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Chemical Structure| 1228392-59-3 Chemical Structure| 1228392-59-3

Structure of 1228392-59-3

Chemical Structure| 1228392-59-3

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Product Details of [ 1228392-59-3 ]

CAS No. :1228392-59-3
Formula : C16H21BrN2O6
M.W : 417.25
SMILES Code : BrC1=CC([N+]([O-])=O)=C(N(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C=C1
MDL No. :MFCD31560548
InChI Key :CPVNSGCXUGJJOL-UHFFFAOYSA-N
Pubchem ID :118029324

Safety of [ 1228392-59-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1228392-59-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1228392-59-3 ]

[ 1228392-59-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1228392-59-3 ]
  • [ 145214-05-7 ]
  • C19H23N3O7 [ No CAS ]
YieldReaction ConditionsOperation in experiment
51.4% With tetrakis(triphenylphosphine) palladium(0); In toluene; at 80℃; for 3h;Inert atmosphere; Under the protection of nitrogen at room temperature, compound 4A (1.00 g, 2.40 mmol) was dissolved in toluene (10.0 mL).Subsequently, <strong>[145214-05-7]2-(tributylstannyl)oxazole</strong> (940 mg, 2.61 mmol) and tetrakis(triphenylphosphine)palladium (280 mg, 0.24 mmol) were added to the above solution.The reaction solution was heated to 80 degrees Celsius and stirred for 3 hours.After LCMS monitoring showed that the starting material disappeared, the mixed solution was concentrated under reduced pressure.The obtained residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 3/1) to obtain 500 mg of orange solid compound 46A (yield: 51.4%).
 

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