986,vol. 36,p. 1545 - 1549.

8
[ 114373-07-8 ]
[ 93107-30-3 ]
[ 132233-67-1 ]

References: [1]Journal of Medicinal Chemistry,1991,vol. 34,p. 1155 - 1161.

9
[ 28795-81-5 ]
[ 93107-30-3 ]
[ 123187-97-3 ]

References: [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 142 - 146.

10
[ 93107-30-3 ]
[ 110842-63-2 ]
[ 123187-95-1 ]

Yield	Reaction Conditions	Operation in experiment
	With pyridine;	EXAMPLE 131 1-Cyclopropyl-6-fluoro-7-[3-(fluoromethyl)-1-piperazinyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid A suspension of 530.4 mg of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 90.7 mg of 2-(fluoromethyl)piperazine and 2 ml of pyridine was heated at 115 C. for 30 minutes, then filtered and the filtrate refrigerated overnight. The resulting crystals were collected, washed with water, ether and dried, giving 262 mg of the desired compound as light yellow crystals, mp 202-203 C.

References: [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 142 - 146.
[2]Patent: US4940710,1990,A .

11
[ 93107-30-3 ]
[ 123187-94-0 ]
[ 123187-98-4 ]

References: [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 142 - 146.

12
[ 127371-54-4 ]
[ 93107-30-3 ]

References: [1]Synthesis,2006,p. 963 - 968.

13
methyl 2-cyclopropylaminomethylene-3-(2,4,5-trifluorophenyl)-3-oxopropanoate [ No CAS ]
[ 93107-30-3 ]

References: [1]Synthesis,2006,p. 963 - 968.

14
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-((S)-3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Bioorganic and Medicinal Chemistry,2005,vol. 13,p. 2451 - 2458.

15
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-((R)-3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Bioorganic and Medicinal Chemistry,2005,vol. 13,p. 2451 - 2458.

16
[ 93107-30-3 ]
7-((3S)-amino-(4R)-ethylpiperidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid dihydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2003,vol. 46,p. 3655 - 3661.

17
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-((2R,3S)-2-methyl-3-methylamino-azetidin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1994,vol. 37,p. 4195 - 4210.

18
[ 93107-30-3 ]
7-((2R,3S)-3-Aminomethyl-2-methyl-azetidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1994,vol. 37,p. 4195 - 4210.

19
[ 93107-30-3 ]
1-Cyclopropyl-7-((2R,3S)-3-ethylaminomethyl-2-methyl-azetidin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1994,vol. 37,p. 4195 - 4210.

20
[ 93107-30-3 ]
[ 105112-37-6 ]

References: [1]Journal of Medicinal Chemistry,1988,vol. 31,p. 983 - 991.
[2]Journal of Heterocyclic Chemistry,1987,vol. 24,p. 181 - 185.

21
[ 101799-76-2 ]
[ 93107-30-3 ]

References: [1]Journal of Medicinal Chemistry,1988,vol. 31,p. 983 - 991.
[2]Liebigs Annalen der Chemie,1987,p. 29 - 37.
[3]Patent: US4940710,1990,A .

22
[ 93107-30-3 ]
(R)-7-[3-(1-Amino-1-methylethyl)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1994,vol. 37,p. 733 - 738.

23
[ 93107-30-3 ]
7-[(S)-3-(1-Amino-1-methyl-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1994,vol. 37,p. 733 - 738.

24
[ 93107-30-3 ]
[ 103222-12-4 ]

References: [1]Arzneimittel-Forschung/Drug Research,1986,vol. 36,p. 1545 - 1549.

25
[ 93107-30-3 ]
[ 132233-67-1 ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

26
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3'-aminomethyl-1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

27
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-7-(3-methylamino-1-azetidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

28
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-7-(3-amino-3-methyl-1-azetidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

29
[ 93107-30-3 ]
[ 132770-51-5 ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

30
[ 93107-30-3 ]
[ 132770-06-0 ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

31
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-aminomethyl-3-methyl-1-azetidinyl)-quinoline-3-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

32
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-7-(3-ethylaminomethyl-1-azetidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

33
[ 93107-30-3 ]
1-cyclopropyl-6-fluoro-7-(3-ethylaminomethyl-3-methyl-1-azetidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

34
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-{3-methyl-3-[methyl-(2-oxo-propyl)-amino]-azetidin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 801 - 810.

35
[ 93107-30-3 ]
7-[(S)-3-((R)-1-Amino-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

36
[ 93107-30-3 ]
7-[(S)-3-((S)-1-Amino-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

37
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-[(R)-3-((S)-1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrofluoride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

38
[ 93107-30-3 ]
7-[(R)-3-((S)-1-Amino-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

39
[ 93107-30-3 ]
7-[(R)-3-((R)-1-Amino-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

40
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-[(R)-3-((R)-1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

41
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-[(S)-3-((S)-1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

42
[ 93107-30-3 ]
1-Cyclopropyl-6-fluoro-7-[(S)-3-((R)-1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 871 - 882.

43
[ 88419-56-1 ]
[ 93107-30-3 ]

References: [1]Liebigs Annalen der Chemie,1987,p. 29 - 37.
[2]Patent: US4940710,1990,A .

44
[ 98349-24-7 ]
[ 93107-30-3 ]

References: [1]Liebigs Annalen der Chemie,1987,p. 29 - 37.
[2]Patent: WO2018/220365,2018,A1 .
[3]Patent: US4940710,1990,A .

45
[ 101799-75-1 ]
[ 93107-30-3 ]

References: [1]Liebigs Annalen der Chemie,1987,p. 29 - 37.
[2]Patent: US4940710,1990,A .

46
[ 104600-15-9 ]
[ 93107-30-3 ]

References: [1]Liebigs Annalen der Chemie,1987,p. 29 - 37.
[2]Patent: US4940710,1990,A .

47
[ 93107-30-3 ]
[ 137787-79-2 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

48
[ 93107-30-3 ]
[ 127803-30-9 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

49
[ 93107-30-3 ]
[ 122857-90-3 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

50
[ 93107-30-3 ]
[ 137787-81-6 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

51
[ 93107-30-3 ]
[ 122858-16-6 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

52
[ 93107-30-3 ]
[ 137787-78-1 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

53
[ 93107-30-3 ]
[ 137811-37-1 ]

References: [1]Journal of Heterocyclic Chemistry,1991,vol. 28,p. 1581 - 1585.

54
[ 110600-97-0 ]
[ 93107-30-3 ]

References: [1]Journal of Heterocyclic Chemistry,1987,vol. 24,p. 181 - 185.

Historical Records

Technical Information

• Alkyl Halide Occurrence • Arndt-Eistert Homologation • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • Grignard Reaction • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hunsdiecker-Borodin Reaction • Hydride Reductions • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Preparation of Carboxylic Acids • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions of Carboxylic Acids • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stobbe Condensation • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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[ 93107-30-3 ]

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[ 93107-30-3 ]

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Precautionary Statements-General
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P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

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CAS No.: 93107-30-3

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CAS No.: 93107-30-3

Alternative Products

Product Details of [ 93107-30-3 ]

Safety of [ 93107-30-3 ]

Application In Synthesis of [ 93107-30-3 ]

[ 93107-30-3 ] Synthesis Path-Downstream 1~54

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Related Functional Groups of
[ 93107-30-3 ]

Fluorinated Building Blocks

Ketones

Carboxylic Acids

Related Parent Nucleus of
[ 93107-30-3 ]

Quinolines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Molarity Calculator

Total Compounds Calculator

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{[proInfo.proName]}

CAS No.: 93107-30-3

{[proInfo.proName]}

CAS No.: 93107-30-3

Alternative Products

Product Details of [ 93107-30-3 ]

Safety of [ 93107-30-3 ]

Application In Synthesis of [ 93107-30-3 ]

[ 93107-30-3 ] Synthesis Path-Downstream 1~54

Related Products

Historical Records

Technical Information

Categories

Related Functional Groups of [ 93107-30-3 ]

Fluorinated Building Blocks

Ketones

Carboxylic Acids

Related Parent Nucleus of [ 93107-30-3 ]

Quinolines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Molarity Calculator

Total Compounds Calculator

Dissolution Calculator

Related Functional Groups of
[ 93107-30-3 ]

Related Parent Nucleus of
[ 93107-30-3 ]