Home Cart 0 Sign in  
X

[ CAS No. 1256806-53-7 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
3d Animation Molecule Structure of 1256806-53-7
Chemical Structure| 1256806-53-7
Chemical Structure| 1256806-53-7
Structure of 1256806-53-7 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 1256806-53-7 ]

Related Doc. of [ 1256806-53-7 ]

Alternatived Products of [ 1256806-53-7 ]

Product Details of [ 1256806-53-7 ]

CAS No. :1256806-53-7 MDL No. :MFCD18256598
Formula : C6H4FNO3 Boiling Point : -
Linear Structure Formula :- InChI Key :ZIUMHELXLSUNJQ-UHFFFAOYSA-N
M.W : 157.10 Pubchem ID :58449071
Synonyms :

Safety of [ 1256806-53-7 ]

Signal Word:Danger Class:6.1
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501 UN#:2811
Hazard Statements:H301-H311-H331 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1256806-53-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1256806-53-7 ]

[ 1256806-53-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 745784-04-7 ]
  • 3-fluoro-5-hydroxypicolinic acid [ No CAS ]
  • 5-fluoro-3-hydroxypicolinic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With lithium hydroxide monohydrate; In water; at 100℃; for 20h;Sealed tube; To a sealable tube was added <strong>[745784-04-7]3,5-difluoropyridine-2-carboxylic acid</strong> (2.0 g, 12.57 mmol, Lancaster Synthesis Ltd.), lithium hydroxide hydrate (5.28 g, 126 mmol, Aldrich), and water (50 mL). The resulting mixture was stirred at 100 C for 20 h. Then the mixture was cooled to RT and TFA (5.0 mL, 67.3 mmol, Aldrich) was added to the A-1813-WO-PCT - 185 - mixture. The mixture was concentrated and dried in vacuo overnight to provide 12.6 g of a crude product mixture of 3-fluoro-5-hydroxypicolinic acid and 5-fluoro-3- hydroxypicolinic acid, as a white solid, used directly in the next step. MS (ESI, positive ion) m/z: 158.1 (M+H) observed for both isomers
  • 2
  • [ 745784-04-7 ]
  • 3-fluoro-5-hydroxypicolinic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With lithium hydroxide; In tetrahydrofuran; water; at 100℃; for 18h; Step 1: (0542) To <strong>[745784-04-7]3,5-difluoropyridine-2-carboxylic acid</strong> (3.0 g, 19 mmol) in THF (30 mL) in a glass tube reaction vessel was added 2N LiOH(aq). The reaction mixture was capped and warmed to 100 C. The reaction was stirred for 18 h and then cooled to room temperature. TFA (5 mL) was added and the reaction was concentrated in vacuo. The residue was purified by reverse phase chromatography [C18 (360 g) 0.1% formic acid/water for 20 minutes followed by 0-100% 0.1% formic acid/acetonitrile//0.1% formic acid/water] to provide the hydroxy pyridine (2.1 g) as a 1:1 mixture of starting material and product. The mixture was carried on directly.
Same Skeleton Products
Historical Records

Related Functional Groups of
[ 1256806-53-7 ]

Fluorinated Building Blocks

Chemical Structure| 1227511-52-5

[ 1227511-52-5 ]

3-Fluoro-5-methoxypicolinic acid

Similarity: 0.94

Chemical Structure| 1256836-96-0

[ 1256836-96-0 ]

Methyl 3-fluoro-5-hydroxypicolinate

Similarity: 0.91

Chemical Structure| 1256787-03-7

[ 1256787-03-7 ]

Methyl 3-fluoro-5-methoxypicolinate

Similarity: 0.88

Chemical Structure| 1286777-33-0

[ 1286777-33-0 ]

5-(Difluoromethoxy)-3-fluoropicolinic acid

Similarity: 0.88

Chemical Structure| 152126-31-3

[ 152126-31-3 ]

3-Fluoropicolinic acid

Similarity: 0.87

Alcohols

Chemical Structure| 1256836-96-0

[ 1256836-96-0 ]

Methyl 3-fluoro-5-hydroxypicolinate

Similarity: 0.91

Carboxylic Acids

Chemical Structure| 1227511-52-5

[ 1227511-52-5 ]

3-Fluoro-5-methoxypicolinic acid

Similarity: 0.94

Chemical Structure| 1286777-33-0

[ 1286777-33-0 ]

5-(Difluoromethoxy)-3-fluoropicolinic acid

Similarity: 0.88

Chemical Structure| 152126-31-3

[ 152126-31-3 ]

3-Fluoropicolinic acid

Similarity: 0.87

Chemical Structure| 1260890-41-2

[ 1260890-41-2 ]

3-Fluoropyridine-2-carboxylic Acid Hydrochloride

Similarity: 0.86

Chemical Structure| 1256806-43-5

[ 1256806-43-5 ]

3-Fluoro-6-methylpicolinic acid

Similarity: 0.86

Related Parent Nucleus of
[ 1256806-53-7 ]

Pyridines

Chemical Structure| 1227511-52-5

[ 1227511-52-5 ]

3-Fluoro-5-methoxypicolinic acid

Similarity: 0.94

Chemical Structure| 1256836-96-0

[ 1256836-96-0 ]

Methyl 3-fluoro-5-hydroxypicolinate

Similarity: 0.91

Chemical Structure| 1256787-03-7

[ 1256787-03-7 ]

Methyl 3-fluoro-5-methoxypicolinate

Similarity: 0.88

Chemical Structure| 1286777-33-0

[ 1286777-33-0 ]

5-(Difluoromethoxy)-3-fluoropicolinic acid

Similarity: 0.88

Chemical Structure| 152126-31-3

[ 152126-31-3 ]

3-Fluoropicolinic acid

Similarity: 0.87