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Chemical Structure| 122775-34-2 Chemical Structure| 122775-34-2

Structure of 122775-34-2

Chemical Structure| 122775-34-2

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Product Details of [ 122775-34-2 ]

CAS No. :122775-34-2
Formula : C9H5IO2
M.W : 272.04
SMILES Code : O=C1C(I)=COC2=C1C=CC=C2
MDL No. :MFCD09475514

Safety of [ 122775-34-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 122775-34-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 122775-34-2 ]

[ 122775-34-2 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 122775-34-2 ]
  • [ 98-80-6 ]
  • [ 574-12-9 ]
YieldReaction ConditionsOperation in experiment
90% With palladium 10% on activated carbon; sodium carbonate; In 1,2-dimethoxyethane; water; at 45℃; for 4h; General procedure: The iodochromones (1 equiv.) were suspended in dimethoxyethane/water (1:1) and stirred at room temperature. Sodium carbonate (3.0 equiv.) was added followed by the appropriate boronic acid (1.2 equiv.). 10 % Pd/C (5 mol %) was added and the reaction mixture stirred at 45C for 4h. The reaction mixture was filtered through a short pad of celite. The catalyst was washed using water and dichloromethane and the filtrate partitioned into dichloromethane. The organic fraction was dried using anhydrous sodium sulphate and the solvent evaporated in vacuo. The crude product was subjected to flash chromatography eluted using n-hexanes and ethyl acetate. -phenyl-4H-chrome-4-one (15) White solid (43mg, 90%) m.p. 129C, Rf (EtOAc: Hexane 2:8) 0.37, 1H NMR (400 MHz, CDCl3) delta 8.33 (d, J = 8.0 Hz, 1H, H-5), 8.03 (s, 1H, H-2), 7.69 (m, 1H, Ar-H), 7.58 (m, 2H, Ar-H), 7.44 (m, 5H, Ar-H). 13C NMR (101 MHz, CDCl3) delta 176.2, 156.3, 153.0, 133.6, 131.9, 129.0, 129.0, 128.5, 128.2, 126.5, 125.5, 125.3, 124.7, 118.0 m/z (LRMS, EI) Found 222 (M+) C15H10O2 requires M, 222.07. HPLC 99 % (Method B, tR 10.64min)
  • 2
  • [ 122775-34-2 ]
  • [ 175883-62-2 ]
  • C17H14O3 [ No CAS ]
  • 3
  • [ 603-33-8 ]
  • [ 122775-34-2 ]
  • [ 574-12-9 ]
  • 4
  • [ 122775-34-2 ]
  • [ 229009-41-0 ]
  • [ 1289141-71-4 ]
  • 5
  • [ 122775-34-2 ]
  • [ 229009-41-0 ]
  • [ 1289141-95-2 ]
  • 6
  • [ 456-14-4 ]
  • [ 122775-34-2 ]
  • [ 1449754-21-5 ]
  • 7
  • [ 57508-48-2 ]
  • [ 122775-34-2 ]
  • ethyl 2-amino-5-(2-hydroxybenzoyl)-1H-pyrrole-3-carboxylate [ No CAS ]
  • 8
  • [ 38111-44-3 ]
  • [ 122775-34-2 ]
  • [ 574-12-9 ]
 

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