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Chemical Structure| 1282516-62-4 Chemical Structure| 1282516-62-4

Structure of 1282516-62-4

Chemical Structure| 1282516-62-4

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Product Details of [ 1282516-62-4 ]

CAS No. :1282516-62-4
Formula : C13H11IN2O3
M.W : 370.14
SMILES Code : O=C(C1=CC=C2C3=NC(I)=CN3CCOC2=C1)OC
MDL No. :MFCD22581523

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Application In Synthesis of [ 1282516-62-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1282516-62-4 ]

[ 1282516-62-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1282516-62-4 ]
  • [ 216019-28-2 ]
  • [ 1282513-42-1 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate;tetrakis(triphenylphosphine) palladium(0); In water; acetonitrile; at 140℃; for 0.166667h;Microwave irradiation; Example 296 methyl 2-(3-isopropylphenyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-9-carboxylate 296 Methyl 2-iodo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-9-carboxylate (80 mg, 1 eq), <strong>[216019-28-2]3-isopropylphenylboronic acid</strong> (65 mg, 1.75 eq), and tetrakis(triphenylphosphine)palladium (10 mg, 0.05 eq), in 1.0 M aqueous sodium carbonate (1.0 mL) and acetonitrile (1.0 mL) were heated to 140 C. for 10 min in a sealed microwave reactor. The crude reaction mixture was concentrated and purified using reverse phase HPLC to yield 296 (4 mg). ESI-MS: 363.1 (M)+
 

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