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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 1219813-78-1 Chemical Structure| 1219813-78-1

Structure of 1219813-78-1

Chemical Structure| 1219813-78-1

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Product Details of [ 1219813-78-1 ]

CAS No. :1219813-78-1
Formula : C12H20BrNO3
M.W : 306.20
SMILES Code : O=C(N1CC(C(CBr)=O)CCC1)OC(C)(C)C
MDL No. :MFCD18250319
InChI Key :FTDGLGFKVKVHTE-UHFFFAOYSA-N
Pubchem ID :58360219

Safety of [ 1219813-78-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H332-H335-H314
Precautionary Statements:P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 1219813-78-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1219813-78-1 ]

[ 1219813-78-1 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 1219813-78-1 ]
  • [ 49548-40-5 ]
  • tert-butyl 3-[2-(benzyloxycarbonylaminomethyl)thiazol-4-yl]piperidine-1-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
79% With potassium carbonate; In ethanol; at 20.0℃; K2CO3 (228 mg, 1.65 mmol) was added to a solution of <strong>[1219813-78-1]tert-butyl 3-(2-bromoacetyl)piperidine-1-carboxylate</strong> (500 mg, 1.63 mmol) and N-benzyloxycarbonylglycine thioamide (366 mg, 1.63 mmol) in EtOH (8 mL) at room temperature. The reaction mixture was stirred at room temperature overnight and evaporated. The residue was dissolved in DCM (10 mL), washed with water (10 mL) and saline (10 mL), dried and evaporated. The crude product was purified by chromatography on silica eluting with 0-100% EtOAc in hexane affording a yellow gum (558 mg, 79%). M/z 454 (M+Na)+.
  • 3
  • [ 1219813-78-1 ]
  • [ 49548-40-5 ]
  • C2HF3O2*C17H21N3O2S [ No CAS ]
 

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Technical Information

• Acyl Group Substitution • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Chan-Lam Coupling Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Dihalides • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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