CAS No. :	120-32-1
Formula :	C₁₃H₁₁ClO
M.W :	218.68
SMILES Code :	OC1=CC=C(Cl)C=C1CC2=CC=CC=C2
Synonyms :	Clorofene
MDL No. :	MFCD00020140
InChI Key :	NCKMMSIFQUPKCK-UHFFFAOYSA-N
Pubchem ID :	8425

Safety of 2-Benzyl-4-chlorophenol

GHS Pictogram:
Signal Word:	Danger
Hazard Statements:	H302-H315-H318-H335-H410
Precautionary Statements:	P261-P273-P280-P305+P351+P338
Class:	9
UN#:	3077
Packing Group:	Ⅲ

Application In Synthesis of 2-Benzyl-4-chlorophenol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 120-32-1 ]

[ 120-32-1 ] Synthesis Path-Downstream 1~55

1
[ 50-00-0 ]
[ 120-32-1 ]
6,6'-dibenzyl-4,4'-dichloro-2,2'-methanediyl-di-phenol [ No CAS ]

References: [1]Patent: US2724000,1951, .

2
[ 57630-57-6 ]
[ 120-32-1 ]
[ 104440-68-8 ]

References: [1]Patent: DE951928,1950, .

3
[ 120-32-1 ]
[ 17026-49-2 ]
2,6-bis-(3-benzyl-5-chloro-2-hydroxy-benzyl)-4-chloro-phenol [ No CAS ]

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 5579,5581.

4
[ 120-32-1 ]
[ 19578-81-5 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

5
[ 120-32-1 ]
benzyl 2-benzyl-4-chlorophenyl ether [ No CAS ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

6
[ 28994-41-4 ]
[ 120-32-1 ]

References: [1]Patent: DE703955,1939, .
DRP/DRBP Org.Chem.,.

7
[ 7700-27-8 ]
[ 120-32-1 ]
[ 101879-94-1 ]
[ 106-48-9 ]
[ 108-88-3 ]

References: [1]Journal of the Chemical Society,1959,p. 1873,1875.

8
[ 100-44-7 ]
[ 1193-00-6 ]
[ 120-32-1 ]
[ 7700-27-8 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

9
[ 124-41-4 ]
[ 100-44-7 ]
[ 106-48-9 ]
[ 120-32-1 ]
[ 7700-27-8 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

10
[ 100-44-7 ]
[ 106-48-9 ]
[ 1193-00-6 ]
[ 120-32-1 ]
[ 7700-27-8 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

11
[ 100-44-7 ]
[ 106-48-9 ]
[ 120-32-1 ]

References: [1]Journal of the American Chemical Society,1932,vol. 54,p. 3315,3323.
[2]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.
[3]Patent: DE824058,1948, .
DRP/DRBP Org.Chem.,.

12
[ 120-32-1 ]
[ 98-88-4 ]
[ 40395-11-7 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

13
[ 120-32-1 ]
[ 88-11-9 ]
[ 101784-08-1 ]

References: [1]Journal of the American Chemical Society,1957,vol. 79,p. 747.

14
[ 538-86-3 ]
[ 106-48-9 ]
[ 120-32-1 ]

References: [1]Patent: DE734567,1939, .

15
[ 103-50-4 ]
[ 106-48-9 ]
[ 120-32-1 ]

References: [1]Patent: DE734567,1939, .

16
[ 106-48-9 ]
[ 100-51-6 ]
[ 120-32-1 ]

References: [1]Synthetic Communications,2008,vol. 38,p. 2684 - 2691.
[2]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

17
[ 50-00-0 ]
[ 120-32-1 ]
[ 124-40-3 ]
[ 52938-83-7 ]

References: [1]Journal of the American Chemical Society,1952,vol. 74,p. 2940.

18
[ 120-32-1 ]
[ 98-09-9 ]
benzenesulfonic acid-(2-benzyl-4-chloro-phenyl ester) [ No CAS ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

19
[ 120-32-1 ]
[ 98-59-9 ]
toluene-4-sulfonic acid-(2-benzyl-4-chloro-phenyl ester) [ No CAS ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

20
[ 120-32-1 ]
[ 79-44-7 ]
[ 101167-64-0 ]

References: [1]Journal of the American Chemical Society,1957,vol. 79,p. 747.

21
carbonic acid bis-(4-chloro-2-chloromethyl-phenyl ester) [ No CAS ]
[ 71-43-2 ]
[ 120-32-1 ]

References: [1]Patent: DE723950,1939, .
DRP/DRBP Org.Chem.,.

22
[ 120-32-1 ]
[ 567-19-1 ]
[ 68229-66-3 ]

References: [1]Journal of Pharmaceutical Sciences,1978,vol. 67,p. 1323 - 1325.

23
[ 110-52-1 ]
[ 120-32-1 ]
[ 343229-39-0 ]

References: [1]Journal of Medicinal Chemistry,1981,vol. 24,p. 145 - 148.

24
[ 120-32-1 ]
Benzyl-p-benzochinon [ No CAS ]

References: [1]Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases,1988,vol. 84,p. 3249 - 3256.

25
[ 85-19-8 ]
[ 120-32-1 ]

References: [1]Chemical and Pharmaceutical Bulletin,1979,vol. 27,p. 1490 - 1494.

26
[ 120-32-1 ]
[ 106-89-8 ]
[ 19809-68-8 ]

References: [1]Journal of Pharmaceutical Sciences,1968,vol. 57,p. 1447 - 1448.

27
[ 7446-70-0 ]
[ 100-44-7 ]
[ 106-48-9 ]
petroleum ether [ No CAS ]
[ 120-32-1 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

Yield	Reaction Conditions	Operation in experiment
		Surprisingly, it has now been found that new active compound combinations of at least one phenol derivative such as, for example, ... 3-methyl-4-chlorophenol o-phenylphenol m-phenylphenol p-phenylphenol 2-benzyl-4-chlorophenol
		Examples of fungicides with which the 4-nitro-2-trichloromethylphenylsulfenamides according to the invention may be combined are as follows: ... barium salt of pentachlorophenol pentachlorophenyl acetate pentachlorobenzyl alcohol di-(5-chloro-2-hydroxyphenyl)-methane phenyl-(5-chloro-2-hydroxyphenyl)-methane N-trichloromethylthiotetrahydrophthalimide N-trichloromethylthiophthalimide N-fluorodichloromethylthiophthalimide ...
		Examples of fungicides which can be combined with the compounds of the invention are: ... barium salt of pentachlorophenol (5B) pentachlorophenyl acetate pentachlorobenzyl alcohol di-(5-chloro-2-hydroxyphenyl)-methane (dichlorophen) phenyl-(5-chloro-2-hydroxyphenyl)-methane N-trichloromethylthiotetrahydrophthalimide (captan) N-trichloromethylthiophthalimide (folpet) N-(1,1,2,2-tetrachloroethylthio)-tetrahydrophthalimide (captafol) ...

The following list of fungicides with which the N-(fluorodichloromethylthio)-benzanilides of the invention may be combined is intended to illustrate, but not restrict, possible combinations: ... barium salt of pentachlorophenol (5 B) pentachlorophenyl acetate pentachlorobenzyl alcohol di-(5-chloro-2-hydroxyphenyl)-methane (dichlorophen) phenyl-(5-chloro-2-hydroxyphenyl)-methane N-trichloromethylthiotetrahydrophthalimide (captan) N-trichloromethylthiophthalimide (folpet) N-fluorodichloromethylthio phthalimide ...

29
[ 67-66-3 ]
[ 120-32-1 ]
[ 7782-50-5 ]
[ 19578-81-5 ]

References: [1]Journal of the American Chemical Society,1933,vol. 55,p. 4639,4640.

30
[ 7446-70-0 ]
carbonic acid bis-(4-chloro-2-chloromethyl-phenyl ester) [ No CAS ]
[ 71-43-2 ]
[ 120-32-1 ]

References: [1]Patent: DE723950,1939, .
DRP/DRBP Org.Chem.,.

31
[ 106-48-9 ]
[ 497949-70-9 ]
[ 120-32-1 ]
[ 7700-27-8 ]

References: [1]Organic Letters,2003,vol. 5,p. 193 - 196.

32
[ 120-32-1 ]
2-benzyl-4-chlorophenylsulfamate [ No CAS ]

References: [1]Tetrahedron Asymmetry,2004,vol. 15,p. 1019 - 1026.

33
[ 120-32-1 ]
[ 77-78-1 ]
[ 40395-13-9 ]

References: [1]Environmental Pollution,2007,vol. 147,p. 176 - 186.

34
[ 120-32-1 ]
6-chloro-4-phenyl-3,4-dihydro-benzo[e][1,2,3]oxathiazane-2,2-dioxide [ No CAS ]

References: [1]Tetrahedron Asymmetry,2004,vol. 15,p. 1019 - 1026.

35
[ 100-51-6 ]
BocNH-C(=NBoc)-SCH₂-terminated resin [ No CAS ]
[ 120-32-1 ]

References: [1]Organic Letters,2003,vol. 5,p. 193 - 196.

36
[ 120-32-1 ]
[4-(2-Benzyl-4-chloro-phenoxy)-butyl]-methyl-amine [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1981,vol. 24,p. 145 - 148.

37
[ 120-32-1 ]
[4-(2-Benzyl-4-chloro-phenoxy)-butyl]-dimethyl-amine [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1981,vol. 24,p. 145 - 148.

38
[ 39489-74-2 ]
[ 120-32-1 ]

References: [1]Patent: DE723950,1939, .
DRP/DRBP Org.Chem.,.

39
[ 120-32-1 ]
N,N-Diaethyl-3-<2-benzyl-4-chlorphenoxy>-2-hydroxy-propylamin [ No CAS ]

References: [1]Journal of Pharmaceutical Sciences,1968,vol. 57,p. 1447 - 1448.

40
[ 120-32-1 ]
1-[2-(Amino-phenyl-methyl)-4-chloro-phenoxy]-3-chloro-propan-2-ol [ No CAS ]

References: [1]Journal of Pharmaceutical Sciences,1968,vol. 57,p. 1447 - 1448.

41
[ 120-32-1 ]
[ 78-95-5 ]
1-(2-benzyl-4-chlorophenoxy)-propan-2-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; potassium iodide; In acetone; for 20h;Heating / reflux;	5 g of 2-benzyl-4-chlorophenol, 2.6 ml of chloroacetone, 1.38 g of potassium carbonate and 0.34 g of potassium iodide are dissolved in 50 ml of acetone and boiled under reflux for 20 h. After cooling, the precipitate is filtered, concentrated by evaporation, the residue dissolved in ethyl acetate, the solution washed three times with a In sodium hydroxide solution, then with saturated sodium chloride solution, dried with magnesium sulphate and concentrated by evaporation under vacuum. After recrystallisation from diethylether, 1-(2-benzyl-4-ch1orophenoxy)-propan-2-one is obtained as a white powder with a melting point of 65-6C.

References: [1]Patent: WO2004/793,2003,A2 .Location in patent: Page 35.

42
[ 120-32-1 ]
[ 92044-51-4 ]

Yield	Reaction Conditions	Operation in experiment
100%	With hydrogenchloride; potassium nitrate; sodium nitrite; In diethyl ether; water; for 2h;	To a mixture of 2-phenylmethyl-3-chlorophenol (5.00 g, 22.9 mmol) in Et2O (20 mL) and 6N HCl (50 mL), KNO3 (2.30 g, 22.9 mmol) and NaNO2 (20 mg, catalytic) were added sequentially. The resulting mixture was stirred for 2 hours, diluted with water and extracted with ethyl acetate. The organic layer was washed with water and brine, dried over MgSO4 and filtered. The filtrate was concentrated under reduced pressure to give 99 (6.0 g, 100%).

References: [1]Patent: US2004/63955,2004,A1 .Location in patent: Page 21; 39.

43
[ 120-32-1 ]
[ 109-64-8 ]
[ 787576-03-8 ]

Yield	Reaction Conditions	Operation in experiment
72%	With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 - 80℃; for 1h;	Powdered K2CO3 (2.07 g, 15.0 mmol) is added to a stirred solution of 2-benzyl-4- chlorophenol (2.19 g, 10.0 mmol) and 1,3-dibromopropane (3.05 mL, 30.0 mmol) in anhydrous DMF (20 mL) at ambient temperature under nitrogen. The mixture is heated at 80 C for 1 hour. At ambient temperature, EtOAc (100 ML) and water (150 mL) are added to the mixture. The organic layer is separated, dried over MGS04, filtered and concentrated. The crude product is chromatographed on silica (gradient 0-2% EtOAc in hexane) to give 2.45 g (7.21 mmol, 72% yield) of the title compound as a white solid. EIMS: m/z 338 (M+, 35C1, 79Br), 340 (M+, 37C1, 79BR OR 35C1, 8LBR), 342 (M+, 37Cl, 8LBR).

References: [1]Patent: WO2004/94386,2004,A1 .Location in patent: Page 28-29.

44
[ 120-32-1 ]
[ 137886-82-9 ]
4'-chloro-2'-benzylphenyl 2,3,4,6-tetra-O-acetyl-5-thio-β-D-glucopyranoside [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
56%	With triphenylphosphine; diethylazodicarboxylate; In toluene; at 0 - 20℃; for 12h;	Example 19 Preparation of 4'-chloro-2'-benzylphenyl 2,3,4,6-tetra-O-acetyl-5-thio-beta-D-glucopyranoside 2,3,4,6-Tetra-O-acetyl-5-thio-D-glucopyranose (200 mg, 0.549 mmol), 4-chloro-2-benzylphenol (601 mg, 2.75 mmol), triphenylphosphine (191 mg, 1.10 mmol) and toluene (1.6 mL) were mixed, and to the resulting mixture, diethyl azodicarboxylate (40% in toluene, 0.48 mL, 1.10 mmol) was then slowly added dropwise in ice. After stirring at room temperature for 12 hours, the reaction mixture was concentrated and the resulting residue was purified by silica gel column chromatography (hexane:ethyl acetate = 7:3) to give the titled compound (173 mg, 56%). 1H-NMR (300 MHz, CDCl3): delta 1.91 (s, 3H), 2.01 (s, 3H), 2.05 (s, 3H), 2.06 (s, 3H), 3.28 (m, 1H), 3.88 (s, 2H), 4.14 (dd, J = 3.7, 12.0Hz, 1H), 4.30 (dd, J = 5.3, 12.0Hz, 1H), 5.16 (dd, J = 8.8, 9.5Hz, 1H), 5.31 (d, J = 8.6Hz, 1H), 5.39 (dd, J = 9.5, 10.3Hz, 1H), 5.60 (dd, J = 8.6, 8.8Hz, 1H), 7.03-7.35 (m, 8H). ESI m/z = 587, 589 (M+Na). mp 111.0-114.0C.

References: [1]Patent: EP1528066,2005,A1 .Location in patent: Page/Page column 26.

45
[ 850792-65-3 ]
[ 120-32-1 ]
C₃₀H₂₇ClO₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate;copper(l) chloride; In 1-methyl-pyrrolidin-2-one; at 120℃;Heating;	Example 8 3-f 4- [3- (2-Benzyl-4-chloro-phenoxy)-phenoxy]-2-methyl-phenyl}-propionic acid A solution of 3- [4- (3-bromo-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester (0.1 g, 0.3 mmol), 2-benzyl-4-chloro-phenol (69 mg, 0.32 mmol), copper (I) chloride (14 mg, 0.14 mmol), 2,2, 6,6-tetramethyl-3, 5-heptanedione (0.01 mL, 0.07 mmol), and cesium carbonate (113 mg, 0.35 mmol) in NMP (3 mL) is heated to 120 C. The reaction is stirred overnight and cooled to rt. The reaction is then quenched with IN aqueous HCl and extracted with ethyl ether. The organic is washed with brine, dried over sodium sulfate, and filtered. The solvent is removed to afford the crude ester intermediate. The intermediate is treated with 5N NaOH (0.4 mL, 2.2 mmol) in MeOH (5 mL) and heated to reflux. The reaction is stirred at reflux for 2 hours and then cooled. The reaction is quenched with IN aqueous HCl to obtain pH=4. The aqueous layer is extracted with ethyl ether. The organic layer is washed with brine, dried over sodium sulfate, and filtered. The solvent is removed to afford the crude product. The crude is purified by prep HPLC to afford 63 mg (47%) of desired product NMR (400 MHz, CDCl3) ; MS (ES+) mlz mass calculated for C29H25ClO4 472, found 473 and 475 (M + 1 andM+3, 100%).

References: [1]Patent: WO2005/37763,2005,A1 .Location in patent: Page/Page column 60-61.

46
[ 120-32-1 ]
[ 106-89-8 ]
3-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; mercury; In butanone;	(A) 3-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane A suspension containing 21.87 g of 2-benzyl-4-chlorophenol, 27.76 g of 1-chloro-2,3-epoxypropane and 27.64 g of potassium carbonate in 200 ml of butanone is refluxed for 12 hours. The inorganic salts formed are filtered off and drained. The solvent and excess 1-chloro-2,3-epoxypropane are evaporated off under vacuum and the residue is distilled at between 160 C. and 180 C. under 0.01 mm of mercury. The colorless oil obtained solidifies rapidly. Weight: 21.7 g Yield: 79%

References: [1]Patent: US5036077,1991,A .

47
[ 80-05-7 ]
concentrated NaOH [ No CAS ]
N-(hydroxyethyl)-ethylenediamine [ No CAS ]
[ 112-34-5 ]
[ 120-32-1 ]
[ 148-18-5 ]

Yield	Reaction Conditions	Operation in experiment
		0.5 part of the sodium salt of diethyldithiocarbamate, 1.5 parts of a 30% liquid dispersion of 2,5-di-tert-butyl-hydroquinone, or 1.0 part of a 50% liquid vatting accelerator of the following composition: 20 parts of 4,4'-isopropylidene-bis(phenol), 15 parts of 2-benzyl-4-chlorophenol, 15 parts of N-(hydroxyethyl)-ethylenediamine, 5 parts of concentrated NaOH 36Be', and 45 parts of butyl diglycol.

References: [1]Patent: US4519805,1985,A .

48
[ 100-39-0 ]
[ 106-48-9 ]
[ 1050575-40-0 ]
[ 120-32-1 ]

References: [1]Tetrahedron Letters,2008,vol. 49,p. 5039 - 5042.

49
[ 100-39-0 ]
[ 106-48-9 ]
[ 1050575-40-0 ]
[ 120-32-1 ]
[ 7700-27-8 ]
benzyl 2-benzyl-4-chlorophenyl ether [ No CAS ]

References: [1]Tetrahedron Letters,2008,vol. 49,p. 5039 - 5042.

50
[ 120-32-1 ]
[ 28994-41-4 ]

References: [1]ChemSusChem,2011,vol. 4,p. 98 - 103.

51
[ 120-32-1 ]
[ 1351862-40-2 ]

References: [1]Journal of Medicinal Chemistry,2011,vol. 54,p. 8582 - 8591.

52
[ 120-32-1 ]
[ 1351862-41-3 ]

References: [1]Journal of Medicinal Chemistry,2011,vol. 54,p. 8582 - 8591.

53
[ 120-32-1 ]
[ 1351862-32-2 ]

References: [1]Journal of Medicinal Chemistry,2011,vol. 54,p. 8582 - 8591.
[2]Patent: WO2013/56003,2013,A2 .

54
[ 120-32-1 ]
[ 1351862-39-9 ]

References: [1]Journal of Medicinal Chemistry,2011,vol. 54,p. 8582 - 8591.

55
[ 120-32-1 ]
[ 540-51-2 ]
[ 68032-82-6 ]

Yield	Reaction Conditions	Operation in experiment
67%		General procedure: Diisopropyl azodicarboxylate (DIAD, 5.0 mmol) was added slowly to a solution of o- arylphenols (48 a-h) (4.6 mmol)la, 2a and triphenylphosphine (5.0 mmol) in THF (10.0 mL) at room temperature. After stirring the reaction mixture for 10 minutes, 2-bromoethanol (0.35' mL, 5.0 mmol) was added to it and the resulting mixture was stirred at room temperature for 24 h. After completion, the reaction mixture was concentrated under reduced pressure and purified by column chromatography (Si02, hexane/EtOAc 80:20) to give 49 a-h; 2-benzyl-l-(2-bromoethoxy)-4-chlorobenzene (49 a) (1.2 g, 67%) 1H NMR (500 MHz, CDC13) delta 7.15 (s, 1H), 7.14 (dd, J= 2.0, 8.1 Hz, 1H), 7.12 (dd, J= 2.1, 8.3 Hz, 1H), 7.04 (d, J= 7.9 Hz, 1H), 6.96 (d, J= 2.5 Hz, 1H), 6.76 (d, J= 2.1 Hz, 1H), 4.46 (t, J - 4.7 Hz, 2H), 4.03 (s, 2H), 3.60 (t, J= 4.7 Hz, 2H). 13C NMR (126 MHz, CDC13) delta 154.48, 136.07, 132.63, 130.31, 129.75, 129.20, 127.50, 127.02, 126.50, 116.02, 112.59, 68.23, 32.81, 29.01.

References: [1]Journal of Medicinal Chemistry,2011,vol. 54,p. 8582 - 8591.
[2]Patent: WO2013/56003,2013,A2 .Location in patent: Page/Page column 48.

Precautionary Statements-General
Code	Phrase
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Prevention
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Code	Phrase
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P321
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P378
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P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

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CAS No.: 120-32-1

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CAS No.: 120-32-1

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[ 120-32-1 ] Synthesis Path-Downstream 1~55

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