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Chemical Structure| 1206675-01-5 Chemical Structure| 1206675-01-5

Structure of 1206675-01-5

Chemical Structure| 1206675-01-5

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Product Details of [ 1206675-01-5 ]

CAS No. :1206675-01-5
Formula : C9H13NO3
M.W : 183.20
SMILES Code : OC1=CC=CC=C1CN.CC(O)=O
MDL No. :MFCD29059387
Boiling Point : No data available
InChI Key :IROPMSURBDPOOZ-UHFFFAOYSA-N
Pubchem ID :131674923

Safety of [ 1206675-01-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 1206675-01-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1206675-01-5 ]

[ 1206675-01-5 ] Synthesis Path-Downstream   1~22

  • 1
  • [ 1206675-01-5 ]
  • o-hydroxyphenylmethylamine hydrochloride [ No CAS ]
  • 3
  • [ 626-96-0 ]
  • [ 1206675-01-5 ]
  • C2H4O2*C12H13NO [ No CAS ]
  • 4
  • [ 1121-60-4 ]
  • [ 1206675-01-5 ]
  • [ 763071-62-1 ]
  • 5
  • [ 1206675-01-5 ]
  • [ 194734-57-1 ]
  • [ 1619935-41-9 ]
  • 6
  • [ 1206675-01-5 ]
  • C30H28Al2N2O4 [ No CAS ]
  • 7
  • [ 1206675-01-5 ]
  • C46H60Al2N2O4 [ No CAS ]
  • 8
  • [ 1206675-01-5 ]
  • C30H24Al2Cl4N2O4 [ No CAS ]
  • 9
  • [ 1206675-01-5 ]
  • [ 90-02-8 ]
  • [ 3946-40-5 ]
  • 10
  • [ 1206675-01-5 ]
  • C30H28Al2N2O4 [ No CAS ]
  • C16H17NO2 [ No CAS ]
  • 11
  • [ 1206675-01-5 ]
  • C30H28Al2N2O4 [ No CAS ]
  • C34H36Al2N2O4 [ No CAS ]
  • 12
  • [ 37942-07-7 ]
  • [ 1206675-01-5 ]
  • C22H29NO2 [ No CAS ]
  • 13
  • [ 1206675-01-5 ]
  • [ 90-60-8 ]
  • 2-hydroxybenzylamine-2'-hydroxy-3',5'-chlorobenzylidene [ No CAS ]
  • 14
  • [ 1206675-01-5 ]
  • C16H16BNO2 [ No CAS ]
  • 15
  • [ 1206675-01-5 ]
  • C16H13(2)H3BNO2 [ No CAS ]
  • 16
  • [ 1206675-01-5 ]
  • C25H31BN4O8S [ No CAS ]
  • 17
  • [ 1206675-01-5 ]
  • [ 932-30-9 ]
  • 18
  • [ 1206675-01-5 ]
  • C15H11(2)H3BNO2 [ No CAS ]
  • 19
  • [ 1206675-01-5 ]
  • [ 308103-40-4 ]
  • C15H14BNO2 [ No CAS ]
  • 20
  • [ 932-30-9 ]
  • [ 64-19-7 ]
  • [ 1206675-01-5 ]
YieldReaction ConditionsOperation in experiment
35.4 g 9. The dried solid was dissolved in 420 g of glacial acetic acid and stirred for 16-24 hours.10. To the reaction system, 932 g of methyl tert-butyl ether was added, and the mixture was stirred and crystallized at 0 to 10 C for 4 to 6 hours.11. Centrifuge the system, centrifuge the solids with 250 ml of 85% ethanol and centrifuge again.12. Centrifuge the solid at 40-50 C to dry, to obtain the final product 35.4g, white.
  • 21
  • [ 90-02-8 ]
  • [ 1206675-01-5 ]
  • 22
  • [ 64-19-7 ]
  • [ 390427-07-3 ]
  • [ 1206675-01-5 ]
YieldReaction ConditionsOperation in experiment
67.07% Reflux; The compound of formula 2 (10.0g),Glacial acetic acid (50.0mL) was added to the reaction flask and stirred,Stop the reaction after refluxing for 6h7h,Cool down to below 20,Slowly add MTBE (150mL) to crystallize,Stir at 1020 for 0.5h, filter,Dry under vacuum at 40 to constant weight;Weight: 5.50g; Yield: 67.07%;Purity: 98.64%.
42 g Methanol (350 ml) and the crude product (1.00 eq) obtained in Example 1 were added to a 1 L reaction flask at 15-30 C, and water (50 ml L) and concentrated hydrochloric acid (100 ml, 2.00 eq) were added to a 1 L reaction flask.After stirring at 15-30 C for 16 hours, the sample was detected by HPLC to <0.5% of the starting material.After the reaction, the system is concentrated to remove methanol, and 500 ml of water is added to the concentrated system to form a solution.The phase is then extracted with ethyl acetate (350 ml * 2), the aqueous phase is extracted after the extraction, the pH is adjusted to 7-8 by adding 85 g of sodium hydrogencarbonate, and the mixture is extracted with 2-methyltetrahydrofuran 4 times, 700 ml each time;The organic phase is concentrated to dryness to give a yellow solid;Soluble in 350ml acetic acid,Stir at 16-30 C for 16 hrs.Add 1000 ml of methyl tert-butyl ether to the system.Solid precipitated, stirred at 15-30 C for 1-2hrs; suction filtration,The filter cake was rinsed with methyl tert-butyl ether; the product was dried to give 42 g.
 

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