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Chemical Structure| 1220229-87-7 Chemical Structure| 1220229-87-7

Structure of 1220229-87-7

Chemical Structure| 1220229-87-7

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Product Details of [ 1220229-87-7 ]

CAS No. :1220229-87-7
Formula : C9H5BrClNO3S
M.W : 322.56
SMILES Code : O=S(C1=CN=C(O)C2=C1C=C(Br)C=C2)(Cl)=O
MDL No. :MFCD27756715

Safety of [ 1220229-87-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H335-H314
Precautionary Statements:P260-P264-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 1220229-87-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1220229-87-7 ]

[ 1220229-87-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 169448-87-7 ]
  • [ 1220229-87-7 ]
  • [ 1220230-01-2 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In tetrahydrofuran; at 20℃; To a solution of tert-butyl (2f?)-2-(hydroxymethyl)piperazine-1-carboxy.ate (0.479 g) and triethylamine (0.618 ml_) in THF (6 ml_) was added dropwise a solution of 6-bromo-1-oxo- 1 ,2-dihydroisoquinoline-4-sulfonyl chloride (Example 46a, 0.715 g) in THF (10 ml_). The reaction was stirred at room temperature for 20 min. The resulting solution was concentrated under reduced pressure before adding water and extracting into ethyl acetate. The combined organics were dried (MgSO4), filtered and evaporated under reduced pressure. Trituration with ethyl acetate gave the subtitle compound (0.855 g). MS: APCI(-ve) 500 / 504 (M-H)" 1H NMR delta (CDCI3) 8.34 (d, 1 H), 8.30 (d, 1 H), 8.05 (s, 1 H), 7.73 (dd, 1 H), 4.32 - 4.18 (m, 1H), 4.00 (d, 1 H), 3.88 (d, 1 H), 3.72 (d, 1 H), 3.63 (d, 2H), 3.10 - 2.96 (m, 1 H), 2.84 (td, 2H), 1.44 (s, 9H)
 

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