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Chemical Structure| 1252793-57-9 Chemical Structure| 1252793-57-9

Structure of 1252793-57-9

Chemical Structure| 1252793-57-9

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Product Details of [ 1252793-57-9 ]

CAS No. :1252793-57-9
Formula : C15H21BO2
M.W : 244.14
SMILES Code : CC1(C)C(C)(C)OB(C2=CC=CC3=C2CCC3)O1
MDL No. :MFCD18383480
InChI Key :DYTLGZWBDATBAZ-UHFFFAOYSA-N
Pubchem ID :68344390

Safety of [ 1252793-57-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1252793-57-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1252793-57-9 ]

[ 1252793-57-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6134-53-8 ]
  • [ 73183-34-3 ]
  • [ 1252793-57-9 ]
YieldReaction ConditionsOperation in experiment
57% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 90℃; for 4h;Inert atmosphere; A mixture of <strong>[6134-53-8]<strong>[6134-53-8]4-bromoindan</strong>e</strong> (60.0 mg, 304 umol), bis(pinacolato)diboron (92.7 mg, 365 umol), potassium acetate (59.7 mg, 608 umol) and Pd(dppf)Cl2 (11.1 mg, 15.2 umol) in dioxane (10 mL) was stirred at 90 C for 4 hrs under nitrogen. On completion, the reaction mixture was concentrated in vacuo. The residue was purified by silica gel chromatography (petroleum ether:ethyl acetate = 50:1) to give the title compound (50.0 mg, 57% yield) as a colorless oil.1H NMR (400MHz, CDCl3) delta = 7.60 (d, J = 7.2 Hz, 1H), 7.32 (d, J = 7.2 Hz, 1H), 7.14 (dd, J = 7.2, 7.2 Hz, 1H), 3.14 (t, J = 7.6 Hz, 2H), 2.90 (t, J = 7.6 Hz, 2H), 2.05 (m, 2H), 1.34 (s, 12H). (Intermediate C) 2-(1,3-Dihydroisobenzofuran-4-yl)-4,4,5,5-tetramethyl-1,3,2- dioxaborolane
 

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