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Chemical Structure| 1211583-11-7 Chemical Structure| 1211583-11-7

Structure of 1211583-11-7

Chemical Structure| 1211583-11-7

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Product Details of [ 1211583-11-7 ]

CAS No. :1211583-11-7
Formula : C5H3BrClNO
M.W : 208.44
SMILES Code : OC1=C(Cl)C=CN=C1Br
MDL No. :MFCD18257594

Safety of [ 1211583-11-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1211583-11-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1211583-11-7 ]

[ 1211583-11-7 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 1211583-11-7 ]
  • [ 74-88-4 ]
  • [ 1256819-68-7 ]
YieldReaction ConditionsOperation in experiment
78% With potassium carbonate; In acetone; at 20.0℃; for 18.0h;Inert atmosphere; <strong>[1211583-11-7]2-bromo-4-chloropyridin-3-ol</strong> (8.15 g, 39.1 mmol), potassium carbonate (10.5 g, 76 mmol) and iodomethane (3.65 ml, 58.6 mmol) were added to acetone (300 ml) and stirred for 18h at room temperature under inert conditions. The reaction mixture was evaporated to dryness, dissolved in ethyl acetate (100 mL), filtered over silica gel and the filter washed with ethyl acetate (3 x 100 mL). The filtrate was evaporated to dryness to obtain crude product which was purified over silica gel using 0:1 to 1 :0 ethyl acetate in heptane to obtain 2-bromo-4-chloro-3- methoxypyridine as a white crystalline solid (6.8 g, 78%). ESI-MS m/z: 224 (M+H)+; 1 H NMR (400 MHz, CDCI3) delta ppm 8.06 (d, J = 3.6Hz, 1 H), 7.31 (d, J = 5.0Hz, 1 H), 3.95 (s, 1 H).
  • 2
  • [ 1211583-11-7 ]
  • (4-chloro-3-methoxy-pyridin-2-yl)cyclopropylmethane-1-ol [ No CAS ]
  • 3
  • [ 1211583-11-7 ]
  • (4-chloro-3-methoxy-2-pyridyl)cyclopropyl-methanone [ No CAS ]
  • 4
  • [ 1211583-11-7 ]
  • 2-(4-chloro-3-methoxypyridin-2-yl)-2-cyclopropyl-acetaldehyde [ No CAS ]
  • 5
  • [ 1211583-11-7 ]
  • [ 335428-56-3 ]
  • 6
  • [ 1211583-11-7 ]
  • [ 1392845-44-1 ]
  • 7
  • [ 1211583-11-7 ]
  • C16H18ClNO5 [ No CAS ]
 

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